Protein Alignment Klp64D and AT3G10180

DIOPT Version :10

• Sequence 1: NP_523934.1
• Gene: Klp64D / 38611
• FlyBaseID: FBgn0004380
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_187629.3
• Gene: AT3G10180 / 820180
• AraportID: AT3G10180
• Length: 1273
• Species: Arabidopsis thaliana
• Alignment Length: 675
• Identity: 207/675 - (30%)
• Similarity: 325/675 - (48%)
• Gaps: 129/675 - (19%)

  Fly    18 IENVRVVVRTRPMDKNELSAGALSAISVDKINRAITVMKPNATANEPPKTYYFDNVFDGGSNQMD 82
            :|.:.|.||.||:...:....... ||.|      ::..||.::    ..:.||.:|......:.
plant     1 MERIHVSVRARPLSSEDAKTSPWK-ISSD------SIFMPNHSS----LAFEFDRIFREDCKTVQ 54

  Fly    83 LYVDTARPIVDKVLEGYNGTILAYGQTGTGKTYTMSGNPDSPQTKGIIPNAFAHIFGHIAKAKEN 147
            :|....:.||...:.|:|||:.|||||.:|||:||.|:|..|   |:||.|...:|..|.: ..:
plant    55 VYEARTKEIVSAAVRGFNGTVFAYGQTNSGKTHTMRGSPIEP---GVIPLAVHDLFDTIYQ-DAS 115

  Fly   148 QKFLVRVSYMEIYNEEVRDLLGKDVGKSLEVKERPDIGVFVKDLSGYVVHNADDLENIMRLGNKN 212
            ::||:|:||:|||||::.|||..: .:.|::.|..:.|:||..|...:|.:...:..:|..|..:
plant   116 REFLLRMSYLEIYNEDINDLLAPE-HRKLQIHENLEKGIFVAGLREEIVASPQQVLEMMEFGESH 179

  Fly   213 RAVGATKMNQESSRSHAIFSITVE-RSELGEGDVQH----VRMGKLQLVDLAGSERQSKTQASGQ 272
            |.:|.|.||..|||||.||.:.:| |.::.:..|.:    ||:..|.|||||||||.:||.|.|.
plant   180 RHIGETNMNLYSSRSHTIFRMIIESRQKMQDEGVGNSCDAVRVSVLNLVDLAGSERAAKTGAEGV 244

  Fly   273 RLKEATKINLSLSVLGNVISALVDGKST---HIPYRNSKLTRLLQDSLGGNSKTVMCATISPADS 334
            ||||.:.||.||..||.||..|.:|..|   |:|||:|||||:||.:||||:.|.:...|:.|..
plant   245 RLKEGSHINKSLMTLGTVIKKLSEGVETQGGHVPYRDSKLTRILQPALGGNANTAIICNITLAPI 309

  Fly   335 NYMETISTLRYASRAKNIQNRMHINEEPKD-ALLRHFQEEIARLRKQLEEGDSLEEEPPSSEEE- 397
            :..||.|:|::||||..:.|..|:||...| |||:..::||..||.:|:...|     ..||||
plant   310 HADETKSSLQFASRALRVTNCAHVNEILTDAALLKRQKKEIEELRSKLKTSHS-----DHSEEEI 369

  Fly   398 ----EDTADDELEAP-LEIELESSTIQAVEKKPKKKREKTDAEKEELAKRKN----------EHQ 447
                ......|||.. :.:|||.      |||.:.:||:  ..:|:..|.||          :.:
plant   370 LNLRNTLLKSELERERIALELEE------EKKAQAQRER--VLQEQAKKIKNLSSMVLLSNRDEK 426

  Fly   448 KEIEHAKTEQ--------ETLRNKLVSLEGKILVGGENLLEKAQTQE-----LLLEQSIAE--LE 497
            :|.:|.|..:        :..|:.....:..:|..|.: ||.|:::.     |...:.:.|  ..
plant   427 REQDHFKKGKRRDTWCIGKLSRDSTSEDQSNVLSRGSS-LESARSERETGPLLPFSELVNEPLYN 490

  Fly   498 QHEKSEEALKQTLQQKATERIDIEERYSTLQDASTGITKKIHRVMQMLMGVKSELADQQQEHQRE 562
            .:|:.|::::.||:.            |.|.|...            |:.|.|          |:
plant   491 INEEDEDSIEGTLED------------SVLPDPCA------------LVNVTS----------RK 521

  Fly   563 KEGI-YENIRSLSRELALCELVLNSYVPKEYQSMINQYTHWNEDIGEWQLKCV-------AYTGN 619
            |..| .:|...:..||        ..:.:||::::.|| .....|.|.|::|:       ..:|:
plant   522 KPSIKQKNPVVVENEL--------DRIQREYEALLLQY-ETERIISEIQIECLKVKLGEDGLSGD 577

  Fly   620 NMRK--------HISAHKTSGKEPD 636
            ...|        |...|..:.::|:
plant   578 AKCKQSEVVGNVHCEEHVVNLRDPE 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp64D	NP_523934.1	KISc_KIF3	19..352	CDD:276822	134/340 (39%)
		Smc	<433..>578	CDD:440809	30/170 (18%)
AT3G10180	NP_187629.3	KISc_CENP_E	4..327	CDD:276825	133/338 (39%)
		sbcc	<335..904	CDD:129705	70/325 (22%)
		SMC_prok_B	644..>1268	CDD:274008