Protein Alignment Klp64D and kif14

DIOPT Version :10

• Sequence 1: NP_523934.1
• Gene: Klp64D / 38611
• FlyBaseID: FBgn0004380
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: XP_005170522.2
• Gene: kif14 / 562052
• ZFINID: ZDB-GENE-030131-5759
• Length: 1506
• Species: Danio rerio
• Alignment Length: 793
• Identity: 230/793 - (29%)
• Similarity: 346/793 - (43%)
• Gaps: 190/793 - (23%)

  Fly    11 TAQLDDEIENVRVVVRTRPMDKNELSAGALSAISVDKINRAITVMKPNATANEPPKTYYFD---- 71
            |.:|..|...|.|.||.||....|.:..|...|.::  |:...|..|: |......|:.|.
Zfish   226 TQELKMENSAVTVAVRVRPFSSREKNEKACQVIFME--NQDTLVQHPD-TKQTHKFTFDFSFCSI 287

  Fly    72 NVFDGG-SNQMDLYVDTARPIVDKVLEGYNGTILAYGQTGTGKTYTMSGNPDSPQTKGIIPNAFA 135
            |..|.. |:|..:|...|||::::..:|:|..:.||||||:||:|||.|   ..:..|:||....
Zfish   288 NEADASFSSQQLIYEKLARPLLERAFDGFNTCLFAYGQTGSGKSYTMMG---FGEETGVIPRFCE 349

  Fly   136 HIFGHIAKAKENQKFL-VRVSYMEIYNEEVRDLL-GKDVGKS----LEVKERPDIGVFVKDLSGY 194
            .:|..:|:::..:... :.:||.|:|||::.||| .||....    |.|:|.|..|.:|.|||..
Zfish   350 ELFSRLARSETKEMSCHLEMSYFEVYNEKIHDLLVAKDEQNQKKMPLRVREHPVYGPYVADLSTN 414

  Fly   195 VVHNADDLENIMRLGNKNRAVGATKMNQESSRSHAIFSITVERSE---LGEGDVQHVRMGKLQLV 256
            ||.:..|::..:.||||.||..||.||.:|||||::|::.:.:::   :.|.:..|....::.||
Zfish   415 VVSSYSDIKTWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEEEEHDHCITSRINLV 479

  Fly   257 DLAGSERQSKTQASGQRLKEATKINLSLSVLGNVISALVD----GKSTHIPYRNSKLTRLLQDSL 317
            |||||||.:..|.||.||:|...||.||..||.|||:|.:    .|....|||.|.||.||::||
Zfish   480 DLAGSERCTSAQTSGDRLREGASINKSLLTLGKVISSLSEQSQSRKKVFTPYRESVLTWLLKESL 544

  Fly   318 GGNSKTVMCATISPADSNYMETISTLRYASRAKNIQNRMHINEEPKDALLRH------------- 369
            ||||||.|.||:|||.||..|::||||||.:|:.|.|...:||:....|:|.
Zfish   545 GGNSKTAMIATLSPAASNMEESLSTLRYAQQARMIINIAKVNEDTNAKLIRDLKAEVEKLRAAQM 609

  Fly   370 ------------FQEEIARL------------------RKQLEEGD------------------- 385
                        ||:|||.|                  :::|||.:
Zfish   610 SSQGVEPEKMRLFQQEIAALKNKLCQQEHEMAEAHRTWKEKLEEAERRKREEAKELQRAGVTFKV 674

  Fly   386 --------SLEEEPPSSE------EEEDTADDEL--EAPLEIELESSTIQ-------------AV 421
                    :|.|:|..||      :|..|...:|  |:..:|:|..:.|.             ::
Zfish   675 DNRLPNLVNLNEDPQLSEMLLYMIKEGQTKVGKLKSESAHDIQLSGALIADQHCVISSVKGTVSI 739

  Fly   422 EKKPKKK----------------------------REKTDAEKEELAKR-----KNEHQKEIEHA 453
            :..|..|                            |....||.:. .||     ..:..|:.|.|
Zfish   740 KPMPNAKTFVNGHLVSECTVLHHGDRVILGGDHYFRFNHPAEVQS-GKRASCWSSGDGHKDFEFA 803

  Fly   454 KTE-------------QET-LRNKLVSLEGKILVGGENLLEKAQTQELLLEQSIAELEQH--EKS 502
            |.|             ||. |:.|...::| |.|..|...::...|:.|.|..|..||:.  |:|
Zfish   804 KNELLSAQRAQLEAEIQEARLKAKEEMMQG-IQVAKEMAQKELSEQKSLYEIKIRALERELKEES 867

  Fly   503 EEALKQTL-QQKATERIDIEERYSTLQDASTGITKKI----HRVMQMLMGVKSELADQQQEHQRE 562
            |...:|.| :|:|..:|:      .||...|.:.|::    .|:.......:..:||....|.:.
Zfish   868 ERKREQELHKQRAASQIE------QLQSVKTLLEKEVSSHKRRLQMEAQATRQAMADHDVRHAKI 926

  Fly   563 KEGIYENIRSLSRELALCELVLNSYVPKEYQSMINQYTHWNEDIGEWQLKCVAYTGN----NMRK 623
            ...:....|.::.:||..|:.....|.:..:..|.|   |:    ..:|..:....|    .:||
Zfish   927 VAALEAEKRKIAEDLAQIEMKRALKVTQTPKMAIPQ---WD----AMKLSLMIEEANKISGKLRK 984

  Fly   624 H--ISAHKTSGKE 634
            |  .|.|:.:.||
Zfish   985 HTVFSRHEAADKE 997

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp64D	NP_523934.1	KISc_KIF3	19..352	CDD:276822	141/350 (40%)
		Smc	<433..>578	CDD:440809	40/170 (24%)
kif14	XP_005170522.2	None