DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Membrin and Gosr2

DIOPT Version :9

Sequence 1:	NP_647960.1	Gene:	Membrin / 38614	FlyBaseID:	FBgn0260856	Length:	216	Species:	Drosophila melanogaster
Sequence 2:	NP_113873.1	Gene:	Gosr2 / 64154	RGDID:	62079	Length:	212	Species:	Rattus norvegicus

Alignment Length:	214	Identity:	92/214 - (42%)
Similarity:	139/214 - (64%)	Gaps:	3/214 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MESLYHQTNNVVKDIERDFQRLSQLSAQESLDVENGIQLKITQANANCDRLDVLLYKVPPSQRQS 65
            ||.||.||:..|.:|:....||.....|....|||.||..|.|..::.:||::|..|.||::||:
  Rat     1 MEPLYQQTHKQVHEIQSHMGRLETADKQSVHLVENEIQASIDQIFSHLERLEILSSKEPPNRRQN 65

  Fly    66 SKLRVDQLKYDLRHLQTSLQTARERRQRRMQEISEREQLLNHRFTANSAQPEETRLQLDYELQHH 130
            :||||||||||::||||:|:..:.|||.:.|:..:|::||:..||.|.:   :|.:.:|..||.:
  Rat    66 AKLRVDQLKYDVQHLQTALRNFQHRRQAKEQQERQRDELLSRTFTTNDS---DTTIPMDESLQFN 127

  Fly   131 TQLGNAHRGVDDMIASGSGILESLISQRMTLGGAHKRIQAIGSTLGLSNHTMKLIERRLVEDRRI 195
            :.|.|.|.|:||:|..|..|||.|.:||:||.|..|:|..|.:.|||||..|:|||:|..:|:..
  Rat   128 SSLQNIHHGMDDLIGGGHSILEGLRAQRLTLKGTQKKILDIANMLGLSNTVMRLIEKRAFQDKYF 192

  Fly   196 FIGGVVVTLLIIALIIYFL 214
            .|||:::|..::.|::.:|
  Rat   193 MIGGMLLTCAVMFLVVQYL 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Membrin	NP_647960.1	SNARE_GS27	124..188	CDD:277216	32/63 (51%)
Gosr2	NP_113873.1	IxM motif, signal for cargo packaging into COPII-coated vesicles. /evidence=ECO:0000250\|UniProtKB:O14653	118..120		0/1 (0%)
Gosr2	NP_113873.1	SNARE_GS27	120..185	CDD:277216	32/64 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	99	1.000	Domainoid score	I6938
eggNOG	1	0.900	-	-		E1_KOG3251
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37907
Inparanoid	1	1.050	176	1.000	Inparanoid score	I3948
OMA	1	1.010	-	-		QHG55230
OrthoDB	1	1.010	-	-		D1139640at2759
OrthoFinder	1	1.000	-	-		FOG0003803
OrthoInspector	1	1.000	-	-		oto98347
orthoMCL	1	0.900	-	-		OOG6_102735
Panther	1	1.100	-	-	LDO	PTHR21230
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4845
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840