Protein Alignment Ir64a and grik4

DIOPT Version :10

• Sequence 1: NP_647962.1
• Gene: Ir64a / 38616
• FlyBaseID: FBgn0035604
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: XP_021322088.1
• Gene: grik4 / 556582
• ZFINID: ZDB-GENE-070821-5
• Length: 965
• Species: Danio rerio
• Alignment Length: 648
• Identity: 115/648 - (17%)
• Similarity: 204/648 - (31%)
• Gaps: 217/648 - (33%)

  Fly   264 VWNPG---LNY---------GGHV---------------------NLTEIGSFTPTEGIQLH--- 292
            :|..|   :||         .||:                     .|.:||.:...:|:.:.
Zfish   340 IWEHGTSLMNYLRMVELEGLTGHIEFNSKGQRSNYALRIMQNSRDGLRQIGQWHSEQGLSMERKL 404

  Fly   293 -------TWFRTTSTVRRRMDMQHARVRCMVVVTNKNMTGTLMYYLTHTMSGHIDTMNRFNFNLL 350
                   |.|.||.|:...::..:..:|    ..::.:.|.             |....|..::|
Zfish   405 PSLNVTDTLFNTTLTITTILENPYVMLR----ANHQELEGN-------------DRYEGFCVDML 452

  Fly   351 MAVRDMFNWTFVLSRTTSWGY---VKNGRFDGMIGALIRNETDIGGAPIFYWLERHKWIDVAGRS 412
            ..:.|:..:.:.:.......|   ..||.:.||:|.||..:.|:..|.:....||.|.||.:...
Zfish   453 KELADILKFKYRIRLVGDGVYGVPGANGTWTGMVGELISRKADLAVAALTITAEREKVIDFSKPF 517

  Fly   413 WSSRPCFIFRHPRSTQKDRIVFLQPFTNDVWI------LIVGCGVLTVFILWFLTTIEWKLVPHD 471
            .:.....::|.....:.....||.||:..||:      |.|.|   .:|::..||..|| ..||
Zfish   518 MTLGISIMYRVHIGRRPGYFSFLDPFSPGVWLFMLLAYLAVSC---VLFLVARLTPYEW-YNPH- 577

  Fly   472 GSALIKPKGGAPPRHHYQQQQQQEQVEAPVRPITAVSVVVSKEKVEEKQEEYEDSTPIDAGTLWQ 536
                                                                    |...|
Zfish   578 --------------------------------------------------------PCLKG---- 582

  Fly   537 RCYQKLNKYIKDRKAKQKKAPERVGLFLESVLFFVGIICQQGLGFSTSFVSGRCIVITSLLFSFC 601
            ||...:|:|             .:|   .|..|.||...|||...:...:|.||:......|:..
Zfish   583 RCSLLINQY-------------SLG---NSFWFPVGGFMQQGSTIAPRALSTRCVSGVWWAFTLI 631

  Fly   602 IYQFYSASIVGTLLMEKPKT-IKTLSDLVHSSLKVGMEDILYNRDYFLHTKDPVSMELYAKKITS 665
            |...|:|::...|.:::.:. |:::.||.                      |..::|.......|
Zfish   632 IISSYTANLAAFLTVQRMEVPIESVDDLA----------------------DQTAIEYGTMHGGS 674

  Fly   666 VPTTKENEADEDEPVDPNPVSTDPAKSYR---DIVHSHETGAHAKDNAASNWLDPETGLLRHLGF 727
            ..|..:|..               .::|:   :.::|.:.....|..        |.|:.|.|..
Zfish   675 TMTFFQNSR---------------YQTYQRMWNFMYSKQPSVFVKST--------EEGIARVLNS 716

  Fly   728 AFHVDVAAAYKIIAETFSE---QDICDLTEVSMFPPQKTVSI-MQKNSPMRKVISYGLRRVTETG 788
            .:      || ::..|.:|   |..|:||::......|...| |...|..|......:.|:.|..
Zfish   717 NY------AY-LLESTMNEYYRQRNCNLTQIGGLLDTKGYGIGMPLGSVYRDEFDLAILRLQEEN 774

  Fly   789 ---ILTYHFNVWHSRKPPCVKKIETSDLHVDMDTVSSALLILLFSYAITLMILGTEILYSKWH 848
               ||...:  |...|  |.|:.:.....:.|:.:....::|:....:.:.:...|.::...|
Zfish   775 RLEILKRKW--WDGGK--CPKEEDHRAKGLGMENIGGIFVVLVCGLLVAIFMAVLEFVWMLRH 833

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir64a	NP_647962.1	Periplasmic_Binding_Protein_Type_2	351..>465	CDD:473866	29/122 (24%)
		Lig_chan	563..828	CDD:459656	52/275 (19%)
grik4	XP_021322088.1	Periplasmic_Binding_Protein_type1	24..401	CDD:471960	10/60 (17%)
		PBP2_iGluR_kainate_KA1	425..785	CDD:270442	92/511 (18%)