Protein Alignment Ir64a and glr-3

DIOPT Version :9

• Sequence 1: NP_647962.1
• Gene: Ir64a / 38616
• FlyBaseID: FBgn0035604
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: NP_492017.3
• Gene: glr-3 / 172449
• WormBaseID: WBGene00001614
• Length: 836
• Species: Caenorhabditis elegans
• Alignment Length: 609
• Identity: 113/609 - (18%)
• Similarity: 206/609 - (33%)
• Gaps: 176/609 - (28%)

  Fly   265 WNPGLNYGGHVNLTEIGSFTPTEGIQLHTWFRTTSTVR--------RRMDMQHARVRCMVVVTNK 321
            |.|.   |...|.|            ||.:.||.|..:        ||:....|     ||:.|.
 Worm   348 WAPS---GERSNYT------------LHVYRRTLSFQKFAEWSSRTRRIASSEA-----VVIANS 392

  Fly   322 NMTGTL--------MY----YLTHTMSGHIDTMNRFNFNLLMAVRDMFNWTFVLSRTTSWGY--- 371
            :...||        :|    ::..|.:|   :...:..:||..:.::..:|:.:.:.....|
 Worm   393 SEKLTLEGKHLKISVYLEAPFVMITSNG---SYEGYCIDLLHKIANILKFTYTIQKVRDNAYGSK 454

  Fly   372 VKNGRFDGMIGALIRNETDIGGAPIFYWLERHKWIDVAGRSWSSRPCFIFRHPRSTQKDRIVFLQ 436
            ..||::.||:|.|.|.:.|:..|.:.....|.:.||............:|:.||....|...|:.
 Worm   455 ESNGKWSGMVGELQRGDADLAVASLTISYGRSEVIDFTVPYMHLGISILFKKPRIRDSDWFKFMD 519

  Fly   437 PFTNDVWILIVGCGVLTVFILWFLTTIEWKLVPHDGSALIKPKGGAPPRHHYQQQQQQEQVEAPV 501
            |.:..|||:......:....:|.:.    |:.|:                        ||.|.
 Worm   520 PLSTQVWIMTFASYFVVSVAIWIIA----KISPY------------------------EQFER-- 554

  Fly   502 RPITAVSVVVSKEKVEEKQEEYEDSTPIDAGTLWQRCYQKLNKYIKDRKAKQKKAPERVGLFLES 566
                           :|...:|:   |:|            |::                ....|
 Worm   555 ---------------DEDNGQYK---PVD------------NQF----------------SLRNS 573

  Fly   567 VLFFVGIICQQGLGFSTSFVSGRCIVITSLLFSFCIYQFYSASIVGTLLMEKPKT-IKTLSDL-V 629
            ..|.|..:.|||........|.|.:......|:..:...|:|::...|...:.:| |:...|| .
 Worm   574 FWFTVCSLMQQGSELCPRAASTRLLTGIWWFFALILISSYTANLAAVLTTRRMETPIENADDLAA 638

  Fly   630 HSSLKVGMEDILYNRDYFLHTKDPVSMELYAKKITSVPTTKENEADEDEPVDPNPVSTDPAKSYR 694
            .:.:|.|.........:|..:|    :|.|.:..                   ..:|:.|..
 Worm   639 QTKIKYGTLGRGSTMSFFNESK----IETYERMW-------------------QLMSSSPGL--- 677

  Fly   695 DIVHSHETG-AHAKDNAASNWLDPETGLLRHLGFAFHVDVAAAYKIIAETFSEQDICDLTEVSMF 758
             .|.|.:.| |..|.:                .:|:.::.:     :.|...|:| |:|.::...
 Worm   678 -FVQSSKEGIARVKSS----------------DYAYLMESS-----MLEYAVERD-CELMQIGGL 719

  Fly   759 PPQKTVSI-MQKNSPMRKVISYGLRRVTETGILTYHFNVWHSRKPPCVKKIETSDLHVDMDTVSS 822
            ..||...| :.|.||.|::||..:.|:.|...||.....|...|....::.:..| ..|.:::..
 Worm   720 IDQKGYGIGLPKGSPYRELISTAILRLQEKTELTELKEKWWKDKSVVCEQPKRKD-QDDGESIGG 783

  Fly   823 ALLILLFSYAITLMILGTEILYSK 846
            ..:||:....:|.:::..|::.::
 Worm   784 IFIILVVGLVLTAVLVIFELITTR 807

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir64a	NP_647962.1	Periplasmic_Binding_Protein_Type_2	351..>465	CDD:304360	24/116 (21%)
		Lig_chan	563..828	CDD:278489	53/268 (20%)
glr-3	NP_492017.3	PBP1_iGluR_non_NMDA-like	21..385	CDD:380591	12/51 (24%)
		Periplasmic_Binding_Protein_Type_2	401..761	CDD:419667	88/487 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910