DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment blanks and Adarb1

DIOPT Version :9

Sequence 1:	NP_647966.1	Gene:	blanks / 38620	FlyBaseID:	FBgn0035608	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	XP_006513125.1	Gene:	Adarb1 / 110532	MGIID:	891999	Length:	775	Species:	Mus musculus

Alignment Length:	256	Identity:	62/256 - (24%)
Similarity:	110/256 - (42%)	Gaps:	33/256 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 DDATNGRKKQKKNKKAKIRPLTMPVTSKDALMVLNELKGVTVDNMQIKRD---HEGKIMARVVVN 154
            ::.:||..|.:..|:   |....||..|:|||.|||:| ..:..|.:.:.   |....:..|.||
Mouse   120 EEGSNGHSKYRLKKR---RKTPGPVLPKNALMQLNEIK-PGLQYMLLSQTGPVHAPLFVMSVEVN 180

  Fly   155 SKKYEAEGSSVNSARNAACEKALQEIL--TTKMKAVLDGPGKSLE------SDEDDILEKMAS-- 209
            .:.:|..|.:...|:..|.||||:..:  ....:|.| ..|::|.      ||:.|..:.:.:
Mouse   181 GQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHL-AMGRTLSVNTDFTSDQADFPDTLFNGF 244

  Fly   210 ---------YAIHKLGEEWKTDDIDVATLYNDLKNKQTSVVEPKKPLPETW---KNMHPCMVLNY 262
                     :.:...|::..:...||:...:.:   ..|:.:|..|:|..:   ...:|.|:||.
Mouse   245 ETPDKSEPPFYVGSNGDDSFSSSGDVSLSASPV---PASLTQPPLPIPPPFPPPSGKNPVMILNE 306

  Fly   263 MRPQCTFIVSGGTGTNQNNTFSMSVCVDNCEFNAEGPSKKAARYKLSALVCNKLFGTDYPQ 323
            :||...:.....:|.:...:|.|||.||...|...|.:||.|:.:.:......:|.....|
Mouse   307 LRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALATVFNLHLDQ 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
blanks	NP_647966.1	None
Adarb1	XP_006513125.1	DSRM_RED1_rpt1	139..210	CDD:380724	23/71 (32%)
		DSRM_RED1_rpt2	296..365	CDD:380727	19/68 (28%)
		ADEAMc	386..772	CDD:214718
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167848503
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10910
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940