DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir64a and Ir7d

DIOPT Version :9

Sequence 1:	NP_647962.1	Gene:	Ir64a / 38616	FlyBaseID:	FBgn0035604	Length:	859	Species:	Drosophila melanogaster
Sequence 2:	NP_001138175.1	Gene:	Ir7d / 7354416	FlyBaseID:	FBgn0259190	Length:	594	Species:	Drosophila melanogaster

Alignment Length:	428	Identity:	80/428 - (18%)
Similarity:	135/428 - (31%)	Gaps:	161/428 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   523 YEDSTPIDA-----GTLWQRCYQKLN----------------------------KYIKDRKAK-- 552
            ::.|.|:|.     |.|.:...:|:|                            |.:::|:|.
  Fly   227 WKSSDPMDGLDGLDGLLLRIVARKMNFTLKLIPNEPNGLIGGSSFMNGTFTGAYKMLRERRANIT 291

  Fly   553 ---QKKAPERVGLFLE-----SVLFFVGIICQQGLGFS----------------TSFVSGRCIVI 593
               ....||| ..|||     |.:.:: |:.|...|:|                .|.:.|...::
  Fly   292 IGCAACTPER-STFLEATSPYSQMSYI-IVLQARGGYSIYEVMLFPFEKYTWLLLSTILGLHWIV 354

  Fly   594 TS------------LLFSFCIYQFYSASIVGTLLMEKPKTIKTLSDLVHSSLKVGMEDILYNRDY 646
            .|            :|:.|.|...|.||:. ..:...|  :|.....:..:|..|...|..:..|
  Fly   355 GSRWRMPSPILAGWMLWIFVIRASYEASVF-NFIQNSP--VKPSPRTLDQALSGGFRFITDHASY 416

  Fly   647 FLHTKDPVSMELYAKKITSVPTTKENEADEDEPVDP-NPVSTDPAKSYRDIVHSHETGAHAKDNA 710
            .:..|.|   ....|.:.|.          .:|||. :.:...|.|          |||....
  Fly   417 RMTLKIP---SFQGKTLISA----------GQPVDVFDALLKAPWK----------TGAFTSR-- 456

  Fly   711 ASNWLDPETGLLRHLGFAFHVDVAAAYK-------IIAETFSEQDICDLTEVSMFPPQKTVSIMQ 768
                             ||..|....::       |:||...:..:|      |:.|..:....:
  Fly   457 -----------------AFLADHLVRHRKHRNQLVILAEKIVDNMLC------MYFPHGSYFAWE 498

  Fly   769 KNSPMRKVISYGLRRVTETGILTYHFNV--WHSRKPPCV------KKIETSDLHV------DMDT 819
            .|..:..:.|:        ||..:|..:  | ...|...      |:|.:|...|      .|..
  Fly   499 INKLLFNMRSF--------GIFQHHSQILAW-DNLPTTTDTDTPGKRIHSSTESVATGFAESMSF 554

  Fly   820 VSSALLILLFSYAITLMILGTEILYSKWHNRIQLKWVG 857
            |.:||..|:.:..|::::.|.|:|..:.|      |.|
  Fly   555 VVAALNCLMGALCISIVVFGLELLSRRRH------WTG 586

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir64a	NP_647962.1	Periplasmic_Binding_Protein_Type_2	351..>465	CDD:304360
Ir64a	NP_647962.1	Lig_chan	563..828	CDD:278489	59/319 (18%)
Ir7d	NP_001138175.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462959
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.830