DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir64a and GLR3.4

DIOPT Version :9

Sequence 1:	NP_647962.1	Gene:	Ir64a / 38616	FlyBaseID:	FBgn0035604	Length:	859	Species:	Drosophila melanogaster
Sequence 2:	NP_001030971.1	Gene:	GLR3.4 / 839268	AraportID:	AT1G05200	Length:	959	Species:	Arabidopsis thaliana

Alignment Length:	473	Identity:	72/473 - (15%)
Similarity:	133/473 - (28%)	Gaps:	204/473 - (43%)

- Green bases have known domain annotations that are detailed below.

  Fly   373 KNGRFDGMIGALIRNETDIGGAPIFYWLERHKWIDVAGRSWSSRPCFIFRHP------------R 425
            :|..:|.::..::.:..|:....|.....|.:::|             |..|            :
plant   548 RNPSYDNLVNEVVADNFDVAVGDITIVTNRTRYVD-------------FTQPFIESGLVVVAPVK 599

  Fly   426 STQKDRIVFLQPFTNDVWILIVGCGVLTVFILWFLTTIEWKLVPHDGSALIKPKGGAPPRHHYQQ 490
            ..:.....||:|||.::|.:..|..:....::|.|                        .|.:.|
plant   600 EAKSSPWSFLKPFTIEMWAVTGGFFLFVGAMVWIL------------------------EHRFNQ 640

  Fly   491 QQQQEQVEAPVRPITAVSVVVSKEKVEEKQEEYEDSTPIDAGTLWQRCYQKLNKYIKDRKAKQKK 555
                                                                          :.:
plant   641 --------------------------------------------------------------EFR 643

  Fly   556 APERVGLFLESVLFFVGIICQQGLGFSTSFVS---------GRCIVITSLLFSFCIYQFYSASIV 611
            .|.|..|.  ::.:|         .|||.|.|         ||.::|..|.....|...|:||:.
plant   644 GPPRRQLI--TIFWF---------SFSTMFFSHRENTVSSLGRFVLIIWLFVVLIINSSYTASLT 697

  Fly   612 GTL-LMEKPKTIKTLSDLVHSSLKVGMEDILYNRDYFLH-----------TKDPVSMELYAKKIT 664
            ..| :.:....|:.:..||.|:..:|::|..:.|:|.::           .||.   |.|...:.
plant   698 SILTIRQLTSRIEGIDSLVTSNEPIGVQDGTFARNYLINELNILPSRIVPLKDE---EQYLSALQ 759

  Fly   665 SVPTTKENEADEDEPVDPNPVSTDPAKSYRDIVHSHETGAHAKDNAASNWLDPETGLLRHLGFAF 729
            ..|......|..||......:.|:....:|.:         .::...:.|           ||||
plant   760 RGPNAGGVAAIVDELPYIEVLLTNSNCKFRTV---------GQEFTRTGW-----------GFAF 804

  Fly   730 HVDVAAAYKIIAETFSEQDICDLTEVSMFPPQKTVSIMQKNSPMRKVISYGLRRVTETGILTYHF 794
                                                  |::||:...:|..:.:::|.|.|....
plant   805 --------------------------------------QRDSPLAVDMSTAILQLSEEGELEKIH 831

  Fly   795 NVWHSRKPPCVKKIETSD 812
            ..|.:.|..|..:|..|:
plant   832 RKWLNYKHECSMQISNSE 849

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir64a	NP_647962.1	Periplasmic_Binding_Protein_Type_2	351..>465	CDD:304360	17/103 (17%)
Ir64a	NP_647962.1	Lig_chan	563..828	CDD:278489	50/271 (18%)
GLR3.4	NP_001030971.1	PBP1_GABAb_receptor_plant	62..450	CDD:380645
		Periplasmic_Binding_Protein_Type_2	<518..591	CDD:389745	8/55 (15%)
		Lig_chan	615..869	CDD:365843	59/393 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000