Protein Alignment Klp64D and STARD9

DIOPT Version :10

• Sequence 1: NP_523934.1
• Gene: Klp64D / 38611
• FlyBaseID: FBgn0004380
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: XP_011520133.1
• Gene: STARD9 / 57519
• HGNCID: 19162
• Length: 4705
• Species: Homo sapiens
• Alignment Length: 549
• Identity: 180/549 - (32%)
• Similarity: 259/549 - (47%)
• Gaps: 110/549 - (20%)

  Fly    20 NVRVVVRTRPMDKNELSAGALSAISVD----KINRAITVMKPNATANEPPKT--------YYFDN 72
            ||:|.||.||:.|.|...|....:.||    ||.......:|:...:...|.        |:..|
Human     3 NVQVAVRVRPLSKRETKEGGRIIVEVDGKVAKIRNLKVDNRPDGFGDSREKVMAFGFDYCYWSVN 67

  Fly    73 VFDGGSNQMD-LYVDTARPIVDKVLEGYNGTILAYGQTGTGKTYTMSGNPDSPQTKGIIPNAFAH 136
            ..|......| ::.|....::..|.:|||..:.||||||:||||||.|.|.|   .|:.|.....
Human    68 PEDPQYASQDVVFQDLGMEVLSGVAKGYNICLFAYGQTGSGKTYTMLGTPAS---VGLTPRICEG 129

  Fly   137 IFGHIAKAKE----NQKFLVRVSYMEIYNEEVRDLL---GKDVGKSLEVKERPDIGVFVKDLSGY 194
            :|   .:.|:    .....::||::|||||.|||||   |:....:|.|:|.|::|.:|:.||.:
Human   130 LF---VREKDCASLPSSCRIKVSFLEIYNERVRDLLKQSGQKKSYTLRVREHPEMGPYVQGLSQH 191

  Fly   195 VVHNADDLENIMRLGNKNRAVGATKMNQESSRSHAIFSITVERSELGEGDVQHVRMGKLQLVDLA 259
            ||.|...:..::..|..||...||.:::.||||||||:|...::.| |.::......|:.|||||
Human   192 VVTNYKQVIQLLEEGIANRITAATHVHEASSRSHAIFTIHYTQAIL-ENNLPSEMASKINLVDLA 255

  Fly   260 GSERQSKTQASGQRLKEATKINLSLSVLGNVISALVDG--------------------------- 297
            ||||...:... .|:.|...||.||..||.|||.|...
Human   256 GSERADPSYCK-DRIAEGANINKSLVTLGIVISTLAQNSQVFSSCQSLNSSVSNGGDSGILSSPS 319

  Fly   298 ----------KSTHIPYRNSKLTRLLQDSLGGNSKTVMCATISPADSNYMETISTLRYASRAKNI 352
                      :.::||||:|.||.||:|||||||||:|.||:|||.::|.||:|||||||.||||
Human   320 GTSSGGAPSRRQSYIPYRDSVLTWLLKDSLGGNSKTIMVATVSPAHTSYSETMSTLRYASSAKNI 384

  Fly   353 QNRMHINEEPKDALLRHFQEEIARLRKQLEEGDSLEEEPPSSEEEEDTADDELEAPLEIELESST 417
            .|:..:||:....|:|..:|||.||:..|.   |.|....||..:|:..    |..|:.||
Human   385 INKPRVNEDANLKLIRELREEIERLKALLL---SFELRNFSSLSDENLK----ELVLQNEL---- 438

  Fly   418 IQAVEKKPKKKREKTDAEKEELAKRKNEHQKEIEHAKTEQETLR---------NKLVSLEGKILV 473
                         |.|...::..::.|:.|..:||...:....|         ..|::||..:|.
Human   439 -------------KIDQLTKDWTQKWNDWQALMEHYSVDINRRRAGVVIDSSLPHLMALEDDVLS 490

  Fly   474 GGENL------------LEKAQTQELLLE 490
            .|..|            ::..|.|:::|:
Human   491 TGVVLYHLKEGTTKIGRIDSDQEQDIVLQ 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp64D	NP_523934.1	KISc_KIF3	19..352	CDD:276822	142/388 (37%)
		Smc	<433..>578	CDD:440809	15/79 (19%)
STARD9	XP_011520133.1	KISc_KIF1A_KIF1B	2..391	CDD:276816	145/395 (37%)
		Kinesin_assoc	390..501	CDD:465047	32/134 (24%)
		FHA_KIF16A_STARD9	471..589	CDD:438783	9/49 (18%)
		COG4913	<580..>786	CDD:443941
		START_STARD9-like	4496..4705	CDD:176883