Protein Alignment Ir64a and Grik5

DIOPT Version :9

• Sequence 1: NP_647962.1
• Gene: Ir64a / 38616
• FlyBaseID: FBgn0035604
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: XP_006228444.1
• Gene: Grik5 / 24407
• RGDID: 2735
• Length: 980
• Species: Rattus norvegicus
• Alignment Length: 638
• Identity: 117/638 - (18%)
• Similarity: 202/638 - (31%)
• Gaps: 194/638 - (30%)

  Fly   260 TLFDVWNPGLNYGGHVNLTEIGSFTPTEGIQLHTWF-----RTTSTVRRRMDMQHARVRCMVVVT 319
            |..::|..|.:...::.:.|.      :|:.....|     ||..|:|.....:.......|..:
  Rat   335 TSANIWPHGTSLMNYLRMVEY------DGLTGRVEFNSKGQRTNYTLRILEKSRQGHREIGVWYS 393

  Fly   320 NKNM---TGTLMYYLTHTMSGH---IDT-------MNRFNFNLLMA-----------VRDM---- 356
            |:.:   ..||...|:.|::..   :.|       |.|.||..|..           :|::
  Rat   394 NRTLAMNATTLDINLSQTLANKTLVVTTILENPYVMRRPNFQALSGNERFEGFCVDMLRELAELL 458

  Fly   357 -FNWTFVLSRTTSWGYVK-NGRFDGMIGALI-RNETDIGGAPIFYWLERHKWIDVAGRSWSSRPC 418
             |.:...|.....:|..: ||.:.||:|.|| |.:.|:..|......||.|.||.:....:....
  Rat   459 RFRYRLRLVEDGLYGAPEPNGSWTGMVGELINRQKADLAVAAFTITAEREKVIDFSKPFMTLGIS 523

  Fly   419 FIFRHPRSTQKDRIVFLQPFTNDVWI------LIVGCGVLTVFILWFLTTIEWKLVPHDGSALIK 477
            .::|.....:.....||.||:..||:      |.|.|   .:|:...|:..|| ..||
  Rat   524 ILYRVHMGRKPGYFSFLDPFSPAVWLFMLLAYLAVSC---VLFLAARLSPYEW-YNPH------- 577

  Fly   478 PKGGAPPRHHYQQQQQQEQVEAPVRPITAVSVVVSKEKVEEKQEEYEDSTPIDAGTLWQRCYQKL 542
            |...|.|.                              :.|.|....:|       ||
  Rat   578 PCLRARPH------------------------------ILENQYTLGNS-------LW------- 598

  Fly   543 NKYIKDRKAKQKKAPERVGLFLESVLFFVGIICQQGLGFSTSFVSGRCIVITSLLFSFCIYQFYS 607
                                      |.||...|||.......:|.||:......|:..|...|:
  Rat   599 --------------------------FPVGGFMQQGSEIMPRALSTRCVSGVWWAFTLIIISSYT 637

  Fly   608 ASIVGTLLMEKPKT-IKTLSDLVHSSLKVGMEDILYNRDYFLHTKDPVSMELYAKKITSVPTTKE 671
            |::...|.:::.:. :::..||.                      |..::|.......|..|..:
  Rat   638 ANLAAFLTVQRMEVPVESADDLA----------------------DQTNIEYGTIHAGSTMTFFQ 680

  Fly   672 NEADEDEPVDPNPVSTDPAKSYR---DIVHSHETGAHAKDNAASNWLDPETGLLRHLG--FAFHV 731
            |..               .::|:   :.:.|.:.....|..        |.|:.|.|.  :||
  Rat   681 NSR---------------YQTYQRMWNYMQSKQPSVFVKST--------EEGIARVLNSRYAF-- 720

  Fly   732 DVAAAYKIIAETFSEQD---ICDLTEVSMFPPQKTVSI-MQKNSPMRKVISYGLRRVTETGILTY 792
                   ::..|.:|..   .|:||::......|...| |...||.|..|:..:.::.|...|..
  Rat   721 -------LLESTMNEYHRRLNCNLTQIGGLLDTKGYGIGMPLGSPFRDEITLAILQLQENNRLEI 778

  Fly   793 HFNVWHSRKPPCVKKIETSDLHVDMDTVSSALLILLFSYAITLMILGTEILYS 845
            ....|. ....|.|:.:.....:.|:.:....::|:....|.:.:...|.::|
  Rat   779 LKRKWW-EGGRCPKEEDHRAKGLGMENIGGIFVVLICGLIIAVFVAVMEFIWS 830

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir64a	NP_647962.1	Periplasmic_Binding_Protein_Type_2	351..>465	CDD:304360	31/137 (23%)
		Lig_chan	563..828	CDD:278489	48/274 (18%)
Grik5	XP_006228444.1	PBP1_iGluR_Kainate_KA1_2	23..401	CDD:380616	12/71 (17%)
		Periplasmic_Binding_Protein_Type_2	414..785	CDD:389745	94/506 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350064
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740