DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Membrin and gosr2

DIOPT Version :9

Sequence 1:	NP_647960.1	Gene:	Membrin / 38614	FlyBaseID:	FBgn0260856	Length:	216	Species:	Drosophila melanogaster
Sequence 2:	NP_955982.1	Gene:	gosr2 / 324569	ZFINID:	ZDB-GENE-030131-3290	Length:	212	Species:	Danio rerio

Alignment Length:	214	Identity:	91/214 - (42%)
Similarity:	141/214 - (65%)	Gaps:	3/214 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MESLYHQTNNVVKDIERDFQRLSQLSAQESLDVENGIQLKITQANANCDRLDVLLYKVPPSQRQS 65
            ||:||||||..:::::....||.:...|....:||.:|.:|.|.....:||::|..|.||::||:
Zfish     1 METLYHQTNKQIQEVQSQMGRLEKTDRQSVHLLENELQARIDQIFNQLERLEILASKEPPNRRQN 65

  Fly    66 SKLRVDQLKYDLRHLQTSLQTARERRQRRMQEISEREQLLNHRFTANSAQPEETRLQLDYELQHH 130
            :||||||||||::||||:|:..:.||.....:..|||:||:..||.|.|   :|.:.:|..||.:
Zfish    66 AKLRVDQLKYDVQHLQTALRNFQHRRYAHEAQEREREELLSRSFTTNDA---DTSIPIDETLQFN 127

  Fly   131 TQLGNAHRGVDDMIASGSGILESLISQRMTLGGAHKRIQAIGSTLGLSNHTMKLIERRLVEDRRI 195
            :.|.|||||:||::.|||.||..|..||.||.|.||::..:.:.|||||..|:|||:|..:|:.|
Zfish   128 SSLQNAHRGMDDLLGSGSSILNGLRDQRSTLKGTHKKMLDVANMLGLSNTVMRLIEKRASQDKFI 192

  Fly   196 FIGGVVVTLLIIALIIYFL 214
            .:.|::.|.:::.|::.:|
Zfish   193 MMAGMLATCVVMFLVVKYL 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Membrin	NP_647960.1	SNARE_GS27	124..188	CDD:277216	33/63 (52%)
gosr2	NP_955982.1	SNARE_GS27	120..185	CDD:277216	33/64 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	102	1.000	Domainoid score	I6853
eggNOG	1	0.900	-	-		E1_KOG3251
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37907
Inparanoid	1	1.050	180	1.000	Inparanoid score	I3997
OMA	1	1.010	-	-		QHG55230
OrthoDB	1	1.010	-	-		D1139640at2759
OrthoFinder	1	1.000	-	-		FOG0003803
OrthoInspector	1	1.000	-	-		oto41648
orthoMCL	1	0.900	-	-		OOG6_102735
Panther	1	1.100	-	-	LDO	PTHR21230
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4591
SonicParanoid	1	1.000	-	-		X4845
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.870