DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4835 and CG33985

DIOPT Version :9

Sequence 1:	NP_647965.3	Gene:	CG4835 / 38619	FlyBaseID:	FBgn0035607	Length:	1224	Species:	Drosophila melanogaster
Sequence 2:	NP_001034018.1	Gene:	CG33985 / 3885639	FlyBaseID:	FBgn0053985	Length:	277	Species:	Drosophila melanogaster

Alignment Length:	339	Identity:	67/339 - (19%)
Similarity:	111/339 - (32%)	Gaps:	122/339 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   391 NDCKDEKDGTIFAYIGNCSEYLICKDNQVQMGHCPPNTLFNPDLLVCDEPDDVVCLGDRTTTPI- 454
            ::|.|..:.:......:|:.|:.|..::...|.|.....|:.|:.:|:...|:.|   ||.:.:
  Fly    26 DECNDGNNLSFVTSPKSCAHYIFCNGDESYDGECEDGEYFSQDMEMCEPMGDIDC---RTGSEVQ 87

  Fly   455 -PTTIPTTTTEKTTPTTT-TTTVATTLGPDQLCDGQELGASFSYPDDCSKYYLCLGGGQWTLAPC 517
             ..|..:::||.|:.::| :|.|.|||.|..:.                           ||.
  Fly    88 RENTTDSSSTEITSESSTISTVVITTLAPSAVV---------------------------TLR-- 123

  Fly   518 IYGSYFDPSTGQCGPDVAPDACKPSQVTTTTTTTTTETTTTERNTTPKSTATTTERTTTTVAPK- 581
                   ||..|.|..                                        :||:|:|.
  Fly   124 -------PSVNQSGAS----------------------------------------STTSVSPAI 141

  Fly   582 ----TGICGGRNENENIAY---PNNCTKYIVCVSPIPIAFFCPDGTFFSSKLEKCIDDWDESDCE 639
                |.:|...:....||.   .|:|:.|.:|...:.:...|.....|:|...|         |:
  Fly   142 EIIVTNVCPQLDNQSRIALLPNQNSCSDYYICYRGVALPMSCATSLHFNSLTGK---------CD 197

  Fly   640 GDQSTTTLEPGYTRPPPEPTMCTNSSRDTFPYPDNCQWFIRCVDDYIYMMDVCNCGEYYDPITEK 704
            ..::...|...|.  |.|  .|.....|.:|:.|||.:|.:|...|:.   |..|..:|.
  Fly   198 HPENVRCLAMTYN--PRE--QCKRHVIDVYPHSDNCNYFYQCRSGYLM---VQQCPFFYG----- 250

  Fly   705 CGADVPSDACRWDY 718
                       |||
  Fly   251 -----------WDY 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4835	NP_647965.3	CBM_14	51..103	CDD:279884
		CBM_14	185..237	CDD:279884
		CBM_14	273..322	CDD:279884
		CBM_14	393..444	CDD:279884	11/50 (22%)
		CBM_14	485..539	CDD:279884	6/53 (11%)
		CBM_14	585..638	CDD:279884	11/55 (20%)
		CBM_14	661..714	CDD:279884	12/52 (23%)
		CBM_14	744..796	CDD:279884
		CBM_14	914..962	CDD:279884
		CBM_14	1175..1212	CDD:279884
CG33985	NP_001034018.1	CBM_14	28..74	CDD:279884	10/45 (22%)
		CBM_14	160..202	CDD:279884	9/50 (18%)
		ChtBD2	215..259	CDD:214696	15/58 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D487374at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23301
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.020