DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Klp64D and AT3G44050

DIOPT Version :9

Sequence 1:	NP_523934.1	Gene:	Klp64D / 38611	FlyBaseID:	FBgn0004380	Length:	677	Species:	Drosophila melanogaster
Sequence 2:	NP_189991.2	Gene:	AT3G44050 / 823523	AraportID:	AT3G44050	Length:	1263	Species:	Arabidopsis thaliana

Alignment Length:	735	Identity:	229/735 - (31%)
Similarity:	356/735 - (48%)	Gaps:	163/735 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 NVRVVVRTRPMDKNELSA-GALSAISVDKINRAITVMKPNATANEPPKTYYFDNVFDGGSNQMDL 83
            ||:|::||||:..:|:|. |....:..|. .:|||.:      ..|...:.||.|.|...:|..:
plant    93 NVQVIIRTRPLSSSEISVQGNNKCVRQDN-GQAITWI------GNPESRFTFDLVADENVSQEQM 150

  Fly    84 YVDTARPIVDKVLEGYNGTILAYGQTGTGKTYTMSGNPDSPQTK-----GIIPNAFAHIFGHIAK 143
            :.....|:|:.|:.|||..:.||||||:|||:||.|:.:....:     |:.|..|.::|..|.|
plant   151 FKVAGVPMVENVVAGYNSCMFAYGQTGSGKTHTMLGDIEGGTRRHSVNCGMTPRVFEYLFSRIQK 215

  Fly   144 AKENQK-----FLVRVSYMEIYNEEVRDLLGKDVGKSLEVKERPDIGVFVKDLSGYVVHNADDLE 203
            .||.:|     |..|.|::|||||::.|||... ..:|:::|....|:.|::|....|.:|.|:.
plant   216 EKEVRKEEKLHFTCRCSFLEIYNEQILDLLDPS-SYNLQLREDHKKGIHVENLKEIEVSSARDVI 279

  Fly   204 NIMRLGNKNRAVGATKMNQESSRSHAIFSITVERSELGEGDVQHVRMGKLQLVDLAGSERQSKTQ 268
            ..:..|..||.|.||.||:.|||||::|:..:|...:.:| |.|.|..:|.||||||||||..:.
plant   280 QQLMQGAANRKVAATNMNRASSRSHSVFTCIIESKWVSQG-VTHHRFARLNLVDLAGSERQKSSG 343

  Fly   269 ASGQRLKEATKINLSLSVLGNVISALV---DGKSTHIPYRNSKLTRLLQDSLGGNSKTVMCATIS 330
            |.|:||||||.||.|||.||.||..||   :|||.|:|||:||||.||||||||||||::.|.||
plant   344 AEGERLKEATNINKSLSTLGLVIMNLVSVSNGKSVHVPYRDSKLTFLLQDSLGGNSKTIIIANIS 408

  Fly   331 PADSNYMETISTLRYASRAKNIQNRMHINEEPK-DAL-----LRHFQEEIARLR----KQLEEGD 385
            |:.|..:||:|||::|.|||.|:|...:||:.. |.:     ::..::|:.|||    ...::.|
plant   409 PSSSCSLETLSTLKFAQRAKLIKNNAIVNEDASGDVIAMRLQIQQLKKEVTRLRGMGGVDNQDMD 473

  Fly   386 SLEEEPPSS--------------------------------------EEEED------TADDELE 406
            ::....|:|                                      |.|:|      ||::|..
plant   474 TISMGCPASPMSLKWDGFNGSFTPLTTHKRMSKVKDYEVALVGAFRREREKDVALQALTAENEAS 538

  Fly   407 APLE-------------IELESSTIQAVE-----KKPKKKREKTDAEKEELAKRKNEHQKEIEHA 453
            ..||             ::|..|.|::::     |.|         .:..|.|.|.:..||||..
plant   539 MKLEKKREDEIRGLKMMLKLRDSAIKSLQGVTSGKIP---------VEAHLQKEKGDLMKEIEVL 594

  Fly   454 KTEQETLRNKLVSLEGKILVGGENLLEKAQTQELLLEQSIAELE-QHEKSEEALK----QTLQQK 513
            :.:.:  ||:.|:              |..|:.|.|::.|..|: |.|:.|..:.    |.||.|
plant   595 RAQVD--RNQEVT--------------KFATENLRLKEEIRRLKSQGEEGERDILNQQIQALQAK 643

  Fly   514 ATERIDIEERYSTLQDASTGITKKIHRVMQM-----------LMGVKSE---LADQQQEHQREKE 564
            ..|.:|    :..:.::.:.:.|:...:..|           |..::.|   |..|..:::.|.|
plant   644 LLEALD----WKLMHESDSSMVKEDGNISNMFCSNQNQESKKLSSIQDENEFLRMQAIQNRAEME 704

  Fly   565 GIYENIR-SLSRELALCELVLNSYVPKEYQSMINQYTHWNEDIGEWQLK-------CVAYTGNNM 621
            .:.:::. ||..:..|.:||.|  :..|.:..|.......:| .:.::|       ||:
plant   705 SLQKSLSFSLDEKERLQKLVDN--LSNELEGKIRSSGMVGDD-DQMEVKTMVQAIACVS------ 760

  Fly   622 RKHISAHKTS---GKEPDFL 638
            ::...||:|:   .||.|.|
plant   761 QREAEAHETAIKLSKENDDL 780

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Klp64D	NP_523934.1	KISc_KIF3	19..352	CDD:276822	152/345 (44%)
		Kinesin	26..352	CDD:278646	149/339 (44%)
		RILP-like	<437..556	CDD:304877	30/137 (22%)
AT3G44050	NP_189991.2	Motor_domain	92..439	CDD:354959	155/354 (44%)
AT3G44050	NP_189991.2	Smc	521..1260	CDD:224117	65/298 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4280
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.770