Protein Alignment Klp64D and Klp68D

DIOPT Version :10

• Sequence 1: NP_523934.1
• Gene: Klp64D / 38611
• FlyBaseID: FBgn0004380
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_524029.2
• Gene: Klp68D / 39332
• FlyBaseID: FBgn0004381
• Length: 784
• Species: Drosophila melanogaster
• Alignment Length: 693
• Identity: 266/693 - (38%)
• Similarity: 395/693 - (56%)
• Gaps: 76/693 - (10%)

  Fly     1 MPQEEANAGT-TAQLDDEIENVRVVVRTRPMDKNELSAGALSAISVDKINRAITVMKPNATAN-E 63
            |..:....|| ::|..:|.  |:||||.|||...|.|..:...::|.. ||.:..::.....| |
  Fly     1 MSAKSRRPGTGSSQTPNEC--VQVVVRCRPMSNRERSERSPEVVNVYP-NRGVVELQNVVDGNKE 62

  Fly    64 PPKTYYFDNVFDGGSNQMDLYVDTARPIVDKVLEGYNGTILAYGQTGTGKTYTMSGNPDSPQTKG 128
            ..|.:.:|..:|..:.|..||.:...|:|..||||:||.|.||||||||||:||.|...:.:..|
  Fly    63 QRKVFTYDAAYDASATQTTLYHEVVFPLVSSVLEGFNGCIFAYGQTGTGKTFTMEGVRGNDELMG 127

  Fly   129 IIPNAFAHIFGHIAKAKENQKFLVRVSYMEIYNEEVRDLLGKDVGKSLEVKERPDIGVFVKDLSG 193
            |||..|..|:.||.:. ||.:|||.|||:|||.||:|||| |...|.|||:||.. ||:|.:|..
  Fly   128 IIPRTFEQIWLHINRT-ENFQFLVDVSYLEIYMEELRDLL-KPNSKHLEVRERGS-GVYVPNLHA 189

  Fly   194 YVVHNADDLENIMRLGNKNRAVGATKMNQESSRSHAIFSITVERSELGEGDVQHVRMGKLQLVDL 258
            ....:.:|:..:|::|||||.||.|.||:.||||||||.|.:   |:.:.:...:::|||.|:||
  Fly   190 INCKSVEDMIKVMQVGNKNRTVGFTNMNEHSSRSHAIFMIKI---EMCDTETNTIKVGKLNLIDL 251

  Fly   259 AGSERQSKTQASGQRLKEATKINLSLSVLGNVISALVDGKSTHIPYRNSKLTRLLQDSLGGNSKT 323
            |||||||||.||.:|||||:||||:||.||||||||.: .|.|:|||:|||||||||||||||||
  Fly   252 AGSERQSKTGASAERLKEASKINLALSSLGNVISALAE-SSPHVPYRDSKLTRLLQDSLGGNSKT 315

  Fly   324 VMCATISPADSNYMETISTLRYASRAKNIQNRMHINEEPKDALLRHFQEEIARLRK-------QL 381
            :|.|.|.|::.||.||::|||||||||:|||:...||:|:||.|:.:||||.||::       |.
  Fly   316 IMIANIGPSNYNYNETLTTLRYASRAKSIQNQPIKNEDPQDAKLKEYQEEIERLKRLIGPQQQQR 380

  Fly   382 EEGDSLEEEPPSSEEEEDTADDELEAPLEIELESSTI-QAVE--KKPKKKREKTDAEKEELAKRK 443
            .|.....::....:.:::|...|:...|::    ||| |.||  ..|:....::|.|.|....:.
  Fly   381 SEKQVTAKKQRVKKPKKETVTKEMSDSLQV----STIEQPVEDDSDPEGAESESDKENEAEVAKS 441

  Fly   444 NEHQKEIEHAKTEQETLRNKLVSLEGKILVGGENLLEKAQTQELLLEQSIAELEQHEKSEEALKQ 508
            ||   |:|..:.|...|..||..|||:::.||:|||:....:::.||:.:.|:.:.:|.|..::|
  Fly   442 NE---ELERERVENSKLAAKLAELEGQLVRGGKNLLDTYSERQIELEKKLVEIAERKKREIEIQQ 503

  Fly   509 TLQQKATERIDIEERYSTLQDASTGITKKIHRVMQMLMGVKSELADQQQEHQREKEGI----YEN 569
            .|:.:....::|.||..:|:.......:|:.:.....:.::.||.|.:.:|.::...:    .|.
  Fly   504 QLELQEETTLEIRERNVSLEQEVELKKRKLSKCYAKYLALQQELNDCKSDHNQDLRELEMAQNEL 568

  Fly   570 IRSLSRELALCELVLNSYVPKEYQSMINQYTHWNEDIGEWQLKCVAYT----GNNMRKHISAHKT 630
            ::.|.|:|    |:::::||.|.:..:.....::|:..||:...::..    |:.        |.
  Fly   569 VKELKRQL----LIIDNFVPIEVKQRLYTQAKYDEEQEEWKFSSMSLPTPPGGDG--------KF 621

  Fly   631 SGKEPDFLDLSHVYLSYNTDGVSNPMRSKSARPRTSGVPRPTT 673
            |.|.|                ||:|.|.           |||:
  Fly   622 SSKRP----------------VSHPQRR-----------RPTS 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp64D	NP_523934.1	KISc_KIF3	19..352	CDD:276822	176/333 (53%)
		Smc	<433..>578	CDD:440809	38/148 (26%)
Klp68D	NP_524029.2	KISc	20..351	CDD:214526	179/338 (53%)
		Smc	<431..>580	CDD:440809	40/155 (26%)