Protein Alignment Ir64a and GluRIIB

DIOPT Version :9

• Sequence 1: NP_647962.1
• Gene: Ir64a / 38616
• FlyBaseID: FBgn0035604
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: NP_523485.3
• Gene: GluRIIB / 33789
• FlyBaseID: FBgn0020429
• Length: 913
• Species: Drosophila melanogaster
• Alignment Length: 834
• Identity: 156/834 - (18%)
• Similarity: 257/834 - (30%)
• Gaps: 323/834 - (38%)

  Fly    75 NAAEHRDAFAAKNFQLIKSLYESELFVRIVLLDVLAQSPTSGRPNRPGNGPTGGFSQTPSQAQSN 139
            |:.:.|  |::...||:   |:|.:.....||::      |.||         || ..|:.:...
  Fly   286 NSVDTR--FSSLGSQLV---YDSIVLFYNALLEI------SQRP---------GF-YIPNFSCGR 329

  Fly   140 SEWLEGVLRMEALRQIAVVDLACGAVSRRFLELASAKMLYSEKFHWLLIEDFAWHGRTQTAE--G 202
            ..|..|...:|.::||                  :.||: ...|            :||..:  .
  Fly   330 GFWQPGPRLVEQMKQI------------------TPKMV-KPPF------------KTQRLQINA 363

  Fly   203 SGKRDDGEMEEEEPP--------GQQIQATDDEDLPSIESFLGGMNLYMNTELTLAKRM------ 253
            .|:|:|..:|...|.        .::.|..|.|.|..           .:|:....||:
  Fly   364 DGQREDFNLEVYNPIIDRVTHIWNKEFQLVDFEKLRE-----------NSTQALKQKRLQNKEDF 417

  Fly   254 -SEAAHYTL-------FDVWN---PGLNYGGHVNLTEIGSFTPTEGIQLHTWFRTTSTVRRRMDM 307
             .:...||:       :..|.   .|::|.|:...         ||..:
  Fly   418 SQKPIRYTVATRVGKPYFSWREEPEGVHYEGNERF---------EGYAV---------------- 457

  Fly   308 QHARVRCMVVVTNKNMTGTLMYYLTHTMSGHIDTMNRFNFNLLMAVRDMFNWTFVLSRTTSWGYV 372
                              .|:|.|....        :|:|| ...|||....::. :.|..|
  Fly   458 ------------------DLIYMLAQEC--------KFDFN-FEPVRDNKYGSYD-ANTDEW--- 491

  Fly   373 KNGRFDGMIGALIRNETDIGGAPIFYWLERHKWID---------VAGRSWSSRPCFIFRHPRSTQ 428
                 ||:|..||.|...||...:.....|...:|         ::..|:...|      |::
  Fly   492 -----DGIIRQLIDNNAQIGICDLTITQARRSVVDFTVPFMQLGISILSYKEPP------PKA-- 543

  Fly   429 KDRIVFLQPFTNDVWILIVGCGVLTVFILWFLTTIEWKLVPHDGSALIKPKGGAPPRHHYQQQQQ 493
             |...||.|:..:||:.::...::|.|.|.|...|:                      .|:..|.
  Fly   544 -DIYAFLNPYNAEVWLFVMIAMMITAFALIFTGRID----------------------QYEWDQP 585

  Fly   494 QEQVEAPVRPITAVSVVVSKEKVEEKQEEYEDSTPIDAGTLWQRCYQKLNKYIKDRKAKQKKAPE 558
            .|.|...:                |:|            .:|.
  Fly   586 VENVNREM----------------ERQ------------NIWH---------------------- 600

  Fly   559 RVGLFLESVLFFV-GIICQQGLGFSTSFVSGRCIVITSLLFSFCIYQFYSASIVGTLLMEK-PKT 621
                 |.:.|:.| |.:..||.......:..|.:.....:|:..|.|.|.|.:...:...| ...
  Fly   601 -----LSNALWLVLGSMLNQGCDLLPRGLPMRLLTAFWWIFALLISQTYIAKLAAFITSSKIAGD 660

  Fly   622 IKTLSDLV------HSSLKVGMEDILYNRDYFLHTKDPVSMELYAKKITSVPT--TKENEADEDE 678
            |.:|.|||      ..:::.|...:     ||..:.|..:...:.|.::..|.  ||.||    |
  Fly   661 IGSLHDLVDQNKVQFGTIRGGATSV-----YFSESNDTDNRMAWNKMLSFKPDAFTKNNE----E 716

  Fly   679 PVDPNPVSTDPAKSYRDIVHSHETGAHAKDNAASNWLDPETGLLRHLGFAFHVDVAAAYKIIAET 743
            .||...:|                                               ...|..:.||
  Fly   717 GVDRVKLS-----------------------------------------------KGTYAFLMET 734

  Fly   744 ----FSEQDICDLTEVSMFPPQKTVSI-MQKNSPMRKVISYGLRRVTETGILTYHFNVW-HSRKP 802
                :..|..|:||::.....:|...| :..|:..|..:|.|:.|::|.|.|....|.| :|.:.
  Fly   735 TNLQYYVQRNCELTQIGESFGEKHYGIAVPLNADFRSNLSVGILRLSERGELFKLRNKWFNSNES 799

  Fly   803 PCVKKIET-SDLHVDMDTVSSALLILLFSYAITLMILGTEILYSKWH-NRIQLK 854
            .|...:.| .|...|||:|....::|:....:.|:|...|.|   || .||.:|
  Fly   800 TCDSNVPTIDDGQFDMDSVGGLFVVLIVGVVVGLVIGVAEFL---WHVQRISVK 850

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir64a	NP_647962.1	Periplasmic_Binding_Protein_Type_2	351..>465	CDD:304360	29/122 (24%)
		Lig_chan	563..828	CDD:278489	59/281 (21%)
GluRIIB	NP_523485.3	PBP1_iGluR_Kainate	26..393	CDD:107377	31/158 (20%)
		ANF_receptor	41..378	CDD:279440	29/143 (20%)
		PBP2_iGluR_Kainate	422..795	CDD:270432	101/575 (18%)
		Lig_chan	555..822	CDD:278489	73/399 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462614
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840