DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyt-c1 and cyt1

DIOPT Version :9

Sequence 1:	NP_001246637.1	Gene:	Cyt-c1 / 38612	FlyBaseID:	FBgn0035600	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_595846.1	Gene:	cyt1 / 2540456	PomBaseID:	SPBC29A3.18	Length:	307	Species:	Schizosaccharomyces pombe

Alignment Length:	285	Identity:	141/285 - (49%)
Similarity:	189/285 - (66%)	Gaps:	11/285 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 QQAKNLSSAGSWASGNKKLIGALGAITGGVGALIY-----ALEQSVQASGGEVHSPAQLWNHKGL 82
            |.|:...|.||    |..|:.: ..::.|:.||.|     :|........| :|.....|....:
pombe    24 QNAQKTHSKGS----NIALVSS-SLLSVGMIALYYNVYGPSLSAGTPKEEG-LHFIQHDWPQSKV 82

  Fly    83 FDALDHQSVRRGYEVYKQVCSACHSMQYIAYRNLVGVTHTEAEAKAEAEQITVKDGPDDTGNYYT 147
            ....||.|:|||::||::|||||||:..||:|:|||||||..|||..|.::..:|||||.||.:.
pombe    83 LSGFDHASLRRGFQVYREVCSACHSLNLIAWRHLVGVTHTADEAKQMASEVEYEDGPDDEGNMFK 147

  Fly   148 RPGKLSDYFPSPYPNEEAARAANNGAYPPDLSYIVSARKGGEDYIFSLLTGYHDAPAGVVLREGQ 212
            |||||||:.|.||||.|||||:||||.|||||.:|..|.||:|||:||||||.:.||||.:.:|.
pombe   148 RPGKLSDFLPPPYPNVEAARASNNGAAPPDLSCVVRGRHGGQDYIYSLLTGYTEPPAGVEVPDGM 212

  Fly   213 YFNPYFPGGAISMAQVLYNEVIEYEDGTPPTQSQLAKDVATFLKWTSEPEHDDRKQLLIKVIGIL 277
            .|||:|||..|:||:.|:::.:|:|||||.|.:|.||||..||.|.||||.|.||::..:||.:|
pombe   213 NFNPFFPGTQIAMARPLFDDAVEFEDGTPATTAQAAKDVVNFLHWASEPELDIRKKMGFQVITVL 277

  Fly   278 GFLTVISYYIKRHKWSSLKSRKIVF 302
            ..||.:|.:.||.||:.:|:|||.:
pombe   278 TILTALSMWYKRFKWTPIKNRKIFY 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyt-c1	NP_001246637.1	CYT1	69..296	CDD:225413	124/226 (55%)
Cyt-c1	NP_001246637.1	Cytochrom_C1	77..295	CDD:280350	123/217 (57%)
cyt1	NP_595846.1	CYT1	35..296	CDD:225413	132/262 (50%)
cyt1	NP_595846.1	Cytochrom_C1	77..295	CDD:280350	123/217 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	268	1.000	Domainoid score	I340
eggNOG	1	0.900	-	-		E1_COG2857
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55617
Inparanoid	1	1.050	277	1.000	Inparanoid score	I684
OMA	1	1.010	-	-		QHG54185
OrthoFinder	1	1.000	-	-		FOG0003553
OrthoInspector	1	1.000	-	-		otm47354
orthoMCL	1	0.900	-	-		OOG6_102032
Panther	1	1.100	-	-	LDO	PTHR10266
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R278
SonicParanoid	1	1.000	-	-		X2430
TreeFam	1	0.960	-	-
	14	13.860