Protein Alignment Klp64D and kif21b

DIOPT Version :10

• Sequence 1: NP_523934.1
• Gene: Klp64D / 38611
• FlyBaseID: FBgn0004380
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: XP_073772347.1
• Gene: kif21b / 570502
• ZFINID: ZDB-GENE-130530-537
• Length: 1669
• Species: Danio rerio
• Alignment Length: 789
• Identity: 221/789 - (28%)
• Similarity: 342/789 - (43%)
• Gaps: 203/789 - (25%)

  Fly    20 NVRVVVRTRPMDKNELSAGALSAISVDKINRAITVMKPNATANEP------PKTYYFDNVFDGGS 78
            :|:|.:|.||....|...|.....||              |..||      .|.:.:|.|||..:
Zfish     8 SVKVSLRIRPQMAKEKIEGCHICTSV--------------TPGEPQVLLGKDKAFTYDFVFDLDA 58

  Fly    79 NQMDLYVDTARPIVDKVLEGYNGTILAYGQTGTGKTYTMSGNPD---SPQTKGIIPNAFAHIFGH 140
            :|..:|......:::...||||.|:.||||||:||||||....|   |...:||||.|...:|..
Zfish    59 HQQQIYSACVHKLIEGCFEGYNATVFAYGQTGSGKTYTMGTGFDVSVSEDEQGIIPRAVHQLFQG 123

  Fly   141 IAKAK-ENQK-------FLVRVSYMEIYNEEVRDLL-------GKDVGKSLEVKERPDIGVFVKD 190
            |.|.: |.|.       |.|...::|:||||:.||.       .:....::::.|....|::...
Zfish   124 IQKRRLEAQSADIPPPDFKVSAQFLELYNEEILDLFDSTRDPEARGRKSNIKIHEDGSGGIYTTG 188

  Fly   191 LSGYVVHNADDLENIMRLGNKNRAVGATKMNQESSRSHAIFSI------TVERSELGEGDVQHVR 249
            ::..:|.:.|:|...::||..:|...:|:||.:||||||||:|      ...:.:|..|::..|.
Zfish   189 VTSRLVSSEDELLQCLKLGALSRTTASTQMNAQSSRSHAIFTIHLCQMRVCPQPQLVNGELNGVS 253

  Fly   250 MG------------KLQLVDLAGSERQSKTQASGQRLKEATKINLSLSVLGNVISALVD--GKST 300
            .|            |...||||||||..:|.|:|:|.:|...||..|..||||||||.|  .::.
Zfish   254 DGSMSQSEYETLSAKFHFVDLAGSERLKRTGATGERAREGISINCGLLALGNVISALGDQSKRAG 318

  Fly   301 HIPYRNSKLTRLLQDSLGGNSKTVMCATISPADSNYMETISTLRYASRAKNIQNRMHINEEPKDA 365
            |:|||:|||||||||||||||:|||.|.:||:|.::|||::||:||:||:||:|::.:|::....
Zfish   319 HVPYRDSKLTRLLQDSLGGNSRTVMIACVSPSDRDFMETLNTLKYANRARNIKNKVIVNQDKTSQ 383

  Fly   366 LLRHFQEEIARLRKQL-----------EEG----DSLEEEPPSSEEEEDTADDELEAPLEI--EL 413
            .:...:.|||||:.::           :||    ..|.:|....:.|.||....::|..|.  .|
Zfish   384 QISALRAEIARLQMEIMEYKAGKRVACDEGSEGFSDLFQENSMLQRENDTLRMRVKAMQETIDHL 448

  Fly   414 ESSTIQAVEKKPKKKREKTDAEKEELAKRKNEHQKEIEHAKTE-------QETLRNKL------- 464
            .:...|.:.........||....||:......:.:|||..:::       .|:||..|
Zfish   449 NTRVTQLLTNGVNLLLTKTGETNEEIGNLIQNYIREIEELRSKLLESEAMNESLRRSLSRLSSRS 513

  Fly   465 -----------------VSLEGKIL-------VGGENLLEKAQTQE---------LLLEQSIAEL 496
                             ||:|.::.       :..|.|.:|.:.|.         |.....:...
Zfish   514 VYPSSHPSAPSIGSSPSVSMEAEMTDVIRQAKLDVERLKKKERNQRRKRPEKEKGLKKRAKLHPE 578

  Fly   497 EQHEKSEEALKQT-----------------------LQQ------------------KATERIDI 520
            |..||||..|.:.                       ||:                  :..|..|.
Zfish   579 ESGEKSENGLNRANEERRENGDGDSDNEPEEDGMYPLQEDDHGESGCDEEEEEEEETREEEEFDS 643

  Fly   521 EERYSTLQDASTGITKKIHRVMQML-----MGVKSELADQQQEHQR----------EKEGIYEN- 569
            :|   :|.|:.:...:|::....:.     :.:|..|.|:.:..||          ||..:.:|
Zfish   644 DE---SLVDSDSDTDEKVNLQADLADLTCEIEIKQRLIDELENSQRRLLTLKSQYEEKLILLQNK 705

  Fly   570 IR--SLSRELALCELV-LNSY-------VPKEYQSMINQYTHWNEDIGEWQLKCVAYTGNNMRKH 624
            ||  .|.|:..|..|: :.:|       |..||:..:.:   .|.|:    ||..|    ..::|
Zfish   706 IRDTQLERDRVLHNLMSMENYTEEKASKVKSEYEKRLKE---MNRDL----LKLQA----AQKEH 759

  Fly   625 ISAHKTSGK 633
            ....|..|:
Zfish   760 ARLLKNQGR 768

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp64D	NP_523934.1	KISc_KIF3	19..352	CDD:276822	142/375 (38%)
		Smc	<433..>578	CDD:440809	43/250 (17%)
kif21b	XP_073772347.1	None