Protein Alignment CG4835 and LOC1274513

DIOPT Version :10

• Sequence 1: NP_647965.3
• Gene: CG4835 / 38619
• FlyBaseID: FBgn0035607
• Length: 1224
• Species: Drosophila melanogaster
• Sequence 2: XP_061503039.1
• Gene: LOC1274513 / 1274513
• VectorBaseID: AGAMI1_006454
• Length: 1559
• Species: Anopheles gambiae
• Alignment Length: 1574
• Identity: 371/1574 - (23%)
• Similarity: 551/1574 - (35%)
• Gaps: 507/1574 - (32%)

  Fly    22 WQLNVLALPKIEPRHETCNNEQRYENQVMCEGKDFGALVPYPDNCSLFLVC----DCLYPTVKLC 82
            |...:|.|..:....|..        :..|:.:.|..   .|::|::|..|    |.|......|
Mosquito     8 WSAMLLTLAALAATAEAA--------KFQCQEEGFAV---DPNDCAVFYRCVQEGDSLTAYKFRC 61

  Fly    83 PANLWWDNKTQQCNYP---QAVECIYYSIE----TPEPTDGTTR---FTPEPTSSTQK------- 130
            .....:......|.:|   :..||.....|    .|||......   ..|||...|.:
Mosquito    62 GPGTVFSMNENVCVHPRDSEREECRETGNEIDGPAPEPEPAVPEPEPAAPEPEPQTMEQNEQEPM 126

  Fly   131 ----------------ITPEPTEPPSSTAKITTESTTGTSTEITSSTP----SSYLPTSSWDPPP 175
                            :.|| .:|.|:|.:.|:.:|||:|....|||.    |...|..:.|...
Mosquito   127 AMGNGELEQNGDAENSVNPE-AQPSSTTQRPTSAATTGSSGSSGSSTSQPAGSGMAPACTEDGFM 190

  Fly   176 APPGISDDY--CRNKEDGSVHYYPYDC-------QAYINCTYGWPVLNYCIEDKVFNKYLGICDT 231
            ..|.....:  |.:..:|....|.:.|       ....:|.:.|.|.:            |.|..
Mosquito   191 GDPNDCKKFYRCVSNGNGQFTRYEFRCGDGTVWDDNAGSCNHDWAVQD------------GRCGK 243

  Fly   232 PD-MADCEELPLPTTTTEMP---------PTSTTEEDVVCGPT--------PEGIEEDYCVPKG- 277
            |: .........|..|...|         |...:..:...||.        |:|....   |.|
Mosquito   244 PNGQGSSNGQHGPDETGSGPNGPEGNGSGPNGPSGPNGTDGPDGSSNGSNGPDGSSNG---PNGS 305

  Fly   278 NGFYEYPYNCSGYLACKNGCTDLDYCQPDKLFN--NWLHICDTPDSVRCDPLP------------ 328
            ||....|....|.....||....|  .|::..|  |..:..|.|:.......|
Mosquito   306 NGSNNGPSGPDGPNNGPNGPNGPD--GPNESSNGPNGPNGPDGPNGPGGSEGPNGPNGPEGPNGP 368

  Fly   329 -------FPTTPG---TTNKPTTPSVTTTPSITTTPSTP-------------TTLPSDGSTTEIH 370
                   .|..||   ..|.|..|..:..|..:..|:.|             ::..::.||....
Mosquito   369 SGPNGPDGPNGPGGPEGPNGPNGPEGSNGPEGSNGPNGPNGPNGPEGPNESNSSNGTEDSTAPGQ 433

  Fly   371 SSTT----EEIVTTTDGLPSDVDPNDCKDEKDGTIFAYIGNCSEYLICKDNQVQMGH-------- 423
            .|||    ::..|||...|:....::...|::| ...:..||.::..|.||    |:
Mosquito   434 QSTTVPPCQQQTTTTTQSPAVPAGSNGVCEQEG-FMEHPSNCKKFYRCVDN----GNGGYDRYEF 493

  Fly   424 -CPPNTLFNPDLLVCDEPDDV---VC-LGDRT-------------TTPIPTTIPTTTTEKTTPTT 470
             |.|.|:::.|:|.|:.|..|   .| .|..|             .|.:|   |..::.::.|:|
Mosquito   494 TCGPGTVWDNDILACNHPTSVQNSKCGTGGETASSQYPGSSSGPGNTYLP---PAQSSTESMPST 555

  Fly   471 TTTTVATTLGPDQLCDGQELGASFSYPDDCSKYYLCLGGGQWTLAPCIYGSYFDPSTGQCGPDVA 535
            |..|: ::|.|:.|..|....||.......|           |.|        .|.|.|...:.|
Mosquito   556 TEQTM-SSLEPESLTTGATDAASQETTSSTS-----------TTA--------QPETAQSTTEAA 600

  Fly   536 -PDACKPSQVTTTTTTTTTETTTTERNTTPKSTATTTE---RTTTTVA----------------P 580
             |:....:|..||.|...| |..::...|..:...|||   :|:||||                |
Mosquito   601 KPETSSSAQEQTTETQNQT-TEASKEEATSNAQEQTTESQSQTSTTVAGDSSTTPEGATETSTMP 664

  Fly   581 KTGICGGRNENENI-AYPNNCTKYIVCVSP-----IPIAFFCPDGTFFSSKLEKCIDDWDESDCE 639
            .:..|    ::|.. .:|.||..:..||..     ....|.|.:||.:....:.|..:::..:|.
Mosquito   665 SSEGC----DSEGFKPHPTNCKMFYRCVDNGKGGYTKYEFTCSEGTGWDESKQACNYEYEIPNCG 725

  Fly   640 GDQSTTTLEPGYTRPP---PEPT---MCTNSSRDTFPYPDNCQWFIRCVDDYIYMMDVCNCGEYY 698
            .|           |||   |||:   |.|.:|..|                 ....||...|.
Mosquito   726 AD-----------RPPEPEPEPSGTDMTTGASEGT-----------------TATTDVATDGT-- 760

  Fly   699 DPITEKCGA--------------------------------DVPSDACRWDYTSTTSTTSEPTTT 731
            .|..|...|                                ..|||:.    ||.:|:..|.|||
Mosquito   761 TPAQESTTAKQETTTTAAQEATTTSANQQTTTTDQANQETTTAPSDST----TSASSSAQETTTT 821

  Fly   732 TA---------------------------------------------------VTRPPPQKGPCD 745
            .|                                                   .|......|.|
Mosquito   822 GATGQEMTTSNEMASEMTTVQGQEMTTAGGATTTTGSETTAAGSEMTTESSQQTTTMGSSSGEC- 885

  Fly   746 DVEDGALVAYPNDCSKYIQC-----------DRPIAVAFECEKGDEFSVELGKCVDASLA----- 794
             .|:| .:..|:||.|:.:|           |      |.|.:|..:...|..|...::.
Mosquito   886 -TEEG-FMGSPDDCRKFYRCVDNGKGGFNKYD------FTCGEGTAWDQALQTCNHENVVEMCGG 942

  Fly   795 -------NCSITTTAKPSESTTTPRDGEGSTTPSEPSTGSSTESSTESTT--EPSTESTTESTT- 849
                   |.:.|.::..|.:|||      |||.|..:|.:||.::|.|||  .|||.|||.:||
Mosquito   943 QTGNTSNNTNQTQSSSTSSTTTT------STTASTTTTTTSTTTTTTSTTTKAPSTTSTTTTTTT 1001

  Fly   850 --ESTTESTTESSTGQSTETTESSTVLSTDTSESPSTISTPPSS---------TTMEPGTTN--P 901
              .|||.|||.:.| |...||..||..:|.:|..|||.|:..||         ::.||.||.  .
Mosquito  1002 QAPSTTASTTTTQT-QPPSTTTQSTTSTTTSSAQPSTTSSSSSSSSATTQSMQSSSEPTTTERMK 1065

  Fly   902 EASTTEKPADGICEGKTDDSLVPYPRNCSKYIKCQYPIPVG-------YDCPDGLEFSPTELTCM 959
            .:|::..|.:  |   |:....|.|.:|:|:.:|.....:|       :|||:|..:.|...||.
Mosquito  1066 ASSSSSTPVN--C---TEAGFFPNPDDCTKFYRCVDWDGMGENFSVFHFDCPEGTIWDPAVNTCN 1125

  Fly   960 DPELA----GCSTKLTTPGLTTLSTEASSTPVTTVSTTPEATTTEMSTTPKTTTTESTTIST--- 1017
            ..:..    .|| |...|.    :||:::...|:|:..|.:||.....|.....||:||.::
Mosquito  1126 HEDSVQPPRNCS-KSAPPE----TTESNAESTTSVTEEPGSTTEGAQMTTTAQQTEATTAASGQQ 1185

  Fly  1018 -TTTDSTTPQTTTTESTTSKTTTTESTIISTTPTTTEPTTPKTTTTESTTIPTTTTESTTATTT- 1080
             |||||.:.:||   :...:.|||:..:::||.|..:.||  |...:.||....|||.:..|||
Mosquito  1186 ETTTDSMSTETT---AAPKEETTTQQQMMTTTDTAAQETT--TMAGQETTQAAATTEGSQETTTM 1245

  Fly  1081 -PQTTTT----ESTTISTTPKTTTT----ESTTVSTTPTTT----ESTTISTTPTTT----EPTT 1128
             .|.|||    ||||  |..:.|||    ||||::...|||    |:||::...|||    |.||
Mosquito  1246 AAQETTTMAAQESTT--TAAQETTTMGAQESTTMAAQETTTMAAQETTTMAAQETTTMAAQETTT 1308

  Fly  1129 V----STT-----------PKTTTTEST---TVTT------TTEST----TTVSTPTTLDPYTPN 1165
            :    |||           |:.|||.|:   .:||      |||:.    ||....::.:|.:..
Mosquito  1309 MAAQESTTGSNQQETTTASPQETTTSSSGEQEMTTMGQSEMTTEAAGQEQTTEGMESSTEPASQE 1373

  Fly  1166 ICCGQALGTLLP----------------YPNDCGRYVVC-------DYPIPYAVDCDEGTIFDDN 1207
             |....:.:..|                :|.:|..:..|       ||.| ....|...|::.::
Mosquito  1374 -CPAGCMSSCPPVDEDQDRFVCPTGFKRHPKNCNLFYQCTEKPNSYDYSI-VVFSCPNDTVYQED 1436

  Fly  1208 LLQCTSVP--NERC 1219
            ..|||:..  ::||
Mosquito  1437 RTQCTAPAEGDDRC 1450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4835	NP_647965.3	CBM_14	51..103	CDD:426342	11/58 (19%)
		CBM_14	185..237	CDD:426342	10/59 (17%)
		CBM_14	273..322	CDD:426342	14/51 (27%)
		CBM_14	393..444	CDD:426342	16/62 (26%)
		CBM_14	485..539	CDD:426342	11/54 (20%)
		CBM_14	585..638	CDD:426342	12/58 (21%)
		CBM_14	661..714	CDD:426342	12/84 (14%)
		CBM_14	744..796	CDD:426342	14/74 (19%)
		CBM_14	914..962	CDD:426342	15/54 (28%)
		CBM_14	1175..1212	CDD:426342	10/59 (17%)
LOC1274513	XP_061503039.1	None