DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir64a and T25E4.2

DIOPT Version :9

Sequence 1:	NP_647962.1	Gene:	Ir64a / 38616	FlyBaseID:	FBgn0035604	Length:	859	Species:	Drosophila melanogaster
Sequence 2:	NP_001364710.1	Gene:	T25E4.2 / 188897	WormBaseID:	WBGene00020804	Length:	455	Species:	Caenorhabditis elegans

Alignment Length:	257	Identity:	50/257 - (19%)
Similarity:	100/257 - (38%)	Gaps:	54/257 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   561 GLFLESVLFFVGIICQQGLGFSTSFV----SGRCIVITS---LLFSFCIYQFYSASIVGTLLMEK 618
            ||.:.|:|.::.|.|.   |....|:    |..|.::..   ||....|..:|.|.:...||:..
Worm   148 GLRVRSLLDWMFISCS---GIIHQFMFRISSPICALVLIGFWLLCCLVIITYYEAKLKSFLLLSH 209

  Fly   619 PK-TI-KTLSDLVHSSLKVGMEDILYNRDY----FLHTKDPVSMELYAKKITSVPTTKENEAD-- 675
            .: || .||..::.::...|...::..|.|    :.:......::....:|..:..  :::|:
Worm   210 HRGTIFNTLDGVLEAAEHKGWTLVIQERGYTPYLYCNPSQCARLDRLKSRINFIGA--DDDANLL 272

  Fly   676 --EDEPVDPNPVSTDPAKSYRDIVH--SHETGAHAKDNAASNWLDPETGLLRHLGFAFHVDVAAA 736
              :|:.|..:.:::|.|::  ||.:  .|......:|..    :.||     :|.:|.:.:|...
Worm   273 LGQDKHVGFSALASDLAET--DITYFDYHSKILFVRDKI----MAPE-----YLAYAVNKNVKGL 326

  Fly   737 ----YKIIAETFSEQDICDLTEVSMFPPQKTVSIMQKNSPMRKVISYGLRRVTETGILTYHF 794
                .:.:|.|.|.........::.||...:|:...:               |.|.:.|.||
Worm   327 REKFNRAVAYTKSGYGTVRSRYIASFPSYNSVTSQSQ---------------TITVLQTSHF 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir64a	NP_647962.1	Periplasmic_Binding_Protein_Type_2	351..>465	CDD:304360
Ir64a	NP_647962.1	Lig_chan	563..828	CDD:278489	48/255 (19%)
T25E4.2	NP_001364710.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900