DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment blanks and ZFR2

DIOPT Version :9

Sequence 1:	NP_647966.1	Gene:	blanks / 38620	FlyBaseID:	FBgn0035608	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	XP_011526133.1	Gene:	ZFR2 / 23217	HGNCID:	29189	Length:	940	Species:	Homo sapiens

Alignment Length:	286	Identity:	51/286 - (17%)
Similarity:	97/286 - (33%)	Gaps:	109/286 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 SDVITDDATNGRKKQKKNKKAKIRPLT--------MPVTSKDALM-------------------- 124
            ||.:.:: ..||::::.:|::.:.|.|        :.:.:|..|:
Human   625 SDTLAEE-DRGRREEEGDKRSSVAPQTRVLKGVMRVGILAKGLLLRGDRNVRLALLCSEKPTHSL 688

  Fly   125 -------VLNELKGVTVDNMQIKRDHEGKIMARVVVNSKKYEAEGSSVNSARNAACEK-ALQEIL 181
                   :..:|:.||.|..::..|.|    |.:|::|                 ||: .:|..:
Human   689 LRRIAQQLPRQLQMVTEDEYEVSSDPE----ANIVISS-----------------CEEPRMQVTI 732

  Fly   182 TTKMKAVLDGPGKSLESDEDDILEKMASYAIHKLGEEWKTDDIDVATLYNDLKNKQTSVVEPKKP 246
            :.....:.:.|    .:|.:.:             ||.:.|..|              |:.|||.
Human   733 SVTSPLMREDP----STDPEGV-------------EEPQADAGD--------------VLSPKKC 766

  Fly   247 LPE-------TW-----KNMHPC-MVLNYMRPQCTFIVSGGTGTNQNNTFSMSVCVDNCEFNAEG 298
            |..       .|     ..:.|| :|:..:|..|..:.:.|.    ...::|.:.|:....:|.|
Human   767 LESLAALRHARWFQARASGLQPCVIVIRVLRDLCRRVPTWGA----LPAWAMELLVEKAVSSAAG 827

  Fly   299 P--SKKAARYKLSALVCNKLFGTDYP 322
            |  ...|.|..|..:....|. ||.|
Human   828 PLGPGDAVRRVLECVATGTLL-TDGP 852

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
blanks	NP_647966.1	None
ZFR2	XP_011526133.1	ZnF_U1	271..300	CDD:197732
		C2H2 Zn finger	273..295	CDD:275371
		ZnF_U1	318..350	CDD:197732
		C2H2 Zn finger	321..343	CDD:275371
		ZnF_U1	467..498	CDD:197732
		C2H2 Zn finger	470..492	CDD:275371
		DZF	652..905	CDD:128842	44/258 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158134
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930