Protein Alignment Ir64a and grin2ba

DIOPT Version :10

• Sequence 1: NP_647962.1
• Gene: Ir64a / 38616
• FlyBaseID: FBgn0035604
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: NP_001429729.1
• Gene: grin2ba / 110438919
• ZFINID: ZDB-GENE-090821-2
• Length: 1606
• Species: Danio rerio
• Alignment Length: 900
• Identity: 151/900 - (16%)
• Similarity: 279/900 - (31%)
• Gaps: 311/900 - (34%)

  Fly    16 LPEHELLELELDYGLAEPQR-TSLLQSSLILQFSQDYKHIPRITYFTCQKPHLQ-------TPNQ 72
            |.|..||::.:|.|.|:.|. ...|||.:||.:|.  |....|.:.......|.       .|:.
Zfish   247 LEEVLLLDMSVDDGDAKIQNLLKKLQSPVILLYST--KEEANIIFQVAHSVGLTGYGYTWIVPSL 309

  Fly    73 IPNAAEHRDAFAAKNFQLIKSLYESELFVRIVLLDVLAQSPTSGRPNRPGNGPTGGFSQTPSQAQ 137
            :...|:|                                        .|...|||..|      .
Zfish   310 VAGDADH----------------------------------------IPAEFPTGMIS------V 328

  Fly   138 SNSEWLEGVLRMEALRQIAVVDLACGAVSRRFLELASAKMLYSEKFHWLLIEDFAWHG---RTQT 199
            |..||..|   :||..:..|..:|          .|::.|:.....|.||..:  .||   :...
Zfish   329 SYDEWDYG---LEARVRDGVAVIA----------TATSTMMMDRGPHTLLKSE--CHGAPDKKSP 378

  Fly   200 AEGSGKRDDGEMEEEEPPGQQIQATDDEDLPSIESFLGGMNLYMNTELTLAKRMSEAAHYTLFDV 264
            ..|:.......:......|:.:..::|           |..::....:.|..:..:
Zfish   379 MTGNNNEVLRYLMNVTFEGRNLSFSED-----------GYQMHPKLVIILLDKERQ--------- 423

  Fly   265 WNPGLNYGGHVNLTEIGSFTPTEGIQLHTW--FRTTSTVRRRMDMQHARVRCM-----VVVTNKN 322
            |:       .|...|.||.:    ::.|.|  |...|....|.| .|..:..:     |:|.:.:
Zfish   424 WD-------RVGKWENGSLS----MKYHVWPRFELYSGPEARED-DHLSIVTLEEAPFVIVEDVD 476

  Fly   323 -MTGTLM--------------------YYLTHTMSGHIDTMNRFNFNLLMAVRDMFNWTFVLSRT 366
             ::||.|                    .|:.....|       |..::|..:.....:|:.|...
Zfish   477 PLSGTCMRNTVPCRKQLKALNQTQDSAVYIKRCCKG-------FCIDILKKIAKNVKFTYDLYLV 534

  Fly   367 TSWGYVK--NGRFDGMIGALIRNETDIGGAPIFYWLERHKWIDVAGRSWSSRPCFIFRHPRSTQK 429
            |:..:.|  ||.::||:|.::.....:....:....||.:.||.:.....:....:......|..
Zfish   535 TNGKHGKKINGTWNGMVGEVVLKNAHMAVGSLTINEERSEVIDFSVPFIETGISVMVSRSNGTVS 599

  Fly   430 DRIVFLQPFTNDVWILIVGCGVLTVFILWFLTTIEWKLVPHDGSALIKPKGGAPPRHHYQQQQQQ 494
            .. .||:||:.||||:        :|::..|
Zfish   600 PS-AFLEPFSADVWIM--------MFVMLLL---------------------------------- 621

  Fly   495 EQVEAPVRPITAVSVVVSKEKVEEKQEEYEDSTPIDAGTLWQRCYQKLNKYIKDRKAKQKKAPER 559
                     ::|::|.:           :|..:|:.    :.||       :.|  .::...|.
Zfish   622 ---------VSAIAVFI-----------FEYFSPVG----YNRC-------LAD--GREAGGPS- 652

  Fly   560 VGLFLESVLFFVG--IICQQGLGFSTSF-------VSGRCIVITSLLFSFCIYQFYSASIVGTLL 615
                     |.:|  |....||.|:.|.       .:.:.:|.....|:......|:|::...::
Zfish   653 ---------FTIGKAIWLLWGLVFNNSVPVQNPRGTTSKIMVSVWAFFAVIFLASYTANLAAFMI 708

  Fly   616 MEKPKTIKTLSDLVHSSLKVGMEDILYNRDYFLHTKDPVSMELYAKKITSVPTTK-ENEADEDEP 679
            .|:                                        |..:::.:...| :|..|...|
Zfish   709 QEE----------------------------------------YVDQVSGLSDKKFQNPNDFSPP 733

  Fly   680 -----VDPNPVSTDPAKSYRDIVHSHETGAHAKDNAASNWLDPETGLLRHLGFAFHVDVAAAYKI 739
                 |.......:...:||| :||:....|.: |........:||.|.    ||..|.|    :
Zfish   734 FRFGTVPNGSTERNIRNNYRD-MHSYMVKFHQR-NVVEALESLKTGKLD----AFIYDAA----V 788

  Fly   740 IAETFSEQDICDLTEV---SMFPPQKTVSIMQKNSPMRKVISYGLRRVTETGILTYHFNVW---- 797
            :.......:.|.|..:   .:|........:||:|..::.:...:.::...|.:.....:|
Zfish   789 LNYMAGRDEGCKLVTIGSGKVFASTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELEALWLTGI 853

  Fly   798 -HSRKPPCVKKIETSDLHVDMDTVSSALLILLFSYAITLM-ILGTEILYSKWHNR 850
             |..|    .::.:|.|  |:|.::....:|..:.|::|: .:...:.|  ||.|
Zfish   854 CHHEK----NEVMSSQL--DVDNMAGVFYMLGAAMALSLITFIAEHVFY--WHMR 900

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir64a	NP_647962.1	Periplasmic_Binding_Protein_Type_2	351..>465	CDD:473866	24/115 (21%)
		Lig_chan	563..828	CDD:459656	46/287 (16%)
grin2ba	NP_001429729.1	None