Protein Alignment Klp64D and Kif9

DIOPT Version :10

• Sequence 1: NP_523934.1
• Gene: Klp64D / 38611
• FlyBaseID: FBgn0004380
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: XP_006244056.1
• Gene: Kif9 / 501059
• RGDID: 1565187
• Length: 860
• Species: Rattus norvegicus
• Alignment Length: 697
• Identity: 205/697 - (29%)
• Similarity: 317/697 - (45%)
• Gaps: 143/697 - (20%)

  Fly    19 ENVRVVVRTRPMDKNELSAGALSAISVDKINRAITV-----MKPNATANEPPK-TYYFDNVFDGG 77
            :.|:..||.:|.|.     .|...|...:.|::|.:     .:..|..|:... ::..|.|....
  Rat    75 KKVQAFVRVKPTDD-----FAHEMIKYGEDNKSIDIHLKKDTRRGAVNNQQTDWSFKLDGVLHDA 134

  Fly    78 SNQMDLYVDTARPIVDKVLEGYNGTILAYGQTGTGKTYTMSGNPDSPQTKGIIPNAFAHIFGHIA 142
            |..: :|...|:..|.:.|:||||||:.|||||.||||||:|..::.:.:||:|.|...:| .:.
  Rat   135 SQDL-VYETVAKDAVSQALDGYNGTIMCYGQTGAGKTYTMTGATENYKHRGILPRALQQVF-RMI 197

  Fly   143 KAKENQKFLVRVSYMEIYNEEVRDLLG--KDVGKS---LEVKERPDIGVFVKDLSGYVVHNADDL 202
            :.:......|||||:|||||.:.|||.  ..||.|   :.:.|.|. |||:|.||.::....:|.
  Rat   198 EERPTHAITVRVSYLEIYNENLFDLLSTLPYVGPSVTPMTIVENPQ-GVFIKGLSVHLTSQEEDA 261

  Fly   203 ENIMRLGNKNRAVGATKMNQESSRSHAIFSITVERSELGEGDVQHVRMGKLQLVDLAGSERQSKT 267
            .:::..|..||.:.:..||:.|||||.||:|.:|.......|.::: ..|:.|||||||||.|||
  Rat   262 FSLLFEGETNRIIASHTMNKNSSRSHCIFTIYMEAHSRTLSDEKYI-TSKINLVDLAGSERLSKT 325

  Fly   268 QASGQRLKEATKINLSLSVLGNVISALVDGKSTHIPYRNSKLTRLLQDSLGGNSKTVMCATISPA 332
            .:.|:.|||||.||.|||.|...|.||.|....|||:|.||||..|:||||||...|:...|...
  Rat   326 GSEGRVLKEATYINKSLSFLEQAIIALGDQNRDHIPFRQSKLTHALKDSLGGNCNMVLVTNIYGE 390

  Fly   333 DSNYMETISTLRYASRAKNIQNRMHINEE-PKDALLRHFQEEIARLRKQLEEGDSLEEE-----P 391
            .:...||:|:||:|||.|.:.....|||: ..:.::::.::|:|.|:::|...|||...     .
  Rat   391 AAQLDETLSSLRFASRMKLVTTEPAINEKYDAERMVKNLEKELALLKQELAIHDSLSNRTLVNYD 455

  Fly   392 PSSEEE------------EDTADD-------------------------ELEAPLEIEL------ 413
            |..|.:            |.|.|:                         |:|:.|..:.
  Rat   456 PMDEIQIAEINSQVRRYLEGTLDEIDIINLRQIQEVFNQFRVVLSQQEQEVESALRRKYTLIDKN 520

  Fly   414 ESSTIQAVEK----------------------------KP--KKKREKTDAEKEELAKRKNEHQK 448
            :.:.|.||:|                            ||  |.|.:||..::...:.||.....
  Rat   521 DFAAISAVQKAGLMDVEGHLVGEPDGQSFGLGVAPFSVKPGKKSKTKKTTKDQFSSSARKEGASS 585

  Fly   449 EIEHAKTEQETL-RNKLV--SLEGKILVGGENLLEKAQTQELLLEQSIAELEQHEKSEE------ 504
            .:.....:..:: :.:|:  |.||.:   .:.|:.:.:|      .||..|......||
  Rat   586 PVSGKDFDMTSISKTQLIPSSKEGDL---KDMLVRERET------SSIEPLPSDSPKEESRALRP 641

  Fly   505 --------ALKQTLQQKATE--RIDIEERYSTLQDASTGITKKIHRVMQMLMGVKSEL-----AD 554
                    |.::...::.:|  || .:|..|.|.:..    |:.....|.:..:|.|:     |.
  Rat   642 STPPSKPVAFEEFKNERGSEINRI-FKENKSILNERK----KRASETTQRINAIKQEIDVTKEAL 701

  Fly   555 QQQEHQREKEGIYEN--IRSLSRELALCELVLNSYVPKEYQSMINQY 599
            ..|:..|||:|.|||  :..:..|..|..|.|.. :.|:|:   |:|
  Rat   702 NFQKSLREKQGEYENKGLMIIDEEEFLLILKLKD-LKKQYR---NEY 744

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp64D	NP_523934.1	KISc_KIF3	19..352	CDD:276822	136/343 (40%)
		Smc	<433..>578	CDD:440809	34/170 (20%)
Kif9	XP_006244056.1	KISc_KIF9_like	76..408	CDD:276826	135/340 (40%)