Protein Alignment Klp64D and LOC4576148

DIOPT Version :10

• Sequence 1: NP_523934.1
• Gene: Klp64D / 38611
• FlyBaseID: FBgn0004380
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: XP_061512564.1
• Gene: LOC4576148 / 4576148
• VectorBaseID: AGAMI1_001728
• Length: 1254
• Species: Anopheles gambiae
• Alignment Length: 719
• Identity: 214/719 - (29%)
• Similarity: 322/719 - (44%)
• Gaps: 131/719 - (18%)

  Fly     2 PQEEANAGTTAQLDDEIENVRVVVRTRPMDKNELSAGALSAISVDKINRAITVMKPNAT------ 60
            |:|...|...|.:... |.|:|.||.|||.::|.:.|..:.:.         ...|.|.
Mosquito    14 PREPTKAPGAAAMPGP-ECVKVAVRIRPMSQSEQARGCQTVVE---------QAAPGAPQLLVCG 68

  Fly    61 ANEPPKTYYFDNVFDGGSNQMDLYVDTARPIVDKVLEGYNGTILAYGQTGTGKTYTM----SGNP 121
            ...|...:.:..||...:.|..||.....|::.|:..|||.||||||||.:|||:||    :|..
Mosquito    69 GRTPSDVFSYSYVFPPSTVQSQLYEVAVSPMLHKLFAGYNATILAYGQTSSGKTFTMGTHFAGEV 133

  Fly   122 DSPQTKGIIPNAFAHIF----GHIAKAKENQKFLVRVSYMEIYNEEVRDLLG-KDVG---KSLEV 178
            ||  :.|:||.|...||    ...|:...:....|..||:|:|.::|.|||. |..|   :.:::
Mosquito   134 DS--SVGVIPRAINDIFRLMADGTAEVTAHVDTRVTCSYIEVYQDQVFDLLAEKPAGTERQPVDI 196

  Fly   179 KERPDIGVFVKDLSGYVVHNADDLENIMRLGNKNRAVGATKMNQESSRSHAIFSITVERSELGEG 243
            :|.....:.::.|:...........:.:..|:..|.|.||.||..||||||||::|:..:  ...
Mosquito   197 REAVGGDIILQGLTEVAAGGVQSAFDCLARGSLGRVVRATAMNNVSSRSHAIFTLTLHHT--ARD 259

  Fly   244 DVQHVRMGKLQLVDLAGSERQSKTQASGQRLKEATKINLSLSVLGNVISALVDGKST------HI 302
            |...|...|..|||||||||..||..:|.|.||..:||..|..|||||:||  |.|.      ||
Mosquito   260 DPAVVTRSKFHLVDLAGSERSKKTDTTGDRFKEGVQINKCLLALGNVITAL--GSSAGAAGKMHI 322

  Fly   303 PYRNSKLTRLLQDSLGGNSKTVMCATISPADSNYMETISTLRYASRAKNIQNRMHINEEPKDALL 367
            |||:|||||||||||||||.|:|.|.:||||.|..||.||||||:|...|:|:..:|::|:.|.:
Mosquito   323 PYRSSKLTRLLQDSLGGNSYTLMIACVSPADYNLSETYSTLRYANRVCKIKNKPIVNQDPQQARI 387

  Fly   368 RHFQEEIARLRKQLEEGDSLEEEPPSSEEEEDT--ADDELEAPLEIEL-ESSTIQAVEKKPKKKR 429
            :..:..:..||.::....|..|..|.:.:::.|  ....:.:||...| |:..:::.........
Mosquito   388 KQLEAIVQDLRVEVMMLKSGREGCPPTTDKDGTFRVPQPVHSPLVRGLTETQLLRSPRSSEAGSA 452

  Fly   430 EKTDAEKEELAKRKNEHQKEIEHAKTEQETLRNKLVSLEGKILVGGENLLEKAQTQELLLEQSIA 494
            ....|..::|.:.....||:::....|                      ||..:.:.:|.|:.:.
Mosquito   453 SDPSAGYQKLQEANRCLQKQLQATMHE----------------------LEVHEERSMLAEKLLE 495

  Fly   495 ELEQ-----HEKSEEALKQTLQQKATERIDIEERYSTLQDASTGITKKIHRVMQML---MGVKSE 551
            ::||     .:..|:.|:|.|.:..|...|  |.|| |...|......:.|:::..   .||...
Mosquito   496 DIEQLLGREAQPGEDGLRQELARLLTAHQD--EVYS-LGSLSAAYGPPLSRMIRPSTAGAGVDDP 557

  Fly   552 LADQQQE-----HQREKEGIYENIRSLSRELALCELVLNSYVPKEYQSMINQYTHWNEDIGEWQL 611
            |..::.|     |.:::..|:..:..|.||:||.|                          |...
Mosquito   558 LRTEEFERKSEFHTQQQIRIHSELTQLKREIALKE--------------------------ELHR 596

  Fly   612 KCVAYTGNNMRKHISAHKTSGKEPDFLDLSHVY----------------LSYNTDGVSNPMRSKS 660
            ||   .||:..  :.:: ||.:|.:..:..|.|                |..||.  ::..|||.
Mosquito   597 KC---QGNSAA--VQSY-TSRRERELTEQLHEYEGQMRSLEGQLAELNALLENTK--ASEKRSKL 653

  Fly   661 ARPR 664
            |..|
Mosquito   654 AEER 657

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp64D	NP_523934.1	KISc_KIF3	19..352	CDD:276822	142/356 (40%)
		Smc	<433..>578	CDD:440809	32/157 (20%)
LOC4576148	XP_061512564.1	None