DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment blanks and adarb2

DIOPT Version :9

Sequence 1:	NP_647966.1	Gene:	blanks / 38620	FlyBaseID:	FBgn0035608	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	XP_686426.5	Gene:	adarb2 / 558149	ZFINID:	ZDB-GENE-060503-160	Length:	740	Species:	Danio rerio

Alignment Length:	308	Identity:	71/308 - (23%)
Similarity:	120/308 - (38%)	Gaps:	66/308 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 NKSDEKGTVSSEPKALSDQITSSMRVTKNK----------IADDKSSDVITD---DATNGRKKQK 103
            |.::::.|:|          |||..|.:|:          :..|..:...:|   |..:|.|:::
Zfish    45 NGTEDEDTLS----------TSSAEVKENRNTGNLEDCAIVTSDCQTLFFSDSPRDGASGLKRKR 99

  Fly   104 ---KNKKAKIRPLTM-------PVTSKDALMVLNELKGVTVDNM--QIKRDHEGKIMARVVVNSK 156
               ::....:|.|.:       ....|:||:.||||:......|  |....|.......|.||..
Zfish   100 PLEEDNNGHLRKLRLYCKKLAWSDAPKNALVQLNELRPGLQYRMVSQTGPVHAPLFSIAVEVNGL 164

  Fly   157 KYEAEGSSVNSARNAACEKALQEIL----TTKMKAVLDG---PGKSLESDEDDILEKMASYAIHK 214
            .:|..|.:...|:..|.|.||:..:    .::....:.|   |.....||:.|..:        .
Zfish   165 TFEGTGPTKKKAKMKAAEMALKSFIQFPNASQAHLAMGGLSNPTADFTSDQADFPD--------T 221

  Fly   215 LGEEWKTDDIDVA---TLYNDLKNKQT---SVVEPKK------PLPETWKNMHPCMVLNYMRPQC 267
            |.:.::.|....|   .|.:.|:.:.|   .||:.::      |.|.:.....|.::||.:||..
Zfish   222 LFKGFEPDGCRSAENELLSSALRLRHTLDLMVVQARQEDPCLPPAPVSPPQPSPVVLLNDLRPGL 286

  Fly   268 TF--IVSGGTGTNQNNTFSMSVCVDNCEFNAEGPSKKAARYKLSALVC 313
            .:  :.....|...:.:|.|:|.||...|...|.|||.|  |..|.||
Zfish   287 RYACLSEHAQGKRAHRSFIMAVRVDGRIFEGSGRSKKQA--KRQAAVC 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
blanks	NP_647966.1	None
adarb2	XP_686426.5	DSRM	125..>172	CDD:214634	15/46 (33%)
		dsrm	278..337	CDD:278464	20/57 (35%)
		ADEAMc	364..737	CDD:214718
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594032
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10910
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.030