Protein Alignment Ir64a and Ir31a

DIOPT Version :10

• Sequence 1: NP_647962.1
• Gene: Ir64a / 38616
• FlyBaseID: FBgn0035604
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: XP_061519115.1
• Gene: Ir31a / 3291880
• VectorBaseID: AGAMI1_005634
• Length: 763
• Species: Anopheles gambiae
• Alignment Length: 805
• Identity: 145/805 - (18%)
• Similarity: 280/805 - (34%)
• Gaps: 278/805 - (34%)

  Fly   241 LYMNTELTLAKRMSEAAH---YTLFDVWNPGLNYGGHVNLTEIGSFTPTEGIQLHTWFRTT---S 299
            :.||::|..|...::  |   :.|||:::.|.:....:..|.:|:::...|      ||.|   |
Mosquito    29 IQMNSDLVAAIETTD--HRGVFNLFDIYSKGRHLCKDIFQTLLGTWSADVG------FRLTPNYS 85

  Fly   300 TVRRRMDMQHARVRCMVVVTNKNMTGTLMYYLTHTMSGHIDTM-------------NRFNFNLLM 351
            ..:.|.:....::|.:.|:..:|:|           ||.:|.:             .::::.||:
Mosquito    86 PYKIRQNFNFLQLRGVTVIDRENVT-----------SGKVDQLLGEPGLTKGIVAFVKYHYALLV 139

  Fly   352 AVRDMFNWTFVLSRTTSW-GYVKNGRFDGMIGALIRNETDIGGAPIFYWLERHKWIDVAGRSWSS 415
            .:||..|:|.....|..| |.:::|...|::|.:.|:|||:....|...|.|...:|....||:.
Mosquito   140 VLRDFHNFTIKFRPTRGWAGRLRSGYRLGLLGVVQRHETDVAATGIIMRLSRQPELDSIHYSWAF 204

  Fly   416 RPCFIFR--HPRSTQKDRIVFLQPFTNDVWILIVGCGVLTVFILWFLTTIE-------------- 464
            ...||::  ....::.:...|:.||:..||:.::....|:|.:|.:|..:.
Mosquito   205 ETGFIYKITPDIGSKSEGNGFVAPFSLPVWVALLLSLALSVLVLQYLARLSADERNTRATMAYVL 269

  Fly   465 --------------WKLVPHDGSALIKPKGGAPPRHHYQQQQQQEQVEAPVRPITAVSVVVSKEK 515
                          .:|||...:.::.........::|..              |.||.::|.:.
Mosquito   270 DVMACVAQQGVPNVSRLVPTRVAVIVLLVANLVLYNYYTS--------------TVVSGLLSSQM 320

  Fly   516 VEEKQEEYEDSTPI-----DAGTLWQRCYQKL---------NKYIKDRKAKQKKAPERVGLF--- 563
            :..:.......:|:     |.|      |.::         :..:.:|||...::|..:.||
Mosquito   321 IGPETIAQVIDSPLLLSLTDTG------YHRILLREQTLPYSTRMHERKALPPRSPNDLPLFTDV 379

  Fly   564 ----------------------------------------------------------------- 563
                                                                             
Mosquito   380 EHAVPYLRRGGHVLHCELTEVYPAIANQFTANEICELRTVEGLYRYDIRVMAFVLPKHSMYSELF 444

  Fly   564 ---------------------------------------------LESVLFF------------- 570
                                                         |:.:..|
Mosquito   445 KITLGFIFRLTPELNGATRETSYLSPFTDTTWYSVASVLALVLGVLQCIAIFHAELSSLARNHYL 509

  Fly   571 ---VGIICQQGLGFSTSFVSGRCIVITSLLFSFCIYQFYSASIVGTLLMEKPKTIKTLSDLVHSS 632
               :|:|.|||...|::::|.|.::...|:.:|.:|.:|:|||||.||....:...|:..|:::.
Mosquito   510 IDTIGLIAQQGTAQSSAYISLRIVLYAVLIMAFLLYNYYTASIVGELLSCSNQGPATIDQLLNAP 574

  Fly   633 LKVGMEDILYNRDYFLHTKDPVSME---LYAKKITSVPTTKENEADEDEPVDPNPVSTDPAKSYR 694
            |.|...:..|||...:.......|:   ||.::...||....::                 :.|.
Mosquito   575 LAVMFANDSYNRALAVDNGTGGLMQHYILYEQQHARVPDAMTSD-----------------RIYA 622

  Fly   695 DIVHSHETGAHAKDNAASNWLDPETGLLRHLGFAFHVDVAAAYKIIAETFSEQDICDL-TEVSMF 758
            |:    .|...               ||:..|:|||.::..|::.||..|...:||:| |...::
Mosquito   623 DV----RTAVQ---------------LLKLGGYAFHCELTEAFRAIASHFDAHEICELRTMKGLY 668

  Fly   759 PPQKTVS-IMQKNSPMRKVISYGLRRVTETGILTYHFNVWHSRKPPCVKKIETSDLH-VDMDTVS 821
            .....:| ::.:.|...:.....|.|.||.|::......:.|.:|.|   :....:| |.:..|:
Mosquito   669 TELPLMSFVVPQGSMYAEQFKITLTRATEIGLIKRLLKTYSSDQPTC---LGGPLVHPVVLAGVT 730

  Fly   822 SALLILLFSYAITLMI-LGTEILYS 845
            :...||...:..:.:| |..:|:||
Mosquito   731 APFTILAAGFVSSFVIFLLEKIIYS 755

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir64a	NP_647962.1	Periplasmic_Binding_Protein_Type_2	351..>465	CDD:473866	31/144 (22%)
		Lig_chan	563..828	CDD:459656	65/399 (16%)
Ir31a	XP_061519115.1	None