DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4835 and CG10725

DIOPT Version :9

Sequence 1:	NP_647965.3	Gene:	CG4835 / 38619	FlyBaseID:	FBgn0035607	Length:	1224	Species:	Drosophila melanogaster
Sequence 2:	NP_648647.1	Gene:	CG10725 / 39510	FlyBaseID:	FBgn0036362	Length:	269	Species:	Drosophila melanogaster

Alignment Length:	311	Identity:	65/311 - (20%)
Similarity:	105/311 - (33%)	Gaps:	101/311 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   499 DCSKYYLCLGGGQWTLA---PCIYGSYFDPSTGQCGPDVAPDACKPSQVTTTTTTTTTETTTTER 560
            :||||:||:.    .:|   .|....|||....:|.|.:..:.
  Fly    41 NCSKYFLCMN----EIAVPRECPTDYYFDARDQECVPLMEVEC---------------------- 79

  Fly   561 NTTPKSTATTTERTTTTVAPKTGICGGRNENENIAYPNNCTKYIVCVSPIPIAFFCPDGTFFSSK 625
                                 .|.|..|..: :..|...||||::|....|:...|.||..:::.
  Fly    80 ---------------------IGSCKNRGLS-SFCYDRTCTKYVLCFDGTPVIRQCSDGLQYNAL 122

  Fly   626 LEKCIDDWDE-SDCEGDQSTTTLEPGYTRPPPEPTMCTNSSRDTFPYPDNCQWF---IRCVDDYI 686
            .::|  |:.: .||..:                  :|:.::.     ||:..:.   .|| |.|.
  Fly   123 TDRC--DYPQYVDCVDN------------------LCSRNNN-----PDDIVFIPSKARC-DKYY 161

  Fly   687 YMMD----VCNC--GEYYDPITEKCGADVPSDACRWDYTSTTSTTSEPTTTTAV--TRPPPQKGP 743
            ..||    |.||  |..|:|.|:.|           |:.|..:.|.|......:  .|.||:...
  Fly   162 ICMDGLPQVQNCTSGLQYNPSTQSC-----------DFPSKVNCTVESLQRNILPFARAPPRLAD 215

  Fly   744 CDDVEDGA-LVAYPNDCSKYIQCDRPIAVAFECEKGDEFSVELGKCVDASL 793
            .:...:|| .:|:......|..|.....|..:|..|..|..:..:|.:..|
  Fly   216 IECPSEGAHFIAHQKRQDAYYYCLNGRGVTLDCTPGLVFDAKREECREPHL 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4835	NP_647965.3	CBM_14	51..103	CDD:279884
		CBM_14	185..237	CDD:279884
		CBM_14	273..322	CDD:279884
		CBM_14	393..444	CDD:279884
		CBM_14	485..539	CDD:279884	13/42 (31%)
		CBM_14	585..638	CDD:279884	14/53 (26%)
		CBM_14	661..714	CDD:279884	17/61 (28%)
		CBM_14	744..796	CDD:279884	11/51 (22%)
		CBM_14	914..962	CDD:279884
		CBM_14	1175..1212	CDD:279884
CG10725	NP_648647.1	CBM_14	35..73	CDD:279884	12/35 (34%)
		CBM_14	83..134	CDD:279884	14/53 (26%)
		CBM_14	150..192	CDD:279884	16/53 (30%)
		ChtBD2	216..264	CDD:214696	10/47 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444068
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D33909at6656
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23301
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950