Protein Alignment Klp64D and KIP1

DIOPT Version :9

• Sequence 1: NP_523934.1
• Gene: Klp64D / 38611
• FlyBaseID: FBgn0004380
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_009490.1
• Gene: KIP1 / 852216
• SGDID: S000000159
• Length: 1111
• Species: Saccharomyces cerevisiae
• Alignment Length: 650
• Identity: 199/650 - (30%)
• Similarity: 329/650 - (50%)
• Gaps: 110/650 - (16%)

  Fly    20 NVRVVVRTRPMDKNELSAGALSAISVDKINRAITVMKP-----------NATANEPPKTYYFDNV 73
            |:.|.||.|..:|.|:.         :|.:..|:.:.|           :.:.:...|||.||.|
Yeast    52 NIHVYVRCRSRNKREIE---------EKSSVVISTLGPQGKEIILSNGSHQSYSSSKKTYQFDQV 107

  Fly    74 FDGGSNQMDLYVDTARPIVDKVLEGYNGTILAYGQTGTGKTYTMSGN----PDSPQT-------- 126
            |...|:|..::..||:..:.::|.|||.||.|||||||||||||||:    .|...|
Yeast   108 FGAESDQETVFNATAKNYIKEMLHGYNCTIFAYGQTGTGKTYTMSGDINILGDVQSTDNLLLGEH 172

  Fly   127 KGIIPNAFAHIFGHIAKAKENQKFLVRVSYMEIYNEEVRDLLG---------KDVGKSLEV--KE 180
            .||||.....:|..::..  |:::.|::|::|:|||.::|||.         .|..:.:.:  ..
Yeast   173 AGIIPRVLVDLFKELSSL--NKEYSVKISFLELYNENLKDLLSDSEDDDPAVNDPKRQIRIFDNN 235

  Fly   181 RPDIGVFVKDLSGYVVHNADDLENIMRLGNKNRAVGATKMNQESSRSHAIFSIT---VERSELGE 242
            ..:..:.||.:....:::|.:..|::..|:..|.|.|||.|..|||||.:|:||   ||:.....
Yeast   236 NNNSSIMVKGMQEIFINSAHEGLNLLMQGSLKRKVAATKCNDLSSRSHTVFTITTNIVEQDSKDH 300

  Fly   243 GDVQH-VRMGKLQLVDLAGSERQSKTQASGQRLKEATKINLSLSVLGNVISALVDGKSTHIPYRN 306
            |..:: |::|||.||||||||..:::.|..:|.:||..||.||..||.||:|||| .|.|||||.
Yeast   301 GQNKNFVKIGKLNLVDLAGSENINRSGAENKRAQEAGLINKSLLTLGRVINALVD-HSNHIPYRE 364

  Fly   307 SKLTRLLQDSLGGNSKTVMCATISPADSNYMETISTLRYASRAKNIQNRMHINEE-PKDALLRHF 370
            |||||||||||||.:||.:.||||||..:..||.|||.||:|||:|:|...:|:. .||..|:.:
Yeast   365 SKLTRLLQDSLGGMTKTCIIATISPAKISMEETASTLEYATRAKSIKNTPQVNQSLSKDTCLKDY 429

  Fly   371 QEEIARLRKQLEEGDSLEEEPPSSEEEED--TADDELEAPLEIELESSTIQAVEKKPKKKREKTD 433
            .:||.:||..|:          :|..::.  ...|:|:.     .||::|...|     :..|..
Yeast   430 IQEIEKLRNDLK----------NSRNKQGIFITQDQLDL-----YESNSILIDE-----QNLKIH 474

  Fly   434 AEKEELAKRKNEHQKEIEHAKTEQETLRNKLVSLEGKILVGGENLLEKAQTQELLLEQSIAELEQ 498
            ..:|::.|.|..:..:::        :.|.|.|.:       |.|:...|...:......:|:::
Yeast   475 NLREQIKKFKENYLNQLD--------INNLLQSEK-------EKLIAIIQNFNVDFSNFYSEIQK 524

  Fly   499 -HEKSEEALKQTLQQKATERIDIEERYSTLQDASTGITKKIHRVM---------------QMLMG 547
             |..:.|.:.:.:||:.....:.:::|:|.|:....|::::.:.:               :::.|
Yeast   525 IHHTNLELMNEVIQQRDFSLENSQKQYNTNQNMQLKISQQVLQTLNTLQGSLNNYNSKCSEVIKG 589

  Fly   548 VKSELADQQQEHQREKEGIYENIRSLSREL---ALCELVLNSYVPKE-YQSMINQYTHWNEDIGE 608
            |..||......|:.:.:...:::.:::..|   .:.|||.:.....| :||  :..:|:.:|:.|
Yeast   590 VTEELTRNVNTHKAKHDSTLKSLLNITTNLLMNQMNELVRSISTSLEIFQS--DSTSHYRKDLNE 652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp64D	NP_523934.1	KISc_KIF3	19..352	CDD:276822	147/369 (40%)
		Kinesin	26..352	CDD:278646	144/363 (40%)
		RILP-like	<437..556	CDD:304877	22/134 (16%)
KIP1	NP_009490.1	KISc_BimC_Eg5	50..419	CDD:276815	150/378 (40%)
		235kDa-fam	<423..>948	CDD:130673	47/266 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4221
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940