DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment blanks and Adarb2

DIOPT Version :9

Sequence 1:	NP_647966.1	Gene:	blanks / 38620	FlyBaseID:	FBgn0035608	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	XP_017171136.1	Gene:	Adarb2 / 94191	MGIID:	2151118	Length:	747	Species:	Mus musculus

Alignment Length:	338	Identity:	79/338 - (23%)
Similarity:	125/338 - (36%)	Gaps:	59/338 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 SAEEDAVAVIP--LADNLKKTAMGGENKSDEKGTVSSEPKALSDQITSSMRVTKNK-IADDKSSD 89
            |..:|.|:::.  ||. .|..:.|..|..||..        ||   |||..|.:|: :::..:..
Mouse    30 SKRKDKVSILSTFLAP-FKYLSPGTTNTEDEDN--------LS---TSSAEVKENRNVSNLGTRP 82

  Fly    90 VITDDATNGRKKQKKNKK----------AKI----RPLTMPVTSKDALMVLNELKGVTVDNM--Q 138
            :...|...|.....|.|:          .|:    :.|:..||.|:||:.|:|||......|  |
Mouse    83 LPPGDWARGSTPSVKRKRPLEEGNGGHFCKLQLIWKKLSWSVTPKNALVQLHELKPGLQYRMVSQ 147

  Fly   139 IKRDHEGKIMARVVVNSKKYEAEGSSVNSARNAACEKALQEIL--TTKMKAVL-----DGPGKSL 196
            ....|.......|.||...:|..|.:...|:..|.|.||:..:  ....:|.|     ..|....
Mouse   148 TGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAEMALKSFVQFPNAFQAHLAMGSSTSPCTDF 212

  Fly   197 ESDEDDILEKMASYAIHKLGEEWKTDD------IDV----------ATLYNDLKNKQTSVVEPKK 245
            .||:.|..:.:    ..:.....|.:|      :|.          ..||:.|.....::.:..:
Mouse   213 TSDQADFPDTL----FKEFEPSSKNEDFPGCHPVDTEFLSSAYRRGRLLYHTLDLMGQALPDRSR 273

  Fly   246 PLPETWKNMHPCMVLNYMRPQCTFIVSGGTGTNQN-NTFSMSVCVDNCEFNAEGPSKKAARYKLS 309
            ..|......:|.:|||.:|....::....|..... .:|.|:||||...|...|.|||.|:.:.:
Mouse   274 LAPGALGERNPVVVLNELRSGLRYVCLSETAEKPRVKSFVMAVCVDGRTFEGSGRSKKLAKGQAA 338

  Fly   310 ALVCNKLFGTDYP 322
            ......||....|
Mouse   339 QAALQALFDIRLP 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
blanks	NP_647966.1	None
Adarb2	XP_017171136.1	DSRM_RED2_rpt1	122..195	CDD:380725	22/72 (31%)
		DSRM_SF	276..349	CDD:381777	21/72 (29%)
		ADEAMc	366..739	CDD:214718
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167848534
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10910
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030