Protein Alignment Ir64a and gria3a

DIOPT Version :10

• Sequence 1: NP_647962.1
• Gene: Ir64a / 38616
• FlyBaseID: FBgn0035604
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: XP_073805840.1
• Gene: gria3a / 170452
• ZFINID: ZDB-GENE-020125-5
• Length: 940
• Species: Danio rerio
• Alignment Length: 1009
• Identity: 178/1009 - (17%)
• Similarity: 308/1009 - (30%)
• Gaps: 342/1009 - (33%)

  Fly    67 LQT----PNQI--------PNAAEHRDAFAAKNFQLIKSLYESELFVRIVLLDVLAQSPTSGRPN 119
            |||    ||||        ....||      ..|:....||.:.        ..:.:.|.....|
Zfish    17 LQTQAGFPNQINIGGLFMRSTVQEH------SAFRFAVQLYNTN--------QNITEKPFHLNYN 67

  Fly   120 RPGNGPTGGFSQTPSQAQSNSEWLEGVLRMEALRQIAVVDLACGAVSRRFL-------------- 170
            ......:..||.|.:.....|..:..:......|.:..:...|||:...|:
Zfish    68 VDNLESSNSFSVTHAFCSQFSRGVYAIFGFYDRRSMNTLTSFCGALHTSFITPSFPTDTDVQFVL 132

  Fly   171 --------ELASAKMLYS-EKFHWL------------LIEDFAWHGRTQTAEGSGKRDD----GE 210
                    .|.|....|. |||.:|            ::|....:....||...|...|    ..
Zfish   133 QMRPSLRGALLSLLAHYKWEKFVYLYDTDRGFSILQAIMESAVMNNWQVTARSVGNIVDPLEYRR 197

  Fly   211 MEEEEPPGQQIQATDDEDLPSIESFLGGMNLYMNTELTLAKRMSEAAHYTLFDV--WNPGLN--Y 271
            :.||....|:.:...|.::..|.|.|        .::.:|.:.|...||.|.::  .|..|:  :
Zfish   198 IIEEMDRRQEKRFLIDCEVERINSIL--------EQVVIAGKNSRGYHYILANLGFTNMSLDKVF 254

  Fly   272 GGHVNLTEIGSFTPTEGIQ---LHTWFRT---------------TSTV----------------R 302
            .|..|:|......|...|.   |..|.|.               ||.:                |
Zfish   255 SGGANITGFQIINPDSPIVQQFLQRWERLDEREFPESRSSPLKYTSALTHDAILVIAEAFRYLRR 319

  Fly   303 RRMDMQHAR-------------------VRCMVVVTNKNMTGTLMY--------YLTHTMS---- 336
            :|:|:....                   .|.:.:|..:.|||.:.:        |......
Zfish   320 QRVDISRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNIQFDSFGRRSNYTVDVYEMKPG 384

  Fly   337 -----GHIDTMNRFNF--------------NLLMAVRDMFNWTFVLSRTTSW---------GY-- 371
                 |:.:...:|.:              |..:.|..:....:|:.:....         ||
Zfish   385 GARKIGYWNEFEKFVYIVEQQVTNESSSVENRTIVVTTIMEAPYVMYKRNYMQLEGNDRYEGYCV 449

  Fly   372 ------------------VKNGRF----------DGMIGALIRNETDIGGAPIFYWLERHKWIDV 408
                              |.:|::          :||:|.|:....||..||:...|.|.:.||.
Zfish   450 DLASEIAKHVGIKYKLSIVADGKYGARDPETKTWNGMVGELVYGRADIAVAPLTITLVREEVIDF 514

  Fly   409 AGRSWSSRPCFIFRHPRSTQKDRIVFLQPFTNDVWILIV----GCGVLTVFILWFLTTIEWKLVP 469
            :....|.....:.:.|:.::.....||.|...::|:.||    |..|: :|::...:..||.|
Zfish   515 SKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVV-LFLVSRFSPYEWHL-- 576

  Fly   470 HDGSALIKPKGGAPPRHHYQQQQQQEQVEAPVRPITAVSVVVSKEKVEEKQEEYEDSTPIDAGTL 534
                                                           ::.:|..:..||.|
Zfish   577 -----------------------------------------------DDNEETKDPQTPPD---- 590

  Fly   535 WQRCYQKLNKYIKDRKAKQKKAPERVGLFLESVLFFVGIICQQGLGFSTSFVSGRCIVITSLLFS 599
                                 .|...|:| .|:.|.:|...|||...|...:|||.:......|:
Zfish   591 ---------------------PPNDFGIF-NSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFT 633

  Fly   600 FCIYQFYSASIVGTLLMEK-PKTIKTLSDLV-HSSLKVGMEDILYNRDYFLHTKDPVSMELY--- 659
            ..|...|:|::...|.:|: ...|::..||. .:.:..|..|....:::|..:|..|..:::
Zfish   634 LIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYM 698

  Fly   660 --AKKITSVPTTKENEA---------------------DEDEPVDPNPVSTD-PAKSYRDIVHSH 700
              |:....|.||.:..|                     ::.:|.|...|..: .:|.| .:....
Zfish   699 KSAEPSVFVKTTPDGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGY-GVATPK 762

  Fly   701 ETGAHAKDNAASNWLDPETGLLRHLGFAFHVDVAAAYKIIAETFSEQDIC-----DLTEVSMFPP 760
            .:...:..|.|...|: |.|||.              |:..:.:.::..|     |....:..|
Zfish   763 GSALRSAVNLAVLKLN-EQGLLD--------------KLKNKWWYDKGECGSGGGDSKHKARCP- 811

  Fly   761 QKTVSIMQKNSPMRKVISYGLRRVTETGILTYHFNVWHSRKPPC-----VKKIETSDLHVDMDTV 820
              |||:..  :.:|..::..:.:::|.|||....|.|...|..|     ..|.:||.|  .:..|
Zfish   812 --TVSLWL--TDIRTPVNLAVLKLSEQGILDKLKNKWWYDKGECGTKDSGSKDKTSAL--SLSNV 870

  Fly   821 SSALLILLFSYAITLMILGTEILYSKWHNRIQLK 854
            :....||:....:.:.:...|..|.......:||
Zfish   871 AGVFYILVGGLGLAMTVALVEFCYKSHQETKRLK 904

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir64a	NP_647962.1	Periplasmic_Binding_Protein_Type_2	351..>465	CDD:473866	29/156 (19%)
		Lig_chan	563..828	CDD:459656	64/303 (21%)
gria3a	XP_073805840.1	None