Protein Alignment Klp64D and kif5aa

DIOPT Version :10

• Sequence 1: NP_523934.1
• Gene: Klp64D / 38611
• FlyBaseID: FBgn0004380
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_001186705.1
• Gene: kif5aa / 566086
• ZFINID: ZDB-GENE-070912-141
• Length: 1033
• Species: Danio rerio
• Alignment Length: 762
• Identity: 237/762 - (31%)
• Similarity: 353/762 - (46%)
• Gaps: 149/762 - (19%)

  Fly    20 NVRVVVRTRPMDKNELSAGALSAISVDKINRAITVMKPNATANEPPKTYYFDNVFDGGSNQMDLY 84
            |::|:.|.||:::.|:..|       ||.   :...:.:.|.....|:|.||.||...:.|..:|
Zfish     9 NIKVLCRFRPLNQAEILRG-------DKF---LPTFQGDDTVIIGGKSYAFDRVFPTNTTQEQVY 63

  Fly    85 VDTARPIVDKVLEGYNGTILAYGQTGTGKTYTMSGNPDSPQTKGIIPNAFAHIFGHIAKAKENQK 149
            ...|:.||..||.||||||.|||||.:|||:||.||...||..||||.....||.||....||.:
Zfish    64 NTCAKQIVKDVLGGYNGTIFAYGQTSSGKTHTMEGNLHDPQQMGIIPRIAEDIFNHIFSMDENLE 128

  Fly   150 FLVRVSYMEIYNEEVRDLLGKDVGK-SLEVKERPDIGVFVKDLSGYVVHNADDLENIMRLGNKNR 213
            |.::|||.|||.|::||||  ||.| :|.|.|..:...:||..:...|.:.:::.:::..|..||
Zfish   129 FHIKVSYFEIYMEKIRDLL--DVTKTNLSVHEDKNRVPYVKGCTERFVSSPEEVMDVIDEGKSNR 191

  Fly   214 AVGATKMNQESSRSHAIFSITVERSELGEGDVQHVRMGKLQLVDLAGSERQSKTQASGQRLKEAT 278
            .|..|.||:.|||||:||.|.:::..:   :.:....|||.||||||||:.|||.|:|..|.||.
Zfish   192 HVAVTNMNEHSSRSHSIFLINIKQEHV---ETEQKLCGKLYLVDLAGSEKVSKTGAAGAVLDEAK 253

  Fly   279 KINLSLSVLGNVISALVDGKSTHIPYRNSKLTRLLQDSLGGNSKTVMCATISPADSNYMETISTL 343
            .||.|||.||||||||.:|..:|:|||:||:||:||||||||.:|.|....||:..|..||.|||
Zfish   254 NINKSLSALGNVISALAEGTKSHVPYRDSKMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTL 318

  Fly   344 RYASRAKNIQNRMHIN--------------EEPKDALLRHFQEEIARLRKQLEEGDSLEEEPPSS 394
            .:..|||.|:|...||              |:.|:..||   :.:.||..:|....:.|:.|.:.
Zfish   319 MFGQRAKTIKNTASINLELTAEQWKRKYEKEKEKNKSLR---DSMQRLELELRRWRNGEKVPETE 380

  Fly   395 E----------EEEDTADDE--LEAPLEIELESSTIQAVEKKPKKKREKTDAEKEELAKRKNEHQ 447
            :          .||.:.|:|  .|...|.|.:|.|...|.:..:::|:|.:.|..:|.::.::..
Zfish   381 QTDADVVKLDVSEETSLDNEKSCERQRERERDSDTSSIVVRISEEERQKYEEEIRKLYRQLDDKD 445

  Fly   448 KEIEHAKTEQETLRNKLVSLE-----------------GKILVGGENLLEKAQTQELL------- 488
            .||.......|.|:.:::..:                 |::....|:  .||:.:|:|
Zfish   446 DEINLQCQLVEKLKEQILDQDELLASTRGDSDKVQTELGRLQTESES--AKAEVREVLQALEELA 508

  Fly   489 --LEQSIAELEQHEKSEEALKQTLQQKATERIDIEERYSTLQDASTGITKKIHRVMQMLM----- 546
              .:|...|:|:.....:.|.:.|..|....:::|...:.:|:.|:...|:|..|:..||
Zfish   509 VNYDQKSQEVEEKSLHNKQLAEQLSHKMANLMELEAELAQMQEVSSQQRKRIADVLNGLMKDLSE 573

  Fly   547 --------------------------------GVKSE----------LADQQQEHQREKEGIYEN 569
                                            .:|||          |.:.|.|..|:.|
Zfish   574 FSSIVGNGELKLPVEISGAIEEEFTVARLYISKIKSEVKSMVKRCRQLENMQLECHRKME----- 633

  Fly   570 IRSLSRELALCELVLNSYVPK-----EYQSMINQYTHWNEDIGEWQLKCVAYTGNNMRKHISAHK 629
              ..||||:.|:|:::.:..|     ||...:.|.....||..: .|....||..|...|: |..
Zfish   634 --ETSRELSSCQLLISQHEAKIRSLTEYMQNVEQKKRQLEDNYD-ALSEELYTLQNSESHV-AEL 694

  Fly   630 TSGKEPDFLDLSHVYLSYNTDGVSNPMRSKSARPRTSGVPRPTTARR 676
            ..|::.|          ...||     :..:.||......|.|...|
Zfish   695 DGGEKAD----------READG-----KKAAVRPALHAESRQTQLSR 726

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp64D	NP_523934.1	KISc_KIF3	19..352	CDD:276822	151/332 (45%)
		Smc	<433..>578	CDD:440809	37/217 (17%)
kif5aa	NP_001186705.1	KISc_KHC_KIF5	7..327	CDD:276820	151/332 (45%)
		SMC_prok_B	<334..614	CDD:274008	51/284 (18%)
		SMC_N	478..>809	CDD:481474	55/275 (20%)
		Khc_CBD_cc	842..911	CDD:467880