DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir64a and GLR2.5

DIOPT Version :9

Sequence 1:	NP_647962.1	Gene:	Ir64a / 38616	FlyBaseID:	FBgn0035604	Length:	859	Species:	Drosophila melanogaster
Sequence 2:	NP_001332219.1	Gene:	GLR2.5 / 830991	AraportID:	AT5G11210	Length:	918	Species:	Arabidopsis thaliana

Alignment Length:	521	Identity:	91/521 - (17%)
Similarity:	156/521 - (29%)	Gaps:	178/521 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   355 DMFNWTFVLSR---TTSWGYV--------KNGRFDGMIGALIRNETD--IGGAPIFYWLERHKWI 406
            |:||  .|:|:   ..|:.|:        ..|.:|.|:..:...|.|  :|...|.  ..|..::
plant   491 DVFN--TVMSQMPYAVSYEYIPFDTPDGKPRGSYDEMVYNVFLGEFDGAVGDTTIL--ANRSHYV 551

  Fly   407 DVAGRSWSSRPCFIFRHPRSTQKDRIVFLQPFTNDVWILIVGCGVLTVFILWFLTTIEWKLVPHD 471
            |.|.....:...|:.......:|...|||:|.|.::|::.....:....::|..
plant   552 DFALPYSETGIVFLVPVKDGKEKGEWVFLKPLTKELWLVTAASFLYIGIMVWIF----------- 605

  Fly   472 GSALIKPKGGAPPRHHYQQQQQQEQVEAPVRPITAVSVVVSKEKVEEKQEEYEDSTPIDAGTLWQ 536
                           .||                             ..||:.:...||.
plant   606 ---------------EYQ-----------------------------ADEEFREQMIIDK----- 621

  Fly   537 RCYQKLNKYIKDRKAKQKKAPERVGLFLESVLFFVGIICQQGLGFSTSFVS---------GRCIV 592
                                       :.||.:|         .|||.|.:         .|.:|
plant   622 ---------------------------ISSVFYF---------SFSTLFFAHRRPSESFFTRVLV 650

  Fly   593 ITSLLFSFCIYQFYSASIVGTLLMEKPK-TIKTLSDLVHSSLKVGMEDILYNRDYFLHTKDPVSM 656
            :........:.|.|:|::...|.:::.: |::.:.||..|.:.:|     |....|...:
plant   651 VVWCFVLLILTQSYTATLTSMLTVQELRPTVRHMDDLRKSGVNIG-----YQTGSFTFER----- 705

  Fly   657 ELYAKKITSVPTTKENEADEDEPVDPNPVSTDPAKSYRDIVHSHETGAHAKDNAASNWLDPETGL 721
                        .|:...||..           .|:|.......|...|...|...:....|...
plant   706 ------------LKQMRFDESR-----------LKTYNSPEEMRELFLHKSSNGGIDAAFDEVAY 747

  Fly   722 LRHLGFAFHVDVAAAYKIIAETFSEQDICDLTEVSMFPPQKTVSIMQKNSPMRKVISYGLRRVTE 786
            ::    .|.....:.|.||..||.....     ...||         ..||:...||..:..:||
plant   748 IK----LFMAKYCSEYSIIEPTFKADGF-----GFAFP---------LGSPLVSDISRQILNITE 794

  Fly   787 TGILTYHFNVWHSRKPPCVKKIETSDLHVDMDTVS-SALLILLF--SYAITLMILGTEILYSKWH 848
            ...:....|.|...:..|:.. .|||..:.:|..| .||.:::|  |..:.|::|.:.....:.|
plant   795 GDAMKAIENKWFLGEKHCLDS-TTSDSPIQLDHHSFEALFLIVFVVSVILLLLMLASRGYQERQH 858

  Fly   849 N 849
            |
plant   859 N 859

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir64a	NP_647962.1	Periplasmic_Binding_Protein_Type_2	351..>465	CDD:304360	26/122 (21%)
Ir64a	NP_647962.1	Lig_chan	563..828	CDD:278489	53/275 (19%)
GLR2.5	NP_001332219.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910