Protein Alignment Ir64a and gria2b

DIOPT Version :10

• Sequence 1: NP_647962.1
• Gene: Ir64a / 38616
• FlyBaseID: FBgn0035604
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: XP_068069253.1
• Gene: gria2b / 170451
• ZFINID: ZDB-GENE-020125-4
• Length: 944
• Species: Danio rerio
• Alignment Length: 630
• Identity: 110/630 - (17%)
• Similarity: 201/630 - (31%)
• Gaps: 203/630 - (32%)

  Fly   262 FDVWNPGLNYGGHVNLTEIGSFTPTEGIQLHTWFRTTSTVRRRMDM-----QHARVRCMVVVT-- 319
            ||.:...:||  .||:.|:.|   ...:::..|......|..:.|:     .....:.::|.|
Zfish   360 FDQYGKRVNY--TVNVMELKS---NGAVKIGYWNEVDKMVVTKSDLFPNDTMGLENKTVIVTTIL 419

  Fly   320 ----------------NKNMTGTLMYYLTHTMSGHIDTMNRFNFNLLM------AVRDMFNWTFV 362
                            |:...|..:     .::..|.....|.:.|.:      ..||
Zfish   420 EAPYVMLKKNADLFMDNERYEGYCV-----DLAAEIAKHCGFKYQLKIVGDGKYGARD------- 472

  Fly   363 LSRTTSWGYVKNGRFDGMIGALIRNETDIGGAPIFYWLERHKWIDVAGRSWSSRPCFIFRHPRST 427
             :.|..|        :||:|.|:..:.||..||:...|.|.:.||.:....|.....:.:.|:.:
Zfish   473 -AETKIW--------NGMVGELVYGKADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKS 528

  Fly   428 QKDRIVFLQPFTNDVWILIV----GCGVLTVFILWFLTTIEWKLVPHDGSALIKPKGGAPPRHHY 488
            :.....||.|...::|:.||    |..|: :|::...:..||
Zfish   529 KPGVFSFLDPLAYEIWMCIVFAYIGVSVV-LFLVSRFSPYEW----------------------- 569

  Fly   489 QQQQQQEQVEAPVRPITAVSVVVSKEKVEEKQEEYEDSTPIDAGTLWQRCYQKLNKYIKDRKAKQ 553
                                          ..|||||.                       :.:.
Zfish   570 ------------------------------HTEEYEDG-----------------------QIQT 581

  Fly   554 KKAPERVGLFLESVLFFVGIICQQGLGFSTSFVSGRCIVITSLLFSFCIYQFYSASIVGTLLMEK 618
            .::....|:| .|:.|.:|...:||...|...:|||.:......|:..|...|:|::...|.:|:
Zfish   582 NESTNEFGIF-NSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVER 645

  Fly   619 -PKTIKTLSDLV-HSSLKVGMEDILYNRDYFLHTKDPVSMELYAKKITSVPTTKENEADEDEPVD 681
             ...|::..||. .:.:..|..|....:::|..:|    :.|:.|..|.:           :..:
Zfish   646 MVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSK----IALFDKMWTYM-----------KGAE 695

  Fly   682 PNPVSTDPAKSYRDIVHSHETGAHAKDNAASNWLDPETGLLRHLGFAFHVDVAAAYKIIAETFSE 746
            |:......|:....:..|....|:..::..:.:::                             :
Zfish   696 PSVFVKTTAEGVMRVRKSKGKYAYLLESTMNEYIE-----------------------------Q 731

  Fly   747 QDICDLTEVSMFPPQKTVSI-MQKNSPMRKVISYGLRRVTETGILTYHFNVWHSRKPPC------ 804
            :..||..:|......|...| ..|.|.:|..::..:.::.|.|:|....|.|...|..|
Zfish   732 RKPCDTMKVGGNLDSKGYGIATPKGSSLRNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGD 796

  Fly   805 --VKKIETSDLHVDMDTVSSALLILLFSYAITLMILGTEILYSKW 847
              |...|.|      |.....|.:|..|...||     :.|.:||
Zfish   797 SKVSPREQS------DGTPVNLAVLKLSEQGTL-----DKLKNKW 830

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir64a	NP_647962.1	Periplasmic_Binding_Protein_Type_2	351..>465	CDD:473866	27/123 (22%)
		Lig_chan	563..828	CDD:459656	50/275 (18%)
gria2b	XP_068069253.1	PBP1_iGluR_AMPA_GluR2	27..397	CDD:380612	10/41 (24%)
		PBP2_iGluR_AMPA	410..790	CDD:270433	86/522 (16%)