Protein Alignment Ir64a and glr-1

DIOPT Version :10

• Sequence 1: NP_647962.1
• Gene: Ir64a / 38616
• FlyBaseID: FBgn0035604
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: NP_498887.2
• Gene: glr-1 / 176204
• WormBaseID: WBGene00001612
• Length: 962
• Species: Caenorhabditis elegans
• Alignment Length: 732
• Identity: 130/732 - (17%)
• Similarity: 229/732 - (31%)
• Gaps: 237/732 - (32%)

  Fly   193 WHGRTQTAEGSGKRDDGEMEEEE-----PPGQQIQATDDEDLPS--IESFLGGMNLYMNTELTLA 250
            |||..:..:.:.....|......     .||.......|...|:  ..||..|..      :.:|
 Worm   323 WHGFAKCLQANDSLFHGTFRHRRFFNRGFPGIYCDPLSDRSHPNRPFSSFEHGKT------IGVA 381

  Fly   251 KRMSEAAHY--TL-----FDVWNPGLNYGGHVNLTEIGSFTPT--EGIQLHTWFRTTSTVRRRMD 306
            .|..:..|.  ||     ||.:....|:  .|::.::.|.|..  ...::..|.:.......|..
 Worm   382 FRNMKIGHKEGTLTGNIEFDRFGNRKNF--DVSIVDLVSNTKATFNSKEVLAWRQGVGFFSNRTV 444

  Fly   307 MQHARV-------RCMVVVTNKNMTGTL-------MYYLTHTMSGHIDTMNRFN---FNLLMAVR 354
            .||:|.       ..::|:||......:       |..||.....     |:|.   .:||..:.
 Worm   445 AQHSRKSQNDHKDNQVIVLTNLVAPFVMIKRECLEMANLTECQGN-----NKFEGFCIDLLKLLA 504

  Fly   355 DM---FNWTFVLSRTTSWGYVKNGRFDGMIGALIRNETDIGGAPIFYWLERHKWIDVAGRSWSSR 416
            |.   ||:...|. |.:.....:|.:|||||.|:........|.:....||.:.:|.:....::.
 Worm   505 DKIEEFNYEIKLG-TKAGSKQADGSWDGMIGELLSGRAHAVVASLTINQERERVVDFSKPFMTTG 568

  Fly   417 PCFIFRHPRSTQKDRIVFLQPFTNDVWILI----VGCGVLTVFILWFLTTIEWKLVPHDGSALIK 477
            ...:.:.|...:.....|:||.:.::|:.|    :|..|: :|::...:..||::..       .
 Worm   569 ISIMIKKPDKQEFSVFSFMQPLSTEIWMYIIFAYIGVSVV-IFLVSRFSPYEWRVEE-------T 625

  Fly   478 PKGGAPPRHHYQQQQQQEQVEAPVRPITAVSVVVSKEKVEEKQEEYEDSTPIDAGTLWQRCYQKL 542
            .:||....:.:                   ||.                     ..||
 Worm   626 SRGGFTISNDF-------------------SVY---------------------NCLW------- 643

  Fly   543 NKYIKDRKAKQKKAPERVGLFLESVLFFVGIICQQGLGFSTSFVSGRCIVITSLLFSFCIYQFYS 607
                                      |.:....|||.......:|||........|:..|...|:
 Worm   644 --------------------------FTLAAFMQQGTDILPRSISGRIASSAWWFFTMIIVSSYT 682

  Fly   608 ASIVGTLLMEKPKT-IKTLSDLV-HSSLKVGMED-------------ILYNR--DYFLHTKDPVS 655
            |::...|.:||.:. |:::.||. .|.:|.|::.             .:|.|  .|......||.
 Worm   683 ANLAAFLTLEKMQAPIESVEDLAKQSKIKYGIQGGGSTASFFKYSSVQIYQRMWRYMESQVPPVF 747

  Fly   656 MELYAKKITSVPTTK-------ENEADEDE----PVDPNPVSTDPAKSYRDIVHSHETGAHAKDN 709
            :..||:.|..|.:.|       |..|:|.|    |.|...|.          .:.:..|......
 Worm   748 VASYAEGIERVRSHKGRYAFLLEATANEYENTRKPCDTMKVG----------ANLNSIGYGIATP 802

  Fly   710 AASNWLDPETGLLRHLGFAFHVDVAAAYKIIAETFSEQDICDLTEVSMFPPQKTVSIMQKNSPMR 774
            ..|:|.|             |:::|    |:|                         :|:...::
 Worm   803 FGSDWKD-------------HINLA----ILA-------------------------LQERGELK 825

  Fly   775 KVISYGLRRVTETGILTYHFNVWHSRKPPCVK--KIETSDLHVDMDTVSSALLILLFSYAITLMI 837
            |:                 .|.|...:..|..  .::.|...:::..|:....||:....|:::.
 Worm   826 KL-----------------ENKWWYDRGQCDAGITVDGSSASLNLSKVAGIFYILMGGMVISMLA 873

  Fly   838 LGTEILYSKWHNRIQLK 854
            ...|.||   .:||:.:
 Worm   874 ALGEFLY---RSRIEAR 887

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir64a	NP_647962.1	Periplasmic_Binding_Protein_Type_2	351..>465	CDD:473866	25/120 (21%)
		Lig_chan	563..828	CDD:459656	53/294 (18%)
glr-1	NP_498887.2	PBP1_iGluR_AMPA	32..442	CDD:380603	23/126 (18%)
		Periplasmic_Binding_Protein_Type_2	457..832	CDD:473866	91/530 (17%)