Protein Alignment Ir64a and Gria1

DIOPT Version :9

• Sequence 1: NP_647962.1
• Gene: Ir64a / 38616
• FlyBaseID: FBgn0035604
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: NP_113796.1
• Gene: Gria1 / 50592
• RGDID: 621531
• Length: 907
• Species: Rattus norvegicus
• Alignment Length: 502
• Identity: 95/502 - (18%)
• Similarity: 167/502 - (33%)
• Gaps: 165/502 - (32%)

  Fly   366 TTSWGYVKNGRFDGMIGALIRNETDIGGAPIFYWLERHKWIDVAGRSWSSRPCFIFRHPRSTQKD 430
            |.:|        :||:|.|:....|:..||:...|.|.:.||.:....|.....:.:.|:.::..
  Rat   471 TKAW--------NGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPG 527

  Fly   431 RIVFLQPFTNDVWILIV----GCGVLTVFILWFLTTIEWKLVPHDGSALIKPKGGAPPRHHYQQQ 491
            ...||.|...::|:.||    |..|: :|::...:..||.
  Rat   528 VFSFLDPLAYEIWMCIVFAYIGVSVV-LFLVSRFSPYEWH------------------------- 566

  Fly   492 QQQEQVEAPVRPITAVSVVVSKEKVEEKQEEYEDSTPIDAGTLWQRCYQKLNKYIKDRKAKQKKA 556
                                     .|:.||..|.|..|          :.|::
  Rat   567 -------------------------SEEFEEGRDQTTSD----------QSNEF----------- 585

  Fly   557 PERVGLFLESVLFFVGIICQQGLGFSTSFVSGRCIVITSLLFSFCIYQFYSASIVGTLLMEK-PK 620
                |:| .|:.|.:|...|||...|...:|||.:......|:..|...|:|::...|.:|: ..
  Rat   586 ----GIF-NSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVS 645

  Fly   621 TIKTLSDL------VHSSLKVGMEDILYNRDYFLHTKDPV--SMELYAKKITSVPTTKENEADED 677
            .|::..||      .:.:|:.|.     .:::|..:|..|  .|..|.|
  Rat   646 PIESAEDLAKQTEIAYGTLEAGS-----TKEFFRRSKIAVFEKMWTYMK---------------- 689

  Fly   678 EPVDPNPVSTDPAKSYRDIVHSHETGAHAKDNAASNWLDPETGLLR---HLG-FAFHVDVAAAYK 738
                    |.:|:...|                     ..|.|::|   ..| :|:.::     .
  Rat   690 --------SAEPSVFVR---------------------TTEEGMIRVRKSKGKYAYLLE-----S 720

  Fly   739 IIAETFSEQDICDLTEVSMFPPQKTVSI-MQKNSPMRKVISYGLRRVTETGILTYHFNVWHSRKP 802
            .:.|...::..||..:|......|...| ..|.|.:|..::..:.::.|.|:|....|.|...|.
  Rat   721 TMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRNPVNLAVLKLNEQGLLDKLKNKWWYDKG 785

  Fly   803 PC-----VKKIETSDLHVDMDTVSSALLILLFSYAITLMILGTEILY 844
            .|     ..|.:||.|  .:..|:....||:....:.:::...|..|
  Rat   786 ECGSGGGDSKDKTSAL--SLSNVAGVFYILIGGLGLAMLVALIEFCY 830

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir64a	NP_647962.1	Periplasmic_Binding_Protein_Type_2	351..>465	CDD:304360	24/102 (24%)
		Lig_chan	563..828	CDD:278489	58/283 (20%)
Gria1	NP_113796.1	PBP1_iGluR_AMPA_GluR1	26..392	CDD:380613
		PBP2_iGluR_AMPA_GluR1	406..787	CDD:270447	85/455 (19%)
		Glutamate binding. /evidence=ECO:0000250	492..494		1/1 (100%)
		Glutamate binding. /evidence=ECO:0000250	668..669		0/5 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	857..881
		PDZ-binding	904..907

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349967
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940