DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir64a and GLUR2

DIOPT Version :9

Sequence 1:	NP_647962.1	Gene:	Ir64a / 38616	FlyBaseID:	FBgn0035604	Length:	859	Species:	Drosophila melanogaster
Sequence 2:	NP_001320141.1	Gene:	GLUR2 / 829682	AraportID:	AT4G35290	Length:	912	Species:	Arabidopsis thaliana

Alignment Length:	349	Identity:	66/349 - (18%)
Similarity:	118/349 - (33%)	Gaps:	120/349 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   427 TQKDRIV-FLQPFTNDVWILIVGCGVLTVFILWFLTTIEWKLVPHDGSALIKPKGGAPPRHHYQQ 490
            |::.||| |.||:        :..|::.|..:..|....|        |.::|
plant   549 TKRTRIVDFTQPY--------IESGLVVVAPVTKLNDTPW--------AFLRP------------ 585

  Fly   491 QQQQEQVEAPVRPITAVSVVVSKEKVEEKQEEYEDSTPIDAGTLWQRCYQKLNKYIKDRKAKQKK 555
                  ...|:..:||...::                   .|::......::|...:....||
plant   586 ------FTPPMWAVTAAFFLI-------------------VGSVIWILEHRINDEFRGPPRKQ-- 623

  Fly   556 APERVGLFLESVLFFVGIICQQGLGFSTSFVS---------GRCIVITSLLFSFCIYQFYSASIV 611
                    :.::|:|         .|||.|.|         ||.:::..|.....|...|:||:.
plant   624 --------IVTILWF---------SFSTMFFSHRENTVSTLGRAVLLIWLFVVLIITSSYTASLT 671

  Fly   612 GTLLMEKPKT-IKTLSDLVHSSLKVGMEDILYNRDYFLHTKDPVSMELYAKKITSVPTTKENEAD 675
            ..|.:::..: |:.:..|:.||.:||.:...|..:|.:.     .:.:...::..:.:.||..|.
plant   672 SILTVQQLNSPIRGVDTLISSSGRVGFQVGSYAENYMID-----ELNIARSRLVPLGSPKEYAAA 731

  Fly   676 EDEP-----VDPNPVSTDPAKSYRDIVHSHETG--AHAKDNAASNWLDPETGLLRHLGFAF---- 729
            ....     ||..|        |.|:..|...|  ...::...|.|           ||||
plant   732 LQNGTVAAIVDERP--------YVDLFLSEFCGFAIRGQEFTRSGW-----------GFAFPRDS 777

  Fly   730 --HVDVAAAYKIIAETFSEQDICD 751
              .:|::.|...::||...|.|.|
plant   778 PLAIDMSTAILGLSETGQLQKIHD 801

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir64a	NP_647962.1	Periplasmic_Binding_Protein_Type_2	351..>465	CDD:304360	10/38 (26%)
Ir64a	NP_647962.1	Lig_chan	563..828	CDD:278489	46/212 (22%)
GLUR2	NP_001320141.1	PBP1_GABAb_receptor_plant	31..422	CDD:380645
		GluR_Plant	466..804	CDD:270404	66/349 (19%)
		Lig_chan	590..840	CDD:395014	52/274 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000