DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyt-c1 and cyc1

DIOPT Version :9

Sequence 1:	NP_001246637.1	Gene:	Cyt-c1 / 38612	FlyBaseID:	FBgn0035600	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_001032470.1	Gene:	cyc1 / 564379	ZFINID:	ZDB-GENE-031105-2	Length:	307	Species:	Danio rerio

Alignment Length:	297	Identity:	185/297 - (62%)
Similarity:	218/297 - (73%)	Gaps:	6/297 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 GLRLLKSAPALSLQQAKNLSSAGSWASGNKKLIGALGAITGGVGALIYALEQSVQASGGEVHSPA 74
            |..||.::.|....:|.  .|..|...|.|..:..:|.:|.|...|...|:|||:||..|:|.|.
Zfish    13 GRTLLNTSKAFHTPRAS--MSFASLPKGKKIALTTIGVLTTGGAGLALMLQQSVKASDLELHPPT 75

  Fly    75 QLWNHKGLFDALDHQSVRRGYEVYKQVCSACHSMQYIAYRNLVGVTHTEAEAKAEAEQITVKDGP 139
            ..|:|.|...:|||.||||||:||||||||||||:|:|:||||||:|||.|.|..||:|.|.|||
Zfish    76 YPWSHGGFLSSLDHASVRRGYQVYKQVCSACHSMEYLAFRNLVGVSHTEDEVKTLAEEIEVVDGP 140

  Fly   140 DDTGNYYTRPGKLSDYFPSPYPNEEAARAANNGAYPPDLSYIVSARKGGEDYIFSLLTGYHDAPA 204
            ||.|..:|||||||||||.||.|.||||||||||.||||||||:||.|||||:|||||||.|.||
Zfish   141 DDNGEMFTRPGKLSDYFPKPYANPEAARAANNGALPPDLSYIVNARHGGEDYVFSLLTGYCDPPA 205

  Fly   205 GVVLREGQYFNPYFPGGAISMAQVLYNEVIEYEDGTPPTQSQLAKDVATFLKWTSEPEHDDRKQL 269
            ||.||||.|:||||||.||.||..:||||:||:||||.|.||:||||.|||:|.:||||||||::
Zfish   206 GVSLREGLYYNPYFPGQAIGMAPPIYNEVLEYDDGTPATMSQVAKDVCTFLRWAAEPEHDDRKRM 270

  Fly   270 LIKVIGILG--FLTVISYYIKRHKWSSLKSRKIVFVP 304
            .:||  :||  .|..:.|||||||||.||||||.:.|
Zfish   271 GLKV--LLGGALLIPLIYYIKRHKWSVLKSRKIAYRP 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyt-c1	NP_001246637.1	CYT1	69..296	CDD:225413	159/228 (70%)
Cyt-c1	NP_001246637.1	Cytochrom_C1	77..295	CDD:280350	156/219 (71%)
cyc1	NP_001032470.1	CYT1	66..297	CDD:225413	161/232 (69%)
cyc1	NP_001032470.1	Cytochrom_C1	78..296	CDD:280350	156/219 (71%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590048
Domainoid	1	1.000	331	1.000	Domainoid score	I1128
eggNOG	1	0.900	-	-		E1_COG2857
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55617
Inparanoid	1	1.050	370	1.000	Inparanoid score	I2087
OMA	1	1.010	-	-		QHG54185
OrthoDB	1	1.010	-	-		D439021at33208
OrthoFinder	1	1.000	-	-		FOG0003553
OrthoInspector	1	1.000	-	-		otm24321
orthoMCL	1	0.900	-	-		OOG6_102032
Panther	1	1.100	-	-	LDO	PTHR10266
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R278
SonicParanoid	1	1.000	-	-		X2430
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800