DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment blanks and STAU1

DIOPT Version :9

Sequence 1:	NP_647966.1	Gene:	blanks / 38620	FlyBaseID:	FBgn0035608	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_001309861.1	Gene:	STAU1 / 6780	HGNCID:	11370	Length:	583	Species:	Homo sapiens

Alignment Length:	289	Identity:	60/289 - (20%)
Similarity:	112/289 - (38%)	Gaps:	68/289 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 AMGGENKSDEKGTVSSEPKALSDQITSSMRVTKNKIADDKSSDVITDDATNGRKKQKKNKKAKIR 111
            ::||:..:   |...:...|..|....::|:.:|:...::..       .|||:.:::|
Human   132 SVGGQQFN---GKGKTRQAAKHDAAAKALRILQNEPLPERLE-------VNGRESEEEN------ 180

  Fly   112 PLTMPVTSKDALMVLNELKGVTVDNMQIKRDHEGKIMARVVVNSK----KYEAEGSSVNSARNAA 172
                          ||:.:...|..:.:||:        :.||.:    |..|..|.....:|..
Human   181 --------------LNKSEISQVFEIALKRN--------LPVNFESFPLKQVARESGPPHMKNFV 223

  Fly   173 CEKALQEILTTKMKAVLDGPGKSLESDEDDILEKMASYAIHKLGEEWKTDDID-VATLYNDLKNK 236
            .:.::.|.       |.:|.|||.:     |.:|.|:.|:  |.|..|...:. |..:...:|.|
Human   224 TKVSVGEF-------VGEGEGKSKK-----ISKKNAAIAV--LEELKKLPPLPAVERVKPRIKKK 274

  Fly   237 QTSVVEPKKPLPETWKNMHPCMVLNYMR-------PQCTFIVSGGTGTNQNNTFSMSVCVDNCEF 294
            ...:|:|:.. ||..:.::|...|..::       |:.|.:..  .|..:...|.|.|.|.|...
Human   275 TKPIVKPQTS-PEYGQGINPISRLAQIQQAKKEKEPEYTLLTE--RGLPRRREFVMQVKVGNHTA 336

  Fly   295 NAEGPSKKAARYKLSALVCNKLFGTDYPQ 323
            ...|.:||.|: :.:|....::.|...||
Human   337 EGTGTNKKVAK-RNAAENMLEILGFKVPQ 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
blanks	NP_647966.1	None
STAU1	NP_001309861.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	34..55
		DSRM	186..256	CDD:214634	21/91 (23%)
		DSRM	292..358	CDD:238007	15/68 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	366..403
		Staufen_C	454..563	CDD:293091
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158112
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930