Protein Alignment Ir64a and grin2aa

DIOPT Version :9

• Sequence 1: NP_647962.1
• Gene: Ir64a / 38616
• FlyBaseID: FBgn0035604
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: XP_021329529.1
• Gene: grin2aa / 563297
• ZFINID: ZDB-GENE-070424-129
• Length: 1460
• Species: Danio rerio
• Alignment Length: 799
• Identity: 134/799 - (16%)
• Similarity: 239/799 - (29%)
• Gaps: 285/799 - (35%)

  Fly   109 LAQSPTSGRPN-RPGNGPTGGFSQTPSQAQSNSEW---LEGVLRMEALRQIAVVDLACGAVSRRF 169
            :..|.|:|.|. .|...|:|..|      .|..:|   ||..:|    ..:.::..|..|:...|
Zfish   253 IVPSLTTGNPEITPDTFPSGMIS------VSYDDWDYPLEARVR----DGLGIITTAAAAMLEEF 307

  Fly   170 LELASAKMLYSEKFHWLLIEDFAWHGRTQTAEGSGK----RDDGEMEEEEPPGQQIQATDDEDLP 230
            .::..||.....:.....:...|.|.........||    .:||  .:..|....|....|.:..
Zfish   308 GDIPEAKTSCYGQMEKTKLPPSALHKYMMNVTWDGKDLSFTEDG--YQVHPKLVVIVLNKDREWE 370

  Fly   231 SIESFLGGMNLYMNTELTLAKRMSEAAHYTLFDVWNPGLNYGG-------HVNLT--EIGSFTPT 286
            .       |..:.|..|||.           :.|| |..|..|       |:.:.  |...|...
Zfish   371 K-------MGKWENQSLTLK-----------YPVW-PRFNSFGDAETDDNHLTIVTLEEKPFVIV 416

  Fly   287 EGIQLHTWFRTTSTVRRRMDMQHARVRCMVVVTNKNMT---GTLMYYLTHTMSGHIDTMNRFNFN 348
            |.::     |.|.|..|.      .|.|...:.: |.|   ||   |:.....|       |..:
Zfish   417 ENVE-----RLTGTCMRN------SVPCRKHIKD-NTTEGGGT---YIKKCCKG-------FCID 459

  Fly   349 LLMAVRDMFNWTFVLSRTTSWGYVK--NGRFDGMIGALIRNETDIGGAPIFYWLERHKWIDVAGR 411
            :|..:.....:|:.|...|:..:.|  |..::||:|.::..:..:....:....||.:.||.:..
Zfish   460 ILKKIARNVKFTYDLYLVTNGKHGKKINNVWNGMVGEVVNKKAVMAVGSLTINEERSEVIDFSVP 524

  Fly   412 SWSSRPCFIFRHPRSTQKDRIVFLQPFTNDVW----ILIVGCGVLTVFI---------------- 456
            ...:....:......|.... .||:||:..||    ::::....:.||:
Zfish   525 FVETGISVMVSRSNGTVSPS-AFLEPFSASVWVMMFVMLLLVTAMAVFMFEYISPLGFNRNLAQG 588

  Fly   457 -------------LWFLTTIEWKLVPHDGSALIKPKG---------------------------- 480
                         :|.|    |.||.::...:..|||
Zfish   589 KDPHGPSFTMGKAVWLL----WGLVFNNSVPVQNPKGTTSKFIVSVWAFFAVIFLASYTANLAAF 649

  Fly   481 --------------------------------------------GAPPRHHYQQQQQQE------ 495
                                                        ..|..|.|..:..|.
Zfish   650 MIQEEFVDQVTGLSDKKFQSPYSYSPPFRFGTVPNGSTERNIRKNYPDMHQYMVKYHQTGVNDAL 714

  Fly   496 ------QVEAPVRPITAVSVVVSKE---KVEEKQEEYEDST-----PIDAGTLWQR--------- 537
                  :::|.:.....::.:..::   |:......|..:|     .:..|:||:|
Zfish   715 VSLKTGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGYIFATTGYGIALQKGSLWKRPVDLAILAI 779

  Fly   538 -----------------CYQKLNKYIKDRKAKQKKAPERVGLFLESVLFFVGIICQQGLGFSTSF 585
                             |:.:.|:.:    :.|.......|:|..       :....||...| |
Zfish   780 IGDGEMEELEAQWLTGICHNEKNEVM----SSQLDVDNMAGVFYM-------LATAMGLSLIT-F 832

  Fly   586 V-------------SGRCIVITSLLFSF------CIYQF------------YSASIVGTLLMEKP 619
            |             :|.|.....||||.      ||:..            :|.......|::..
Zfish   833 VWEHLFYWRLRYCFTGVCSGTPGLLFSISRGIWSCIHGVHIDMKKKSSDLDFSPQSNMLKLIKSA 897

  Fly   620 KTIKTLSDLVHS---SLKVGMEDILYNRDYFLHTKDPVSMELYAKKITSVPTTKENEADEDEPVD 681
            |.:..:::|..|   |.|.|.|        |:|:..|:.|::.|:|...:.|...:.|.:|...|
Zfish   898 KQMTNMTNLSGSRINSPKRGGE--------FMHSASPMIMDMMAEKGNFIYTDNRSYAQKDIYGD 954

  Fly   682 PNPVSTDPAKSYRDIVHSH 700
            .:.:.:.....::|.::::
Zfish   955 SSDLQSYLTNRHKDHLNNY 973

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir64a	NP_647962.1	Periplasmic_Binding_Protein_Type_2	351..>465	CDD:304360	23/148 (16%)
		Lig_chan	563..828	CDD:278489	34/172 (20%)
grin2aa	XP_021329529.1	PBP1_iGluR_NMDA_NR2	33..389	CDD:107373	34/166 (20%)
		PBP2_iGluR_NMDA_Nr2	400..799	CDD:270436	60/425 (14%)
		NMDAR2_C	836..1460	CDD:313729	28/146 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591439
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.830