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Protein Alignment Ir64a and Grin2a

DIOPT Version :9

Sequence 1:	NP_647962.1	Gene:	Ir64a / 38616	FlyBaseID:	FBgn0035604	Length:	859	Species:	Drosophila melanogaster
Sequence 2:	NP_036705.3	Gene:	Grin2a / 24409	RGDID:	2737	Length:	1464	Species:	Rattus norvegicus

Alignment Length:	794	Identity:	132/794 - (16%)
Similarity:	236/794 - (29%)	Gaps:	298/794 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   173 ASAKMLYSEKFHWLLI-----------EDFAW------HGRTQTAEGSGKRDDGEMEEEEPPGQQ 220
            :|..:||..|...:||           .||.|      .|.|:.           :.:|.|.|..
  Rat   224 SSVILLYCSKDEAVLILSEARSLGLTGYDFFWIVPSLVSGNTEL-----------IPKEFPSGLI 277

  Fly   221 IQATDDEDLPSIESFL-GGMNLYMNTELTLAKRMS----------------EAAHYTLFDVWNPG 268
            ..:.||.|. |:|:.: .|:.:......::.::.|                |...:||....
  Rat   278 SVSYDDWDY-SLEARVRDGLGILTTAASSMLEKFSYIPEAKASCYGQAEKPETPLHTLHQFM--- 338

  Fly   269 LNYGGHVNLTEIG---SFTPTEGIQLH------------TWFRTTSTVRRRMDMQHA-------- 310
                  ||:|..|   ||| .||.|:|            .|.:......:.:.::||
  Rat   339 ------VNVTWDGKDLSFT-EEGYQVHPRLVVIVLNKDREWEKVGKWENQTLSLRHAVWPRYKSF 396

  Fly   311 ------------------------------------RVRCMVVVTNKNMTGTLMYYLTHTMSGHI 339
                                                .|.|...|...|.|...|..........|
  Rat   397 SDCEPDDNHLSIVTLEEAPFVIVEDIDPLTETCVRNTVPCRKFVKINNSTNEGMNVKKCCKGFCI 461

  Fly   340 DTMNRFNFNLLMAVRDMFNWTFVLSRTTSWGY----VKNGR--------FDGMIGALIRNETDIG 392
            |.:.:                  ||||..:.|    |.||:        ::||||.::.....:.
  Rat   462 DILKK------------------LSRTVKFTYDLYLVTNGKHGKKVNNVWNGMIGEVVYQRAVMA 508

  Fly   393 GAPIFYWLERHKWIDVAGRSWSSRPCFIFRHPRSTQKDRIVFLQPFTNDVWILIVGCGVLTVFIL 457
            ...:....||.:.:|.:.....:....:......|.... .||:||:..||::        :|::
  Rat   509 VGSLTINEERSEVVDFSVPFVETGISVMVSRSNGTVSPS-AFLEPFSASVWVM--------MFVM 564

  Fly   458 WFLTTIEWKLVPHDGSALIKPKGGAPPRHHYQQQQQQEQVEAPVRPITAVSVVVSKEKVEEKQEE 522
            ..:                                           ::|::|.|
  Rat   565 LLI-------------------------------------------VSAIAVFV----------- 575

  Fly   523 YEDSTPIDAGTLWQRCYQKLNKYIKDRKAKQKKAPERVGLFLESVLFFVGIICQQGLGFSTSF-- 585
            :|..:|:.                .:|...:.|||......:...::.:     .||.|:.|.
  Rat   576 FEYFSPVG----------------YNRNLAKGKAPHGPSFTIGKAIWLL-----WGLVFNNSVPV 619

  Fly   586 -----VSGRCIVITSLLFSFCIYQFYSASIVGTLLMEKPKTIKTLSDLVHSSLKVGMEDILYNRD 645
                 .:.:.:|.....|:......|:|::...::.|:      ..|.|     .|:.|..:.|.
  Rat   620 QNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEE------FVDQV-----TGLSDKKFQRP 673

  Fly   646 YFLHTKDPVSMELYAKKITSVPT-TKENEADEDEPVDPNPVSTDPAKSYRDIVHSHETGAHAKDN 709
               |...|      ..:..:||. :.|.....:.|.....::....:...|.:.|.:||.
  Rat   674 ---HDYSP------PFRFGTVPNGSTERNIRNNYPYMHQYMTRFNQRGVEDALVSLKTGK----- 724

  Fly   710 AASNWLDPETGLLRHLGFAFHVDVAAA-YKIIAETFSEQDICDLTEVS---MFPPQKTVSIMQKN 770
                 ||           ||..|.|.. ||.     ...:.|.|..:.   :|........:||.
  Rat   725 -----LD-----------AFIYDAAVLNYKA-----GRDEGCKLVTIGSGYIFATTGYGIALQKG 768

  Fly   771 SPMRKVISYGLRRVTETGILTYHFNVW-----HSRKPPCVKKIETSDLHVDMDTVSSALLILLFS 830
            ||.::.|...|.:....|.:.....:|     |:.|    .::.:|.|  |:|.::....:|..:
  Rat   769 SPWKRQIDLALLQFVGDGEMEELETLWLTGICHNEK----NEVMSSQL--DIDNMAGVFYMLAAA 827

  Fly   831 YAITLMILGTEILY 844
            .|::|:....|.|:
  Rat   828 MALSLITFIWEHLF 841

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.