Protein Alignment Ir64a and GluRIIC

DIOPT Version :10

• Sequence 1: NP_647962.1
• Gene: Ir64a / 38616
• FlyBaseID: FBgn0035604
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: NP_608557.4
• Gene: GluRIIC / 33275
• FlyBaseID: FBgn0046113
• Length: 940
• Species: Drosophila melanogaster
• Alignment Length: 608
• Identity: 112/608 - (18%)
• Similarity: 188/608 - (30%)
• Gaps: 205/608 - (33%)

  Fly   283 FTPTEGIQLHTWFRTTSTVRRRMDMQHARVRCMVVVT--------------NKNMTGTLMYY--- 330
            :.|.:||.:..|.......:..:|::..:.....|.|              ..|:||..:|.
  Fly   391 YDPLDGIGIAIWDPRGQITQLNVDVKAQKKMIYRVATRIGPPYFSYNETARELNLTGNALYQGYA 455

  Fly   331 --LTHTMSGHIDTMNRFNFNLLMAVRDMFNWTFVLSRTTSWGYV--KNGRFDGMIGALIRNETDI 391
              |...::.|:.                |.:.||......:|.:  :..:::|:||.:|.|:..:
  Fly   456 VDLIDAIARHVG----------------FEYVFVPVADQQYGKLDKETKQWNGIIGEIINNDAHM 504

  Fly   392 GGAPIFYWLERHKWIDVA------GRSWSSRPCFIFRHPRSTQKDRIVFLQPFTNDVWILIVGCG 450
            |...:.....|...:|..      |.|     ...::.|. .:|....:|.||..:|||.|
  Fly   505 GICDLTITQARKTAVDFTVPFMQLGVS-----ILAYKSPH-VEKTLDAYLAPFGGEVWIWI---- 559

  Fly   451 VLTVFILWFLTTI-------EWKLVPHDGSALIKPKGGAPPRHHYQQQQQQEQVEAPVRPITAVS 508
            :::||::.||.||       :|: .||       |....|
  Fly   560 LISVFVMTFLKTIVARISKMDWE-NPH-------PCNRDP------------------------- 591

  Fly   509 VVVSKEKVEEKQEEYEDSTPIDAGTLWQRCYQKLNKYIKDRKAKQKKAPERVGLFLESVLFFVGI 573
                  :|.|.|....:       |.|                                 ..|..
  Fly   592 ------EVLENQWRIHN-------TGW---------------------------------LTVAS 610

  Fly   574 ICQQGLGFSTSFVSGRCIVITSLLFSFCIYQFYSASIVGTLLMEKPK-TIKTLSDLVHSSLKVGM 637
            |...|..........|....|..:|:..|...|:|::...|...|.: :|..|.|| .:..||..
  Fly   611 IMTAGCDILPRSPQVRMFEATWWIFAIIIANSYTANLAAFLTSSKMEGSIANLKDL-SAQKKVKF 674

  Fly   638 EDILYNRDYFLHTKDPVSMELYAKKITSVPTTKENEADEDEPVDPNPVSTDPAKSYR---DIVHS 699
            ..|.....|.|                        .||.:|.|            ||   :::::
  Fly   675 GTIYGGSTYNL------------------------LADSNETV------------YRLAFNLMNN 703

  Fly   700 HETGAHAKDNAASNWLDPETGLLRHLGFAFHVDVAAAYKIIAET----FSEQDICDLTEVSMFPP 760
            .:..|:.|||     |:....:.::.|         .|..:.||    :..:..|||..|.....
  Fly   704 DDPSAYTKDN-----LEGVDRVRKNRG---------DYMFLMETTTLEYHREQNCDLRSVGEKFG 754

  Fly   761 QKTVSI-MQKNSPMRKVISYGLRRVTETGILTYHFNVWHSRKPPCVKKIETSDLHVDMDTVSSAL 824
            :|..:| :...:..|..:|..:.:::|.|.|......|.  |.|.....|..|.....|.....|
  Fly   755 EKHYAIAVPFGAEYRSNLSVAILKLSERGELYDLKQKWW--KNPNASCFEEPDPDATPDMTFEEL 817

  Fly   825 LILLFS-YA---ITLMILGTEIL 843
            ..:.:: ||   |..:|..||.|
  Fly   818 RGIFYTLYAGILIAFLIGITEFL 840

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir64a	NP_647962.1	Periplasmic_Binding_Protein_Type_2	351..>465	CDD:473866	29/128 (23%)
		Lig_chan	563..828	CDD:459656	53/273 (19%)
GluRIIC	NP_608557.4	Periplasmic_Binding_Protein_type1	26..409	CDD:471960	4/17 (24%)
		PBP2_iGluR_Kainate	423..794	CDD:270432	94/528 (18%)
		Lig_chan	554..827	CDD:459656	74/408 (18%)