Protein Alignment Lkr and si:dkey-202l22.3

DIOPT Version :10

• Sequence 1: NP_647968.3
• Gene: Lkr / 38622
• FlyBaseID: FBgn0035610
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: NP_001108620.1
• Gene: si:dkey-202l22.3 / 100002553
• ZFINID: ZDB-GENE-131127-471
• Length: 377
• Species: Danio rerio
• Alignment Length: 308
• Identity: 90/308 - (29%)
• Similarity: 151/308 - (49%)
• Gaps: 31/308 - (10%)

  Fly    42 YGGISIVAVIGNTLVIWVVATTRQMRTVTNMYIANLAFADVIIGLFCIP----FQFQAALLQSWN 102
            |..:.:||.:||:.::..:...:::...||.:|.|||..|:::.|.|:|    :.|.|   |.|.
Zfish    45 YALVVVVAGVGNSFLLACILADKKLHNATNFFIGNLAAGDLLMCLSCVPLTASYAFDA---QGWA 106

  Fly   103 LPWFMCSFCPFVQALSVNVSVFTLTAIAIDRHRAIINPLRARPTKFVSKFIIGGIWMLALLFAVP 167
            ....||...|.||..:|..||.:|||||:||:..:..|:|.|.:.:....:..|:|.::|..|.|
Zfish   107 FGRPMCHLIPLVQGATVFASVLSLTAIAMDRYVVVAYPVRRRISVWGCGAVALGVWAVSLALAAP 171

  Fly   168 FAIAFRVEELTERFRENNETYNVTRPFCMNKNLSDD-----QLQSFRYTLVFV--QYLVPFCVIS 225
            .::..|..:|              ||..|...:.::     :.|...|:..|:  .|::|...:|
Zfish   172 PSLHTRYVDL--------------RPSGMELVVCEEFWLGAERQRLLYSCFFLLASYMIPLLSVS 222

  Fly   226 FVYIQMAVRLWGTRAPGNAQDSRDITLLKNKKKVIKMLIIVVIIFGLCWLPLQLYNILYVTIP-- 288
            ..|..::|.|.....||....|:. ...|.::|...:|:..|:.|.|||||||:.|:|.....
Zfish   223 ISYCAISVHLRKHTLPGEPSQSQQ-RWSKQRRKTFSLLVASVLAFALCWLPLQVLNLLLDLDSDF 286

  Fly   289 EINDYHFISIVWFCCDWLAMSNSCYNPFIYGIYNEKFKREFNKRFAAC 336
            :|.|.|:::::...|..:|||::|||||||...:.|.:......|..|
Zfish   287 QIVDKHYVNVLQVSCHLIAMSSACYNPFIYASLHSKVRMHLRGYFCPC 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lkr	NP_647968.3	7tmA_leucokinin-like	36..329	CDD:320515	88/299 (29%)
		TM helix 1	37..63	CDD:320515	5/20 (25%)
		TM helix 2	70..95	CDD:320515	11/28 (39%)
		TM helix 3	108..138	CDD:320515	14/29 (48%)
		TM helix 4	149..170	CDD:320515	5/20 (25%)
		TM helix 5	205..234	CDD:320515	7/30 (23%)
		TM helix 6	254..284	CDD:320515	13/29 (45%)
		TM helix 7	297..322	CDD:320515	11/24 (46%)
si:dkey-202l22.3	NP_001108620.1	7tm_GPCRs	39..327	CDD:475119	88/299 (29%)
		TM helix 1	41..65	CDD:410628	5/19 (26%)
		TM helix 2	74..96	CDD:410628	9/21 (43%)
		TM helix 3	113..135	CDD:410628	10/21 (48%)
		TM helix 4	156..172	CDD:410628	4/15 (27%)
		TM helix 5	203..226	CDD:410628	5/22 (23%)
		TM helix 6	256..278	CDD:410628	10/21 (48%)
		TM helix 7	295..320	CDD:410628	11/24 (46%)