Protein Alignment Ir64a and Ekar

DIOPT Version :9

• Sequence 1: NP_647962.1
• Gene: Ir64a / 38616
• FlyBaseID: FBgn0035604
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: NP_001036250.1
• Gene: Ekar / 43806
• FlyBaseID: FBgn0039916
• Length: 899
• Species: Drosophila melanogaster
• Alignment Length: 658
• Identity: 116/658 - (17%)
• Similarity: 203/658 - (30%)
• Gaps: 202/658 - (30%)

  Fly   221 IQATDDEDLPSIESFLGGMNLYMNTELTLAKRMSEAAHYTLFDV--WNPGLNYGGHVNLTEIGSF 283
            :.|.:.:.|.....|..|..:....:|...|:      :::..|  |.|    .||:|:||...|
  Fly   341 LNAVEWKGLTGPIQFKDGQRVQFKLDLIKLKQ------HSIVKVGEWTP----HGHLNITEPSMF 395

  Fly   284 TPTEGIQLHTWFRTTSTVRRRMDMQHARVRCMVVVT-----------NKNMTGTLMYYLTHTMSG 337
            .....:.:                      .:||:|           .||.||...:|
  Fly   396 FDAGSMNV----------------------TLVVITILETPYVMMHYGKNFTGNERFY------- 431

  Fly   338 HIDTMNRFNFNLLMAVRDMFNWTFVLSRTTSWGY----VKNGRFDGMIGALIRNETD--IGGAPI 396
                  .|..::|..:.....:.::|.......|    .:.|.::||:..|::.:.|  :|...|
  Fly   432 ------GFCVDILETISREVGFDYILDLVPDRKYGAKDPETGEWNGMVAQLMKYKADLAVGSMTI 490

  Fly   397 FYWLERHKWIDVAGRSWSSRPCFIFRHPRSTQKDRIVFLQPFTNDVWILIVGCGVLT---VFILW 458
            .|  .|...||......:.....:|:.|.|.......|:.|...::||.::....|.   ::|:.
  Fly   491 TY--ARESVIDFTKPFMNLGISILFKVPTSEPTRLFSFMNPLAIEIWIYVLIAYFLVSLCIYIVG 553

  Fly   459 FLTTIEWKLVPHDGSALIKPKGGAPPRHHYQQQQQQEQVEAPVRPITAVSVVVSKEKVEEKQEEY 523
            .|:.||||.                                    |.|.
  Fly   554 KLSPIEWKC------------------------------------INAC---------------- 566

  Fly   524 EDSTPIDAGTLWQRCYQKLNKYIKDRKAKQKKAPERVGLFLESVLFFVGIICQQGLGFSTSFVSG 588
             |...|..|..:.                          ..:|..|.:|...||........:|.
  Fly   567 -DLENISIGNQFS--------------------------LTDSFWFTIGTFMQQSPDIYPRAMST 604

  Fly   589 RCIVITSLLFSFCIYQFYSASIVGTLLMEKP-KTIKTLSDLV-HSSLKVGMEDILYNRDYFLHTK 651
            |.|..|...||..|...|:|::...|..|:. ..|:...||. .:.:..|..|......:|   :
  Fly   605 RIISSTWGFFSLIIVASYTANLAAFLTTERMINPIENAEDLASQTEISYGTLDSGSTMTFF---R 666

  Fly   652 DPVSMELYAKKITSVPTTKENEADEDEPVDPNPVSTDPAKSYRDIVHSHETGAHAKDNAASNWLD 716
            |.| :|.|.|...|:...|           |:..:|    :|.|.:.....|
  Fly   667 DSV-IETYKKIWRSMDNKK-----------PSAFTT----TYEDGIKRVNQG------------- 702

  Fly   717 PETGLLRHLGFAFHVDVAAAYKIIAETFSEQDICDLTEVSMFPPQKTVSI-MQKNSPMRKVISYG 780
                     .:||.::......|:      |..|:||::......|...| ..|.||.|..||..
  Fly   703 ---------NYAFLMESTMLDYIV------QRDCNLTQIGGLLDTKGYGIATPKGSPWRDKISLA 752

  Fly   781 LRRVTETG-ILTYHFNVWHSRKPPCVKKIETSDLHVD---MDTVSSALLILLFSYAITLMILGTE 841
            :..:.|.| |...:...|.:....|.:|..:.....:   ::::....::|:....:..::...|
  Fly   753 ILELQERGDIQMLYDKWWKNTDETCTRKNTSKQSKANSLGLESIGGVFVVLIAGIIVAAVVAFFE 817

  Fly   842 ILYSKWHN 849
            ..|:..:|
  Fly   818 FWYNFRYN 825

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir64a	NP_647962.1	Periplasmic_Binding_Protein_Type_2	351..>465	CDD:304360	24/122 (20%)
		Lig_chan	563..828	CDD:278489	55/271 (20%)
Ekar	NP_001036250.1	PBP1_iGluR_Kainate	24..388	CDD:107377	11/56 (20%)
		ANF_receptor	39..371	CDD:279440	5/29 (17%)
		PBP2_iGluR_Kainate	402..771	CDD:270432	94/531 (18%)
		Lig_chan	533..807	CDD:278489	70/399 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462975
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840