Protein Alignment Ir64a and GRIN2C

DIOPT Version :9

• Sequence 1: NP_647962.1
• Gene: Ir64a / 38616
• FlyBaseID: FBgn0035604
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: XP_016880033.1
• Gene: GRIN2C / 2905
• HGNCID: 4587
• Length: 1337
• Species: Homo sapiens
• Alignment Length: 671
• Identity: 114/671 - (16%)
• Similarity: 227/671 - (33%)
• Gaps: 193/671 - (28%)

  Fly   234 SFLGGMNLYMNTELTLAKRMSEAAHYTLFDVWNPGLNYGGHVNLTEIGSFTPTEGIQLHTWFRTT 298
            ||..|..|...|.:.:|  ::....:.:...|..|:.|                 ::...|.|.:
Human   421 SFSPGGYLVQPTMVVIA--LNRHRLWEMVGRWEHGVLY-----------------MKYPVWPRYS 466

  Fly   299 STVRRRMDMQHARV-----RCMVVVTNKNMTGT---------LMYYLTHTM-SGHIDTMNR---- 344
            ::::..:|.:|..|     |..|:|.:.: .||         ......||. ||.:....:
Human   467 ASLQPVVDSRHLTVATLEERPFVIVESPD-PGTGGCVPNTVPCRRQSNHTFSSGDVAPYTKLCCK 530

  Fly   345 -FNFNLLMAVRDMFNWTFVLSRTTSWGYVK--NGRFDGMIGALIRNETDIGGAPIFYWLERHKWI 406
             |..::|..:..:..:::.|...|:..:.|  .|.::||||.:.....|:....:....||.:.:
Human   531 GFCIDILKKLARVVKFSYDLYLVTNGKHGKRVRGVWNGMIGEVYYKRADMAIGSLTINEERSEIV 595

  Fly   407 D-------------VAGRSWSSRPCFIFRHPRSTQKDRIVFLQPFTNDVWILI-VGC---GVLTV 454
            |             ||..:.:..|.              .||:|::..||::: |.|   ..:||
Human   596 DFSVPFVETGISVMVARSNGTVSPS--------------AFLEPYSPAVWVMMFVMCLTVVAITV 646

  Fly   455 FILWFLTTIEWKLVPHDGSALIKPKGGAPPRHHYQQQQQQEQVEAPVRPITAVSVVVSKEKVEEK 519
            |:..:.:.:.:......|.     |.|.|                        :..:.|
Human   647 FMFEYFSPVSYNQNLTRGK-----KSGGP------------------------AFTIGK------ 676

  Fly   520 QEEYEDSTPIDAGTLWQRCYQKLNKYIKDRKAKQKKAPERVGLFLESVLFFVGIICQQGLGFSTS 584
                         ::|                           .|.:::|...:..:...|
Human   677 -------------SVW---------------------------LLWALVFNNSVPIENPRG---- 697

  Fly   585 FVSGRCIVITSLLFSFCIYQFYSASIVGTLLMEK-PKTIKTLSDLVHSSLKVGMEDILYN----- 643
             .:.:.:|:....|:......|:|::...::.|: ..|:..|||  ..||.:....:.:.
Human   698 -TTSKIMVLVWAFFAVIFLASYTANLAAFMIQEQYIDTVSGLSD--KKSLHLENTGVAWTAFKTF 759

  Fly   644 -RDYFLHTKDPVSMELYAKKITSVP--TTKENEADEDEPVDPNPVSTDPAKSYRDIVHSHETGAH 705
             .|||...:|    :....:..:||  :|:.|.......:..:.|..: .:|..|.:.|.:.|:.
Human   760 CSDYFQRPQD----QYPPFRFGTVPNGSTERNIRSNYRDMHTHMVKFN-QRSVEDALTSLKMGSE 819

  Fly   706 AKDNAASNWLDPETGLLRHLGFAFHVDVAAAYKIIAETFSEQDICDLTEV---SMFPPQKTVSIM 767
            |:  .....||           ||..|.|    ::.....:.:.|.|..:   .:|........|
Human   820 AQ--PVPRKLD-----------AFIYDAA----VLNYMAGKDEGCKLVTIGSGKVFATTGYGIAM 867

  Fly   768 QKNSPMRKVISYGLRRVTETGILTYHFNVWHSRKPPCV-KKIETSDLHVDMDTVSSALLILLFSY 831
            ||:|..::.|...|.:....|.......||.|  ..|. :|.|.....:|:|.::....:||.:.
Human   868 QKDSHWKRAIDLALLQFLGDGETQKLETVWLS--GICQNEKNEVMSSKLDIDNMAGVFYMLLVAM 930

  Fly   832 AITLMILGTE-ILYSKWHNRI 851
            .:.|::...| ::|.|..:.:
Human   931 GLALLVFAWEHLVYWKLRHSV 951

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir64a	NP_647962.1	Periplasmic_Binding_Protein_Type_2	351..>465	CDD:304360	25/132 (19%)
		Lig_chan	563..828	CDD:278489	52/277 (19%)
GRIN2C	XP_016880033.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156117
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740