Protein Alignment Klp64D and Klp98A

DIOPT Version :10

• Sequence 1: NP_523934.1
• Gene: Klp64D / 38611
• FlyBaseID: FBgn0004380
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_524532.2
• Gene: Klp98A / 43310
• FlyBaseID: FBgn0004387
• Length: 1265
• Species: Drosophila melanogaster
• Alignment Length: 774
• Identity: 219/774 - (28%)
• Similarity: 344/774 - (44%)
• Gaps: 204/774 - (26%)

  Fly    18 IENVRVVVRTRPMDKNELSAGALSAISVDKINRAITVMKPN-ATANEPPKTYYFDNVFDGG---- 77
            :.:::|.||.||.:..|:...|...:.::  |:...::||. .:..:..:..:.|..||..
  Fly     1 MSSLKVAVRVRPFNSREIDMDAQLIMEME--NKKTRLLKPRLQSIRDAGRDNHHDFTFDYSYWSF 63

  Fly    78 -------SNQMDLYVDTARPIVDKVLEGYNGTILAYGQTGTGKTYTMSGNPDSPQTKGIIPNAFA 135
                   :.|..:|.|....:||...||||..:.||||||:|||:||.|.|::|   |:||....
  Fly    64 DAEDPHFATQEQVYSDLGNDVVDCAYEGYNACVFAYGQTGSGKTFTMMGTPNNP---GLIPRICE 125

  Fly   136 HIFGHIAKAKEN-QKFLVRVSYMEIYNEEVRDLL-GKDVGKSLEVKERPDIGVFVKDLSGYVVHN 198
            .:|..:...:|: ..:....||:|||||.|:||| .:..|..|.|:|...:|.:|::||.:.|.:
  Fly   126 ELFARMRVGQESGTGYRTHASYLEIYNERVKDLLAAQSTGHGLRVREHRSLGPYVENLSQHAVSD 190

  Fly   199 ADDLENIMRLGNKNRAVGATKMNQESSRSHAIFSITVERSELGEGDVQHVRMGKLQLVDLAGSER 263
            .|:::..:..||..|...:|.||..||||||||:||..:: :...|:....:.|:.|||||||||
  Fly   191 FDEIQECIARGNAQRTTASTNMNDTSSRSHAIFTITFVQA-VFMNDMPSETVSKIHLVDLAGSER 254

  Fly   264 QSKTQASGQRLKEATKINLSLSVLGNVISALVD------------------GKS---THIPYRNS 307
            .:.|.|:||||||...||.||..||:|||||.:                  |.|   .:||||:|
  Fly   255 ANATGATGQRLKEGAHINKSLVTLGSVISALAEQTGGGHNSSSSALATTPNGASKRVLYIPYRDS 319

  Fly   308 KLTRLLQDSLGGNSKTVMCATISPADSNYMETISTLRYASRAKNIQNRMHINEEPKDALLRHFQE 372
            .||.||:|||||||||:|.|.:||||.||.||:||||||:|||||.|:..:||:....|:|..:|
  Fly   320 ILTWLLKDSLGGNSKTIMIAALSPADCNYSETLSTLRYANRAKNIINKPTVNEDTNVKLIRELRE 384

  Fly   373 EIARLRKQLEEGDSLEEEP--------PSSEEEEDTADDE-----------LEAPLEIELESSTI 418
            ||.:|:..| .||....:|        ...|.:|....:|           |:....:.|..|.:
  Fly   385 EINKLKSML-AGDIHSLQPSLKVLADLQKKEAQEKVLTEEWTEKWKVAQSILQEQKSLGLRKSGV 448

  Fly   419 QAV-------------------------EKKPKKKREKTD-AEKEELA----------------- 440
            ..|                         |.:.:...|..| |:..|||
  Fly   449 GVVLDSEMPHLIGIHNDVTTGVTLYSLKEGETRIGSEDADVAQDIELAGDGIRAQHCSIFLKGGV 513

  Fly   441 -------------------KRKNEHQKEI---------------EHAKTEQETLRNKL-VSLEGK 470
                               :.|...|.:|               |.||..::..|::| :|....
  Fly   514 VTLHPWPLAQCWVNAHLIDEPKQISQGDIILLGRTNIFRFNNPAEAAKLRKDLSRSQLDMSRLSL 578

  Fly   471 ILVGGENLL-----------------EKAQTQELLLEQSIAEL-EQHEKSEEALKQTLQQKATER 517
            |....||||                 |:....:..:.:...|| :::.|..:.::..|:|...||
  Fly   579 ITSSKENLLTCSIYSDEDGASPYKRPERQYYPQRPMSRDDPELQDENRKILDTIENALKQLNVER 643

  Fly   518 IDIEERYSTLQDASTGITKKIHRVMQMLMGVKSELAD-------QQQE---------HQREKEGI 566
            :.:.::|.|          |:.::.:.|:.::.|..|       ::||         .::..|.:
  Fly   644 VQMHDQYKT----------KVRKLTEELIRLEQEEMDGLQLLNCREQELIARKDMLLWEKNNEKV 698

  Fly   567 YENIRSLSRELALCELVLNS-------YVPKEYQSM------------INQYTHWNEDI 606
            ..:|  :.|:::..:..|:|       ||.||.|.:            |.:.|..|:::
  Fly   699 QIDI--VCRQISAFQTQLDSKKRDFSEYVAKELQELQDCGKLDEMGMKIEEGTPLNDEL 755

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp64D	NP_523934.1	KISc_KIF3	19..352	CDD:276822	147/367 (40%)
		Smc	<433..>578	CDD:440809	38/231 (16%)
Klp98A	NP_524532.2	KISc_KIF1A_KIF1B	2..371	CDD:276816	150/374 (40%)
		Kinesin_assoc	370..478	CDD:465047	19/108 (18%)
		FHA_KIF16	449..556	CDD:438760	11/106 (10%)
		SMC_N	624..>864	CDD:481474	26/144 (18%)
		PX_KIF16B_SNX23	1131..1259	CDD:132784