Protein Alignment Ir64a and grin3a

DIOPT Version :10

• Sequence 1: NP_647962.1
• Gene: Ir64a / 38616
• FlyBaseID: FBgn0035604
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: XP_073770471.1
• Gene: grin3a / 564832
• ZFINID: ZDB-GENE-130530-780
• Length: 1117
• Species: Danio rerio
• Alignment Length: 1014
• Identity: 177/1014 - (17%)
• Similarity: 318/1014 - (31%)
• Gaps: 346/1014 - (34%)

  Fly     6 LVFLP-----LSCQG-------LPEHELLE--LELDYGLAE--------------PQRTSLLQS- 41
            :||||     |:.:.       ||.:..||  :.::.||.|              ....|.|||
Zfish   125 VVFLPRDSVLLASESLNRVAGLLPYNLTLEIVMAVEAGLGELPAFSFSSSSTPACADPVSFLQSV 189

  Fly    42 ---------SLILQFSQDYKHIPRITYF--TCQKP-----------------HLQTPNQIPNAAE 78
                     |.|:.|.|:...:.::.:.  |.|.|                 |.|...|.|..::
Zfish   190 CHTVIVQGVSAIISFPQNRDELVKLEFIASTLQIPVISVVQSEFQRQTQNLLHFQMAMQNPQTSQ 254

  Fly    79 HRDAFAAKNFQLIKSLYESELFVRIVLLDVLAQSPTSGRPNRPGNGPTGGFSQTPSQAQSNSEWL 143
                     ..||.||.....:..:.|  |:.|..              ..|.......:||::.
Zfish   255 ---------ANLIFSLLSMNNWFDVSL--VMCQQM--------------NISDFVFLLHNNSKFH 294

  Fly   144 EGVL-------------------RMEALRQ--IAVVDLACGA--VSRRFLELASAKMLYSEKFHW 185
            .|.:                   ::|:::.  ..:|...|..  :.|.|..:|...::..: :||
Zfish   295 LGTVLKISTNSSSKNDFHIFLQAQLESIKDSTSTLVTFGCDIRDIRRIFTTIAKFGLILPD-YHW 358

  Fly   186 LL-----IEDFAWHGRTQTAEGSGKRDDGEMEEEEPPGQQI-------QATDDEDL---PSIESF 235
            ::     :|:....|........|:..:..::.......::       .||....|   |...:.
Zfish   359 IIGDSQNVEELRTEGLPMGLLAHGRMGEPSLDHYVQDALELVARAVGSAATVSPQLALIPGTTNC 423

  Fly   236 LGGMNLYMNTELTLAKR----------------------MSEAAHYTLFDVWNPGLNYGGHVNLT 278
            |..:.....|..|...|                      :||:.|:    :||...:..|....|
Zfish   424 LARLEAKNLTSGTFLSRYMASTSFDGLSGCISVQEESTIISESHHF----IWNLQHDPIGKPMWT 484

  Fly   279 EIGSFTPTEGIQLH-TW-----------FRTTSTVRRRMD--MQH---------------ARVRC 314
            .:||:...:.:..: .|           :|.:|.:..|:.  ::|               |...|
Zfish   485 RLGSWKHGKVVMDYGVWPNKRRSQPGADWRHSSRLHLRVVTLVEHPFVFTRDVDDEGLCPAGQLC 549

  Fly   315 MVVVTNKNMTGTLMYYLTHTMSGHIDTM--------NRFNFNLL-MAVRDM-FNWTFVLSRTTSW 369
            :..:||..   .|:..|...:.|..||:        ..:..:|| ....|| |::...:.....:
Zfish   550 LDPLTNDT---ALLESLFQGLQGANDTVPLEFKKCCYGYCIDLLEKLAEDMGFDFDLYIVGDGKY 611

  Fly   370 GYVKNGRFDGMIGALIRNETDIGGAPIFYWLERHKWIDVAGRSWSSRPCFIFRHPRSTQKDRIVF 434
            |..||||:.|::|.|:.....:..........|.:.||.....:|:....:.| .|.|......|
Zfish   612 GAYKNGRWTGLVGDLMSGAAHLAVTSFSINSARSQVIDFTSPFFSTSLGILVR-TRDTAAPIGAF 675

  Fly   435 LQPFTNDVWI-LIVGCGVLTVFILWFLTTIEWKLVPHDGSALIKPKGGAPPRHHYQQQQQQEQVE 498
            :.|....:|: :.|...|..|    |||..|||          .|.|..|
Zfish   676 MWPLHWSMWLGIFVSLHVTAV----FLTLYEWK----------SPFGMTP--------------- 711

  Fly   499 APVRPITAVSVVVSKEKVEEKQEEYEDSTPIDAGTLWQRCYQKLNKYIKDRKAKQKKAPERVGLF 563
                            :...:...:..|:.::.      ||
Zfish   712 ----------------RGRNRDRVFSFSSALNV------CY------------------------ 730

  Fly   564 LESVLFFVGIICQQGLGFSTSFVSGRCIV---ITSLLFSFCIY--QFYSASIVGTLLMEKPKTIK 623
              ::||          |.:.:....:|..   :.:|...||::  ..|:|::...::.|  ||.:
Zfish   731 --AILF----------GRTAAIKPPKCWTGRFLMNLWAIFCLFCLSTYTANLAAVMVGE--KTYE 781

  Fly   624 TLSDLVHSSLKVGMEDILYNRDYFLHTKDPVSMELYAKKITSVPTTKENEADEDEPVDPNPVSTD 688
            .||.:....|....:...:.      |....|.|.|.||  |.|...|.....:.|..|:.:.
Zfish   782 QLSGIHDPKLHHPSQGFRFG------TVRESSAEDYVKK--SFPEMHEYMRRYNAPTTPDGID-- 836

  Fly   689 PAKSYRDIVHSHETGAHAKDNAASNWLDPETGLLRHLGFAFHVDVAAA-YKIIAETFSEQDICDL 752
                            |.||:...  ||           ||.:|.|.. |::..:
Zfish   837 ----------------HLKDDPQK--LD-----------AFIMDKALLDYEVSID---------- 862

  Fly   753 TEVSMFPPQKTVSI------MQKNSPMRKVISYGLRRVTETGILTYHFNVWHSRKPPCVKK--IE 809
            .:..|....|..:|      :::|||:...||..:.:....|.:....:.|: :..||.|:  ..
Zfish   863 ADCKMLTVGKPFAIEGYGIGLKQNSPLTSNISELVSQYKSDGFMDMLHDKWY-KVVPCGKRSFAV 926

  Fly   810 TSDLHVDMDTVSSALLILLFSYAITLM-ILGTEILYSKW 847
            |..|.:.:...|...::|....|::|: .||..|:: :|
Zfish   927 TETLQMGIKHFSGLFVMLCVGVALSLLTTLGEHIVH-RW 964

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir64a	NP_647962.1	Periplasmic_Binding_Protein_Type_2	351..>465	CDD:473866	27/115 (23%)
		Lig_chan	563..828	CDD:459656	52/278 (19%)
grin3a	XP_073770471.1	None