DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment blanks and STAU2

DIOPT Version :9

Sequence 1:	NP_647966.1	Gene:	blanks / 38620	FlyBaseID:	FBgn0035608	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_001157852.1	Gene:	STAU2 / 27067	HGNCID:	11371	Length:	570	Species:	Homo sapiens

Alignment Length:	218	Identity:	47/218 - (21%)
Similarity:	79/218 - (36%)	Gaps:	50/218 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 KDALMVLNELKGVTVDNMQIK------RDHEGKIMARVVVNSKKYEAEGSSVNSARNAACEKALQ 178
            |.|:.::|||........|.|      ..|......::.:..:.:|:||||:..|:.|...|||.
Human     7 KTAMCLVNELARFNRVQPQYKLLNERGPAHSKMFSVQLSLGEQTWESEGSSIKKAQQAVANKALT 71

  Fly   179 EILTTKMKAVLDGPGKSLESDEDDILEKMASYAIHKLGEEWKTDDIDVATLYNDLKNKQTSVVEP 243
            |  :|..|.|...|..::.::...|                 |..:::..|  .:|..:.::..|
Human    72 E--STLPKPVQKPPKSNVNNNPGSI-----------------TPTVELNGL--AMKRGEPAIYRP 115

  Fly   244 KKPLPETWKNMHPCMVLNY-------MRPQCTFIVSGGTGTNQNNTFSMSVCVDNCEFNAEGPSK 301
            ..|.|      .|....||       .|..|..          ...|.:.:.|.|.||..||.::
Human   116 LDPKP------FPNYRANYNFRGMYNQRYHCPV----------PKIFYVQLTVGNNEFFGEGKTR 164

  Fly   302 KAARYKLSALVCNKLFGTDYPQK 324
            :|||:..:......|.....|::
Human   165 QAARHNAAMKALQALQNEPIPER 187

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
blanks	NP_647966.1	None
STAU2	NP_001157852.1	DSRM	9..70	CDD:214634	15/60 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	71..94		5/24 (21%)
		DSRM	96..180	CDD:214634	20/101 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	181..203		1/7 (14%)
		DSRM	209..273	CDD:214634
		Nuclear localization signal 1. /evidence=ECO:0000250	273..291
		DSRM	308..374	CDD:214634
		Nuclear localization signal 2. /evidence=ECO:0000250	373..412
		Required for dendritic transport. /evidence=ECO:0000250	381..570
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	387..409
		Staufen_C	459..523	CDD:318642
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	528..570
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158151
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930