Protein Alignment Ir64a and gria3

DIOPT Version :9

• Sequence 1: NP_647962.1
• Gene: Ir64a / 38616
• FlyBaseID: FBgn0035604
• Length: 859
• Species: Drosophila melanogaster
• Sequence 2: NP_001106494.1
• Gene: gria3 / 100127683
• XenbaseID: XB-GENE-1010483
• Length: 887
• Species: Xenopus tropicalis
• Alignment Length: 630
• Identity: 110/630 - (17%)
• Similarity: 206/630 - (32%)
• Gaps: 180/630 - (28%)

  Fly   265 WNPGLNYGGHVNLTEIGSFTPTEGIQLHTW----------FRTTSTVRRRMDMQHARVRCMVV-- 317
            |:.|::....:.:.::...  |..||..|:          :..|:|..|::...:...|.:..
 Frog   342 WSQGIDIERALKMVQVQGM--TGNIQFDTYGRRTNYTIDVYEMTATKPRKVGHWNEYERFVPAPD 404

  Fly   318 ---------VTNKNMTGT-------LMYYLTHTMSGHIDTMNRFNFNLLMAVRDMFNWTFVLSRT 366
                     |.||.:..|       :|....|.:....|....:..:|...:.......:.||
 Frog   405 QQPTNESSSVENKTIIVTTILENPYVMKKKNHELLDGNDKYEGYCVDLASEIAKHVGIKYKLS-- 467

  Fly   367 TSWGYVKNGRF----------DGMIGALIRNETDIGGAPIFYWLERHKWIDVAGRSWSSRPCFIF 421
                .|::|::          :||:|.|:....||..||:...|.|.:.||.:....|.....:.
 Frog   468 ----IVEDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMI 528

  Fly   422 RHPRSTQKDRIVFLQPFTNDVWILIV----GCGVLTVFILWFLTTIEWKLVPHDGSALIKPKGGA 482
            :.|:.::.....||.|...::|:.||    |..|: :|::...:..||.|
 Frog   529 KKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVV-LFLVSRFSPYEWHL--------------- 577

  Fly   483 PPRHHYQQQQQQEQVEAPVRPITAVSVVVSKEKVEEKQEEYEDSTPIDAGTLWQRCYQKLNKYIK 547
                                              |:..|..:...|.|
 Frog   578 ----------------------------------EDTDEARDPQNPPD----------------- 591

  Fly   548 DRKAKQKKAPERVGLFLESVLFFVGIICQQGLGFSTSFVSGRCIVITSLLFSFCIYQFYSASIVG 612
                    .|...|:| .|:.|.:|...|||...|...:|||.:......|:..|...|:|::..
 Frog   592 --------PPNEFGIF-NSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAA 647

  Fly   613 TLLMEK-PKTIKTLSDLV-HSSLKVGMEDILYNRDYFLHTKDPVSMELYAKKITSVPTTKENEAD 675
            .|.:|: ...|::..||. .:.:..|..|....:::|..:|..|..::::...::.|:......|
 Frog   648 FLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTD 712

  Fly   676 EDEPVDPNPVSTDPAKSYRDIVHSHETGAHAKDNAASNWLDPETGLLRHLGFAFHVDVAAAYKII 740
            :..                         |..:.:...              |||.::     ..:
 Frog   713 DGV-------------------------ARVRKSKGK--------------FAFLLE-----STM 733

  Fly   741 AETFSEQDICDLTEVSMFPPQKTVSI-MQKNSPMRKVISYGLRRVTETGILTYHFNVWHSRKPPC 804
            .|...::..||..:|......|...: ..|.|.:...::..:.:::|.|||....|.|...|..|
 Frog   734 NEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALGTPVNLAVLKLSEQGILDKLKNKWWYDKGEC 798

  Fly   805 -----VKKIETSDLHVDMDTVSSALLILLFSYAITLMILGTEILY 844
                 ..|.:||.|  .:..|:....||:....:.:|:...|..|
 Frog   799 GAKDSGSKDKTSAL--SLSNVAGVFYILVGGLGLAMMVALIEFCY 841

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir64a	NP_647962.1	Periplasmic_Binding_Protein_Type_2	351..>465	CDD:304360	27/127 (21%)
		Lig_chan	563..828	CDD:278489	52/272 (19%)
gria3	NP_001106494.1	Periplasmic_Binding_Protein_Type_1	29..400	CDD:324556	10/59 (17%)
		PBP2_iGluR_AMPA	416..798	CDD:270433	88/507 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100