DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir64a and GLR2.7

DIOPT Version :9

Sequence 1:	NP_647962.1	Gene:	Ir64a / 38616	FlyBaseID:	FBgn0035604	Length:	859	Species:	Drosophila melanogaster
Sequence 2:	NP_180476.3	Gene:	GLR2.7 / 817460	AraportID:	AT2G29120	Length:	952	Species:	Arabidopsis thaliana

Alignment Length:	436	Identity:	76/436 - (17%)
Similarity:	131/436 - (30%)	Gaps:	163/436 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   424 PRSTQKDRIVFLQPFTNDVWILIVGCGVLTVFILWFLTTIEWKLVPHDGSALIKPKGGAPPRHHY 488
            |....|:..|||:|::.|:|:......|...||:|.|            ...:......||.|
plant   567 PLKDNKNTWVFLRPWSLDLWVTTACFFVFIGFIVWIL------------EHRVNTDFRGPPHH-- 617

  Fly   489 QQQQQQEQVEAPVRPITAVSVVVSKEKVEEKQEEYEDSTPIDAGTLWQRCYQKLNKYIKDRKAKQ 553
                                                     ..||.:...:..:|      .|.:
plant   618 -----------------------------------------QIGTSFWFAFSTMN------FAHR 635

  Fly   554 KKAPERVGLFLESVLFFVGIICQQGLGFSTSFVSGRCIVITSLLFSFCIYQFYSASIVG--TLLM 616
            :|....:..|:..|..||.::                           :.|.|:|::..  |:.:
plant   636 EKVVSNLARFVVLVWCFVVLV---------------------------LIQSYTANLTSFFTVKL 673

  Fly   617 EKPKTIKTLSDLVHSSLKVGMEDILYNRDYFLHTKDPVSMELYAKKITSVPTTKENEADEDEPVD 681
            .:| |:....||:..:..:|     |.|..|:.       ||          .|....||.: :.
plant   674 LQP-TVTNWKDLIKFNKNIG-----YQRGTFVR-------EL----------LKSQGFDESQ-LK 714

  Fly   682 P--NPVSTDPAKSYRDIVHSHETGAHAK-----DNAASNWLDPETGLLRHLGFAFHVDVAAAYKI 739
            |  :.|..|...|...|..|.:..|:.|     :::....::|.   .:..||.|
plant   715 PFGSAVECDELFSNGTITASFDEVAYIKVILSQNSSKYTMVEPS---FKTAGFGF---------- 766

  Fly   740 IAETFSEQDICDLTEVSMFPPQKTVSIMQKNSPMRKVISYGLRRVTETGILTYHFNVWHSRKPPC 804
                             :||         |.||:...:|..:..||:...:.:..|.|. :||..
plant   767 -----------------VFP---------KKSPLTDDVSRAILNVTQGEEMQHIENKWF-KKPNN 804

  Fly   805 VKKIET--SDLHVDMDTVSSALLILLFSYAITLMILGTEILYSKWH 848
            ...:.|  |..|:.:.:.....||...:..:.|:|.....||...|
plant   805 CPDLNTSLSSNHLSLSSFWGLFLIAGIASFLALLIFVANFLYEHKH 850

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir64a	NP_647962.1	Periplasmic_Binding_Protein_Type_2	351..>465	CDD:304360	13/40 (33%)
Ir64a	NP_647962.1	Lig_chan	563..828	CDD:278489	50/275 (18%)
GLR2.7	NP_180476.3	PBP1_GABAb_receptor	40..421	CDD:107361
		ANF_receptor	54..405	CDD:279440
		GluR_Plant	460..799	CDD:270404	63/382 (16%)
		Lig_chan	584..832	CDD:278489	65/399 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000