DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir64a and Grin2d

DIOPT Version :9

Sequence 1:	NP_647962.1	Gene:	Ir64a / 38616	FlyBaseID:	FBgn0035604	Length:	859	Species:	Drosophila melanogaster
Sequence 2:	XP_038951440.1	Gene:	Grin2d / 24412	RGDID:	2740	Length:	1334	Species:	Rattus norvegicus

Alignment Length:	290	Identity:	57/290 - (19%)
Similarity:	104/290 - (35%)	Gaps:	85/290 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   266 NPGLNYGGHVNLTE------IGSF-TPTEGIQLHTWFRTTSTVRRRMDMQHARV-----RCMVVV 318
            ||.|..   ::||.      :||: ..|..::...|.|....::...|.||..|     |..|:|
  Rat   381 NPSLVV---ISLTRDRTWEVVGSWEQQTLRLKYPLWSRYGRFLQPVDDTQHLTVATLEERPFVIV 442

  Fly   319 TNKN-MTGTLM-------YYLTHTMSGHIDT-------MNRFNFNLLMAVRDMFNWTFVLSRTTS 368
            ...: ::||.:       ..|..|.|...|.       ...|..::|..:.....:::.|...|:
  Rat   443 EPADPISGTCIRDSVPCRSQLNRTHSPPPDAPRPEKRCCKGFCIDILKRLAHTIGFSYDLYLVTN 507

  Fly   369 WGYVK--NGRFDGMIGALIRNETDIGGAPIFYWLERHKWID-------------VAGRSWSSRP- 417
            ..:.|  :|.::||||.:.....|:....:....||.:.:|             ||..:.:..|
  Rat   508 GKHGKKIDGVWNGMIGEVFYQRADMAIGSLTINEERSEIVDFSVPFVETGISVMVARSNGTVSPS 572

  Fly   418 ---CFIFRHPRSTQKDRIVFLQPFTNDVWILI-VGC---GVLTVFILWFLTTIE----------- 464
               .|.:..|..:.       :|::..||::: |.|   ..:||||..:|:.:.
  Rat   573 AFLAFAWLTPPMSP-------EPYSPAVWVMMFVMCLTVVAVTVFIFEYLSPVGYNRSLATGKRP 630

  Fly   465 --------------WKLVPHDGSALIKPKG 480
                          |.||.::...:..|:|
  Rat   631 GGSTFTIGKSIWLLWALVFNNSVPVENPRG 660

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir64a	NP_647962.1	Periplasmic_Binding_Protein_Type_2	351..>465	CDD:304360	27/161 (17%)
Ir64a	NP_647962.1	Lig_chan	563..828	CDD:278489
Grin2d	XP_038951440.1	PBP1_iGluR_NMDA_NR2	46..410	CDD:380601	8/31 (26%)
		PBP2_iGluR_NMDA_Nr2	427..838	CDD:270436	46/241 (19%)
		PHA03307	<1125..>1312	CDD:223039
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350043
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830