Protein Alignment Klp64D and Kif3C

DIOPT Version :10

• Sequence 1: NP_523934.1
• Gene: Klp64D / 38611
• FlyBaseID: FBgn0004380
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_651939.4
• Gene: Kif3C / 43820
• FlyBaseID: FBgn0039925
• Length: 649
• Species: Drosophila melanogaster
• Alignment Length: 677
• Identity: 243/677 - (35%)
• Similarity: 363/677 - (53%)
• Gaps: 83/677 - (12%)

  Fly    19 ENVRVVVRTRPMDKNELSAGALSAISVDKINRAITVMKPNATANEPPKTYYFDNVFDGGSNQMDL 83
            ||::||||.|||::.|......:.:.:::.  |::|..|:|..:: .|.:.||:|::..::...:
  Fly     3 ENIKVVVRCRPMNQTEKERNCQNIVEINEF--AVSVTNPSARISQ-QKKFIFDSVYNMKTDTEVI 64

  Fly    84 YVDTARPIVDKVLEGYNGTILAYGQTGTGKTYTMSGNPDSPQTKGIIPNAFAHIFGHIAKAKENQ 148
            |.:....:|:..:|||||||.||||||.|||:||.|:.:...:.||||..|.|||..|:.. .|.
  Fly    65 YDEMCYSLVESTIEGYNGTIFAYGQTGCGKTHTMQGDENFSNSTGIIPKCFDHIFERISMT-TNV 128

  Fly   149 KFLVRVSYMEIYNEEVRDLLGKDVGKSL---EVKERPDIGVFVKDLSGYVVHNADDLENIMRLGN 210
            ::|..|:|:|||||.:||||.|:...::   .:||.|.|||.|..|:...|.||:...:.:..||
  Fly   129 RYLALVTYLEIYNERIRDLLNKNENTNVINHFLKELPGIGVSVPTLTTQPVVNANQCYDWLHFGN 193

  Fly   211 KNRAVGATKMNQESSRSHAIFSITVERS----ELGEGDVQHVRMGKLQLVDLAGSERQSKTQASG 271
            |||...||.||:.|||||.||:||:|:|    .:|......:..|||.||||||||||.||.|.|
  Fly   194 KNRVTAATLMNKNSSRSHTIFTITLEQSPFLNSIGSDAFGGICRGKLSLVDLAGSERQRKTGAQG 258

  Fly   272 QRLKEATKINLSLSVLGNVISALVDGKSTHIPYRNSKLTRLLQDSLGGNSKTVMCATISPADSNY 336
            .|||||::||||||.||||||:|||||:.|:|:|:||||||||||||||:||:|.:.|||.|.:|
  Fly   259 DRLKEASQINLSLSALGNVISSLVDGKAKHVPFRDSKLTRLLQDSLGGNTKTLMISCISPTDIHY 323

  Fly   337 METISTLRYASRAKNIQNRMHINEEPKDALLRHFQEEIARLRKQLEEGDSLEEEPPSSEEEEDTA 401
            .|||||||||||||||.|:..|||:||||.||.:|.||..|::.|:|...:       ..:.:..
  Fly   324 DETISTLRYASRAKNISNKPKINEDPKDARLRQYQNEILYLKRMLQESQQI-------INKNNDP 381

  Fly   402 DDELEAPLEIELESSTIQAVEKKPKKKREKTDAEKEELAKRKNEH------QKEIEHAKTEQETL 460
            :..:::||:|      ||.......|..:..|..:...|..|..:      ...:..:|.|.:..
  Fly   382 NKIIKSPLKI------IQHTNMNSTKNVQIIDLGRNCKASFKTNNSILTKPNFPLIQSKEEVQLQ 440

  Fly   461 RNKLVSLEGKILVGGE-----NLLEKAQTQELLLEQSIA----ELEQHEKSEEALKQTLQQKATE 516
            ....:.|..:.|:|||     .|.||...::...::.::    .|.:.:..:..|.|......|:
  Fly   441 ARSRIDLIKRSLIGGERIHDFELKEKHMARKYAAQRHLSAIAIALSRVKCEDRDLLQGHYATITQ 505

  Fly   517 RIDIEERYSTLQDASTGITKKIHRVMQMLMGVKSELADQQQEHQREKEGIYENIRSLSRELALCE 581
            .|||:..|             |.:..:.:..::.|::|...|.|.::|...:.||:|.|::...:
  Fly   506 EIDIKNDY-------------IRKCKEKIKMLEMEVSDLNSEFQLDREDYLDEIRNLGRQVKFHQ 557

  Fly   582 LVLNSYV--PKEYQ-----SMINQYTHWNEDIGEWQ-----------------LKCV-------A 615
            .:...:.  |.::.     ..|.|.:.||:|:..|:                 |.|:       .
  Fly   558 QLFLKFSSNPGKFDRNWTPDTILQNSLWNDDLKMWRIPESDLIKLPPATQKSGLHCIHPLVIHSE 622

  Fly   616 YTGNNMRKHISAHKTSGKEPDFLDLSH 642
            ...||..:.:...|.|.....||.||:
  Fly   623 NQHNNQNEIVVGEKVSISNIAFLFLSY 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp64D	NP_523934.1	KISc_KIF3	19..352	CDD:276822	171/339 (50%)
		Smc	<433..>578	CDD:440809	31/159 (19%)
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:473979	171/339 (50%)